at cad cream - Terbinafine (1% w/w) + Clobetasol (0.05% w/w) medicine

Laboderm-OC Cream: Complete Medicine Guide

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🏭 Avunu Life Sciences 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for short-term use in inflammatory fungal skin infections.
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction with swelling of face, lips, or throat
  • Signs of systemic corticosteroid effects such as facial swelling, weight gain, or high blood sugar
  • Severe skin thinning, stretch marks, or easy bruising
  • Increasing pain, warmth, or pus at the application site
  • Blistering or peeling of the skin
  • Vision problems or eye pain if cream accidentally gets into the eyes
  • Symptoms of adrenal suppression like extreme fatigue, weakness, nausea, or low blood pressure

If experiencing severe symptoms, call emergency services immediately.

What is at cad cream used for?

This medicine is a topical cream combining terbinafine (an antifungal) and clobetasol (a strong steroid). It is used for short-term treatment of inflamed fungal skin infections like ringworm. Apply a thin layer to the affected area as prescribed, usually for 1-2 weeks. Do not use on the face or for prolonged periods without medical advice.

  • Generic Name: Terbinafine (1% w/w) + Clobetasol (0.05% w/w)
  • Manufacturer: Avunu Life Sciences
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 at cad cream के बारे में (Hindi Summary)

उपयोग: यह दवा एक टॉपिकल क्रीम है जिसमें टर्बिनाफाइन और क्लोबेटासोल होते हैं। इसका उपयोग फंगल त्वचा संक्रमण जैसे दाद, खुजली और एथलीट फुट के इलाज के लिए किया जाता है, खासकर जब सूजन और लालिमा हो। यह क्रीम फंगस को मारती है और सूजन को कम करती है। इसे डॉक्टर के निर्देशानुसार ही लगाएं और 1-2 सप्ताह से ज्यादा इस्तेमाल न करें।

साइड इफेक्ट्स: आम दुष्प्रभावों में लगाने की जगह पर जलन, खुजली, या लालिमा शामिल हैं। लंबे समय तक उपयोग से त्वचा पतली हो सकती है, खिंचाव के निशान पड़ सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको तेज एलर्जी, सूजन, या त्वचा पर चकत्ते दिखें तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस क्रीम को केवल बाहरी त्वचा पर लगाएं। आंखों, मुंह और नाक के अंदर न लगाएं। डॉक्टर के बताए समय से ज्यादा इस्तेमाल न करें। अगर आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 at cad cream Uses & Benefits

[{"condition":"Tinea corporis with inflammation","description":"Used for short-term treatment of ringworm of the body when significant redness, itching, and swelling are present.","evidence":"Well-established for the combination in short-term use"},{"condition":"Tinea cruris with inflammation","description":"Used for jock itch with marked inflammatory symptoms, but only for a limited duration and with caution due to the sensitive skin area.","evidence":"Well-established for short-term use"},{"condition":"Tinea pedis with inflammation","description":"Used for athlete's foot with pronounced inflammation, itching, and burning, typically for one to two weeks.","evidence":"Well-established for short-term use"}]

Off-label uses: [{"condition":"Inflammatory dermatophytosis unresponsive to plain antifungals","description":"Sometimes prescribed off-label for severe inflammatory fungal infections where a plain antifungal alone is not controlling the inflammation.","evidence":"Limited"}]

Primary treatment for: Inflammatory dermatophytosis (tinea infections with inflammation)

