alriza 20 tablet - Rivaroxaban (20mg) medicine

Alriza 20 Tablet - Uses, Price, Side Effects

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๐Ÿญ Alniche Life Sciences Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is alriza 20 tablet used for?

Alriza 20 Tablet contains Rivaroxaban 20mg, an anticoagulant that works by inhibiting Factor Xa, thereby preventing blood clot formation. It is used to treat and prevent deep vein thrombosis (DVT), pulmonary embolism (PE), and to reduce stroke risk in atrial fibrillation. It is typically taken once daily with food.

  • Generic Name: Rivaroxaban
  • Manufacturer: Alniche Life Sciences Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š alriza 20 tablet Uses & Benefits

Prevention of venous thromboembolism (VTE) in hip/knee replacement, stroke prevention in non-valvular atrial fibrillation, treatment of DVT/PE, prevention of recurrent DVT/PE.

Off-label uses: Anticoagulation in antiphospholipid syndrome (limited data), prevention of thromboembolism in cancer patients.

๐Ÿ“‹ Drug Information

Generic Name(s)Rivaroxaban
Brand NameAnna 2.5mg Tablet
ManufacturerAlniche Life Sciences Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassOral Factor Xa Inhibitors
Route of AdministrationOral
StorageStore at 20-25ยฐC (68-77ยฐF); protect from moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRivaroxaban is rapidly absorbed after oral administration with high oral bioavailability.
DistributionWidely distributed in tissues; volume of distribution approximately 50 L.
Protein BindingApproximately 92-95% bound to plasma proteins, primarily albumin.
MetabolismMetabolized via CYP3A4, CYP2J2, and CYP-independent mechanisms; also hydrolyzed by amidases.
Half-Life5-9 hours in young adults; 11-13 hours in elderly.
ExcretionTwo-thirds metabolized and excreted equally via renal and fecal routes; one-third excreted unchanged in urine.
Bioavailability80-100% for 2.5 mg dose; dose-dependent.
Onset of ActionRapid; within 2-4 hours.
Peak Plasma Time2-4 hours after oral administration.
Duration of ActionApproximately 24 hours due to once-daily dosing.

How It Works

Direct factor Xa inhibitor; inhibits both free and clot-bound factor Xa, reducing thrombin generation.

Mechanism Steps

1Rivaroxaban binds directly to the active site of factor Xa (both free and clot-bound).
2Inhibition of factor Xa prevents conversion of prothrombin to thrombin.
3Reduced thrombin generation decreases fibrin formation and platelet activation.

๐Ÿ’ก How to Take alriza 20 tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of alriza 20 tablet

โœ… Common Side Effects

  • Bleeding (epistaxis, bruising, gingival bleeding)
  • Anemia
  • Nausea
  • Diarrhea
  • Dizziness

๐Ÿšจ Serious Side Effects

  • Major bleeding (intracranial, gastrointestinal, retroperitoneal)
  • Spinal hematoma with neuraxial anesthesia
  • Acute renal failure
  • Hepatic injury

โš ๏ธ Rare Side Effects

  • Stevens-Johnson syndrome
  • Anaphylactic reactions
  • Thrombocytopenia
  • Jaundice

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Aspirin Major Increased bleeding risk
Clopidogrel Major Increased bleeding risk
NSAIDs Moderate Increased bleeding risk
Antifungals (Ketoconazole) Moderate Increased rivaroxaban levels

๐Ÿšจ Major Interactions

  • Warfarin
  • Heparin
  • Enoxaparin
  • Clopidogrel
  • Aspirin
  • NSAIDs
  • Rifampin
  • Phenytoin
  • Carbamazepine
  • St. John's Wort

โšก Moderate Interactions

  • Amiodarone
  • Dronedarone
  • Verapamil
  • Diltiazem
  • Clarithromycin
  • Erythromycin
  • Fluconazole
  • Ketoconazole
  • Itraconazole
  • Ritonavir

โ„น๏ธ Minor Interactions

  • Atorvastatin
  • Digoxin
  • Omeprazole
  • Ranitidine
  • Antacids

๐Ÿฝ๏ธ Food Interactions

Food does not affect absorption; can be taken with or without food.

๐Ÿท Alcohol Interaction

Alcohol may increase bleeding risk; avoid excessive consumption.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Moderate
Kidney
Moderate
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Active bleeding, severe renal impairment (CrCl <15 mL/min), hepatic disease with coagulopathy, hypersensitivity to rivaroxaban.

๐Ÿ“Š Monitoring Parameters

Renal function, hepatic function, signs of bleeding, PT/aPTT (not routinely needed).

๐Ÿคฑ Lactation Safety

Not recommended; excreted in breast milk in animal studies.

๐Ÿ’Š Overdose Management

Activated charcoal if recent ingestion; consider prothrombin complex concentrate (PCC) or recombinant factor VIIa for bleeding.

โฐ Missed Dose

Take as soon as remembered; skip if near next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

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๐Ÿ”„ Substitutes for alriza 20 tablet

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Alternative brands with exact same active ingredient (Rivaroxaban (20mg)):

Medical Note: Always consult your doctor before switching medications.

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