axcelto 20mg tablet - Uses, Price, Side Effects & Substitutes
What is axcelto 20mg tablet used for?
Anna 2.5mg Tablet (Rivaroxaban) is used to treat CARDIAC. It contains Rivaroxaban (20mg), which Direct factor Xa inhibitor; inhibits both free and clot-bound factor Xa, reducin. Always consult your doctor before use. Take as prescribed.
- Generic Name: Rivaroxaban
- Manufacturer: Akcent Healthcare
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ axcelto 20mg tablet Uses & Benefits
Prevention of venous thromboembolism (VTE) in hip/knee replacement, stroke prevention in non-valvular atrial fibrillation, treatment of DVT/PE, prevention of recurrent DVT/PE.
Off-label uses: Anticoagulation in antiphospholipid syndrome (limited data), prevention of thromboembolism in cancer patients.
๐ Drug Information
| Generic Name(s) | Rivaroxaban |
| Brand Name | Anna 2.5mg Tablet |
| Manufacturer | Akcent Healthcare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Oral Factor Xa Inhibitors |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Direct factor Xa inhibitor; inhibits both free and clot-bound factor Xa, reducing thrombin generation.
Mechanism Steps
๐ก How to Take axcelto 20mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of axcelto 20mg tablet
โ Common Side Effects
- Bleeding (epistaxis, bruising, gingival bleeding)
- Anemia
- Nausea
- Diarrhea
- Dizziness
๐จ Serious Side Effects
- Major bleeding (intracranial, gastrointestinal, retroperitoneal)
- Spinal hematoma with neuraxial anesthesia
- Acute renal failure
- Hepatic injury
โ ๏ธ Rare Side Effects
- Stevens-Johnson syndrome
- Anaphylactic reactions
- Thrombocytopenia
- Jaundice
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Heparin | Major | Increased bleeding risk |
| Enoxaparin | Major | Increased bleeding risk |
| Clopidogrel | Major | Increased bleeding risk |
| Aspirin | Major | Increased bleeding risk |
| NSAIDs | Major | Increased bleeding risk |
| Rifampin | Major | Decreased rivaroxaban efficacy |
| Phenytoin | Major | Decreased rivaroxaban efficacy |
| Carbamazepine | Major | Decreased rivaroxaban efficacy |
| St. John's Wort | Major | Decreased rivaroxaban efficacy |
| Amiodarone | Moderate | Increased rivaroxaban exposure |
| Dronedarone | Moderate | Increased rivaroxaban exposure |
| Verapamil | Moderate | Increased rivaroxaban exposure |
| Diltiazem | Moderate | Increased rivaroxaban exposure |
| Clarithromycin | Moderate | Increased rivaroxaban exposure |
| Erythromycin | Moderate | Increased rivaroxaban exposure |
| Fluconazole | Moderate | Increased rivaroxaban exposure |
| Ketoconazole | Moderate | Increased rivaroxaban exposure |
| Itraconazole | Moderate | Increased rivaroxaban exposure |
| Ritonavir | Moderate | Increased rivaroxaban exposure |
| Atorvastatin | Minor | No significant interaction |
| Digoxin | Minor | No significant interaction |
| Omeprazole | Minor | No significant interaction |
| Ranitidine | Minor | No significant interaction |
| Antacids | Minor | No significant interaction |
๐จ Major Interactions
- Warfarin
- Heparin
- Enoxaparin
- Clopidogrel
- Aspirin
- NSAIDs
- Rifampin
- Phenytoin
- Carbamazepine
- St. John's Wort
โก Moderate Interactions
- Amiodarone
- Dronedarone
- Verapamil
- Diltiazem
- Clarithromycin
- Erythromycin
- Fluconazole
- Ketoconazole
- Itraconazole
- Ritonavir
โน๏ธ Minor Interactions
- Atorvastatin
- Digoxin
- Omeprazole
- Ranitidine
- Antacids
๐ฝ๏ธ Food Interactions
Food does not affect absorption; can be taken with or without food.
๐ท Alcohol Interaction
Alcohol may increase bleeding risk; avoid excessive consumption.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Active bleeding, severe renal impairment (CrCl <15 mL/min), hepatic disease with coagulopathy, hypersensitivity to rivaroxaban.
๐ Monitoring Parameters
Renal function, hepatic function, signs of bleeding, PT/aPTT (not routinely needed).
๐คฑ Lactation Safety
Not recommended; excreted in breast milk in animal studies.
๐ Overdose Management
Activated charcoal if recent ingestion; consider prothrombin complex concentrate (PCC) or recombinant factor VIIa for bleeding.
โฐ Missed Dose
Take as soon as remembered; skip if near next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for axcelto 20mg tablet
View AllAlternative brands with exact same active ingredient (Rivaroxaban (20mg)):
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cameriv 20mg tabletAlembic Pharmaceuticals Ltd โน105.94 89.2% CHEAPER
-
rivatane 20 tabletMedley Pharmaceuticals โน140.00 85.7% CHEAPER
-
rpigat 20mg tabletNatco Pharma Ltd โน140.00 85.7% CHEAPER
-
xarex 20mg tabletAlteus Biogenics Pvt Ltd โน150.00 84.7% CHEAPER
-
rivoxamac 20mg tabletMacleods Pharmaceuticals Pvt Ltd โน160.00 83.7% CHEAPER
-
rivaxon 20mg tabletGlenmark Pharmaceuticals Ltd โน168.00 82.9% CHEAPER
-
viklot 20 tabletHetero Healthcare Limited โน176.00 82% CHEAPER
-
alriza 20 tabletAlniche Life Sciences Pvt Ltd โน178.13 81.8% CHEAPER
-
ricosprin 20 tabletUSV Ltd โน180.00 81.6% CHEAPER
-
rivastar 20mg tabletOrris Pharmaceuticals โน180.00 81.6% CHEAPER
Medical Note: Always consult your doctor before switching medications.