Also treats: Tinea corporis, Tinea cruris, Tinea pedis

📋 Drug Information

Generic Name(s)Terbinafine (1% w/w) + Clobetasol (0.05% w/w)
Brand Nameat cad cream
ManufacturerAvunu Life Sciences
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action Class
Route of AdministrationTopical
StorageStore at room temperature between 15°C and 30°C. Protect from direct sunlight and moisture. Keep the tube tightly closed when not in use.
Shelf Life24 months from the date of manufacture, or as printed on the pack.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Apply a thin film of the cream only to the affected area and a small margin around it.
2
Do not use this cream for more than 2 weeks unless your doctor specifically instructs you to do so.
3
Avoid using this cream on the face, groin, or underarms unless your doctor has specifically prescribed it for those areas.
4
If you are using other topical products, apply this medicine first and wait a few minutes before applying others.
5
Wash your hands thoroughly after applying the cream to prevent accidental transfer to other parts of the body.
6
Do not cover the treated area with tight bandages or dressings unless your doctor tells you to.
7
If your symptoms do not improve within the prescribed time or worsen, contact your doctor promptly.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Itchy, red, ring-shaped rash
This medicine is commonly prescribed for this.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary
❌
Bacterial skin infection with pus
This medicine is not for bacterial infections.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionTerbinafine is poorly absorbed through intact skin, with less than 5% of a topical dose reaching systemic circulation. Clobetasol propionate can be absorbed through the skin, especially when applied to large areas, broken skin, or under occlusive dressings. Systemic absorption of clobetasol may lead to adrenal suppression if used excessively.
DistributionOnce absorbed, terbinafine is highly lipophilic and distributes into skin, fat, and other tissues. Clobetasol is also lipophilic and binds extensively to plasma proteins. Both drugs can accumulate in the skin, which contributes to their local effects.
Protein BindingTerbinafine is more than 99% bound to plasma proteins. Clobetasol propionate is also highly protein-bound, primarily to albumin and transcortin.
MetabolismTerbinafine is extensively metabolized in the liver by cytochrome P450 enzymes, mainly CYP2C9, CYP1A2, and CYP3A4. Clobetasol propionate is metabolized in the liver, primarily by CYP3A4, to inactive metabolites.
Half-LifeThe elimination half-life of terbinafine is approximately 36 hours. The half-life of clobetasol propionate is not well established from topical application but is generally short, around 3 to 6 hours for systemic exposure.
ExcretionMetabolites of terbinafine are excreted mainly in the urine, with some in the feces. Clobetasol metabolites are excreted in urine and bile.
BioavailabilityTopical bioavailability of terbinafine is low, less than 5%. The bioavailability of clobetasol from topical application depends on the vehicle, skin condition, and application site, and can range from 1% to 10% or more under occlusion.
Onset of ActionImprovement in itching and inflammation may be noticed within a few days of starting treatment. Antifungal effects on the fungus begin immediately but visible clearance of the infection typically takes one to two weeks.
Peak Plasma TimePeak plasma concentrations after topical application are generally low and variable. For terbinafine, peak levels are not well defined for topical use. For clobetasol, peak systemic levels occur within a few hours after application.
Duration of ActionThe anti-inflammatory effect of clobetasol lasts for several hours after application. The antifungal effect of terbinafine persists in the skin for days after stopping, allowing for once or twice daily dosing.

How It Works

This medicine works through two complementary mechanisms. Terbinafine inhibits the fungal enzyme squalene epoxidase, which blocks the synthesis of ergosterol, a vital component of the fungal cell membrane. This leads to accumulation of squalene and increased membrane permeability, ultimately killing the fungus. Clobetasol propionate binds to glucocorticoid receptors in the skin, reducing the production of inflammatory mediators and suppressing the local immune response. This rapidly decreases redness, itching, and swelling. The combination provides both antifungal action and symptomatic relief of inflammation.

Mechanism Steps

1
Terbinafine inhibits squalene epoxidase: Terbinafine binds to and inhibits the fungal enzyme squalene epoxidase, blocking the conversion of squalene to lanosterol, a precursor of ergosterol.
2
Fungal cell membrane disruption: The lack of ergosterol and accumulation of squalene weaken the fungal cell membrane, leading to leakage of cellular contents and fungal cell death.
3
Clobetasol binds glucocorticoid receptors: Clobetasol propionate enters skin cells and binds to cytoplasmic glucocorticoid receptors, which then translocate to the nucleus.
4
Suppression of inflammatory mediators: The activated receptor complex inhibits the transcription of pro-inflammatory cytokines and enzymes such as phospholipase A2, reducing redness, itching, and swelling.

💡 How to Take at cad cream

Strength: Cream containing terbinafine 1% w/w and clobetasol propionate 0.05% w/w.

1Wash your hands thoroughly before and after applying the cream.
2Clean and dry the affected skin area gently.
3Apply a thin film of the cream to the affected area and a small margin around it.
4Rub it in gently until it disappears. Do not cover with a bandage unless instructed.
5Use the cream exactly as prescribed, usually once or twice daily.
6Do not use more than the recommended amount or for longer than the prescribed duration.

