Avtra 200mg Capsule - Uses, Price, Side Effects
What is avtra 200mg capsule used for?
Avtra 200mg Capsule contains Itraconazole, an antifungal medication used to treat infections caused by fungi, such as athlete's foot, ringworm, and yeast infections. It works by stopping the growth of fungi. It is usually taken with food and the dosage depends on the type of infection.
- Generic Name: Itraconazole
- Manufacturer: Avunu Life Sciences
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ avtra 200mg capsule Uses & Benefits
Onychomycosis, dermatophytosis, candidiasis, histoplasmosis, blastomycosis, aspergillosis.
Off-label uses: Coccidioidomycosis, sporotrichosis, chromoblastomycosis, prophylaxis in immunocompromised patients.
๐ Drug Information
| Generic Name(s) | Itraconazole |
| Brand Name | Alcros 100 Capsule |
| Manufacturer | Avunu Life Sciences |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | OPHTHAL |
| Action Class | Fungal ergosterol synthesis inhibitor |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits fungal cytochrome P450 14ฮฑ-demethylase, blocking ergosterol synthesis and disrupting fungal cell membrane.
Mechanism Steps
๐ก How to Take avtra 200mg capsule
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of avtra 200mg capsule
โ Common Side Effects
- Nausea
- Abdominal pain
- Diarrhea
- Headache
- Dizziness
- Rash
๐จ Serious Side Effects
- Hepatotoxicity
- Congestive heart failure
- QT prolongation
- Torsades de pointes
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Peripheral neuropathy
- Adrenal suppression
- Hypokalemia
- Gynecomastia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Cisapride | Major | Risk of cardiac arrhythmias |
| Statins | Moderate | Increased risk of myopathy |
๐จ Major Interactions
- CYP3A4 substrates (e.g., midazolam, triazolam)
- HMG-CoA reductase inhibitors (e.g., simvastatin, lovastatin)
- Ergot alkaloids
- Cisapride
- Pimozide
- Quinidine
- Dofetilide
- Lovastatin
- Simvastatin
โก Moderate Interactions
- Warfarin
- Oral hypoglycemics
- Calcium channel blockers
- Digoxin
- Cyclosporine
- Tacrolimus
- Sirolimus
- Carbamazepine
- Phenytoin
- Rifampin
- Isoniazid
- Antacids
- H2 blockers
- Proton pump inhibitors
โน๏ธ Minor Interactions
- Corticosteroids
- Benzodiazepines (e.g., alprazolam)
- Oral contraceptives
๐ฝ๏ธ Food Interactions
Absorption increased with acidic beverages (e.g., cola) and food; avoid grapefruit juice.
๐ท Alcohol Interaction
Avoid alcohol due to potential hepatotoxicity.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to itraconazole or excipients; concomitant use with CYP3A4 substrates with narrow therapeutic index; ventricular dysfunction; pregnancy (category C).
๐ Monitoring Parameters
Liver function tests (ALT, AST), serum potassium, ECG (QT interval), therapeutic drug monitoring if needed.
๐คฑ Lactation Safety
Excreted in breast milk; use with caution.
๐ Overdose Management
Supportive care; no specific antidote; gastric lavage if recent; monitor liver function and ECG.
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for avtra 200mg capsule
View AllAlternative brands with exact same active ingredient (Itraconazole (200mg)):
-
itrazeal 200mg capsuleGlantis Pharmaceutical โน20.63 87.5% CHEAPER
-
itrapro 200mg capsuleKitnix Pvt Ltd โน33.98 79.4% CHEAPER
-
davaindia itraconazole 200mg capsuleDavaindia Generic Pharmacy โน39.38 76.1% CHEAPER
-
fungizee 200 capsuleZeelab Pharmacy Pvt Ltd โน40.00 75.8% CHEAPER
-
candimore 200mg capsuleMorepen Laboratories Ltd โน45.00 72.7% CHEAPER
-
itrobid 200mg capsuleEuro Organics โน45.94 72.2% CHEAPER
-
itraks 200mg capsuleAxis Life Science Pvt Ltd โน48.75 70.5% CHEAPER
-
itrapic 200mg capsuleAtopic Laboratories โน60.94 63.1% CHEAPER
-
itrason 200 capsuleUnison Pharmaceuticals Pvt Ltd โน64.09 61.2% CHEAPER
-
itrapuri 200mg capsuleRavian Life Science Pvt Ltd โน65.63 60.2% CHEAPER
Medical Note: Always consult your doctor before switching medications.