Dosage Information

Adult DosageApply a thin film of this medicine to the affected skin area once or twice daily, or as directed by your doctor. The usual duration of treatment is 1 to 2 weeks. Do not use for longer than prescribed. Dose must be individualized by a qualified clinician based on the indication, severity, and response to treatment.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more susceptible to the effects of topical corticosteroids, including skin thinning. Use the lowest effective amount for the shortest duration. Dose must be individualized by a qualified clinician.
Renal ImpairmentNo dose adjustment is needed for renal impairment with topical use, as systemic absorption is minimal.
Hepatic ImpairmentNo dose adjustment is needed for hepatic impairment with topical use, as systemic absorption is minimal.
Maximum Daily DoseThe maximum daily dose depends on the area treated and the prescribed frequency. Do not exceed the duration and frequency recommended by your doctor. Generally, not more than 50 grams per week of a super-potent topical corticosteroid should be used.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Apply the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not apply a double dose to catch up.

⚠️ Side Effects of at cad cream

✅ Common Side Effects

Application site burning or stinging (Common (1-10%))
This usually settles with continued use. If it persists or worsens, consult your doctor.
Itching at the application site (Common (1-10%))
Avoid scratching. If itching is severe or accompanied by rash, stop and consult your doctor.
Redness or irritation (Common (1-10%))
Apply a thinner layer or less frequently as advised. If redness increases, contact your doctor.

🚨 Serious Side Effects

Skin atrophy (thinning) (Uncommon with short-term use (<1%))
Stop using the cream and consult a dermatologist if you notice skin thinning, easy bruising, or shiny skin.
Stretch marks (striae) (Uncommon (<1%))
Report to your doctor if you see new stretch marks. Do not use on areas prone to stretching.
Adrenal suppression (Rare (<0.1%))
Seek medical attention if you experience fatigue, weakness, nausea, or low blood pressure, especially after prolonged use on large areas.

⚠️ Rare Side Effects

Allergic contact dermatitis
Stop the cream and seek medical help if you develop a severe rash, swelling, or blistering.
Secondary bacterial infection
Consult a doctor if the treated area becomes increasingly painful, warm, or starts oozing pus.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Other topical corticosteroids Major
CYP3A4 inhibitors Moderate
CYP2C9 inhibitors Moderate
CYP1A2 inhibitors Moderate
Other topical products Minor

🚨 Major Interactions

  • Other topical corticosteroids
  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)

⚡ Moderate Interactions

  • CYP2C9 inhibitors (e.g., fluconazole)
  • CYP1A2 inhibitors (e.g., ciprofloxacin)

🍷 Alcohol Interaction

Alcohol is not expected to interact with this topical medicine because systemic absorption is minimal. However, alcohol may worsen certain skin conditions or increase flushing. It is best to avoid excessive alcohol while treating a skin infection.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to terbinafine, clobetasol, or any component of the cream","Bacterial or viral skin infections (e.g., impetigo, herpes simplex)","Acne vulgaris, rosacea, and perioral dermatitis","Use on the face, groin, or underarms unless specifically directed by a doctor","Children under 12 years unless prescribed by a pediatrician"]

⚠️ Warnings & Precautions

["For external use only. Do not swallow.","Avoid contact with eyes, mouth, and mucous membranes.","Do not use for longer than the prescribed duration, usually not more than 2 weeks.","Do not use under occlusive dressings unless directed by a doctor.","Prolonged use can cause skin thinning, stretch marks, and increased hair growth.","If irritation or allergic reaction occurs, stop use and consult a doctor.","Keep out of reach of children.","Do not use on large areas of the body without medical supervision."]

🤱 Lactation Safety

It is not known whether terbinafine or clobetasol pass into breast milk in significant amounts after topical application. To be safe, do not apply this cream to the breast area, and consult your doctor before use while breastfeeding.

💊 Overdose Management

Overdose from topical application is unlikely. If the cream is accidentally swallowed, seek immediate medical attention. Symptoms of corticosteroid overdose may include nausea, vomiting, and weakness. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Apply this medicine exactly as prescribed by your doctor. Wash and dry the affected area gently before applying a thin film of the cream. Do not cover the area with tight bandages or dressings unless your doctor instructs you to do so. Avoid contact with the eyes, mouth, and other mucous membranes. Do not use this medicine for longer than the recommended duration, as prolonged use of the corticosteroid component can cause skin damage. Do not use it on the face, groin, or underarms unless specifically directed by your clinician. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before using this medicine. Keep this medicine out of reach of children. Do not share this medicine with others, even if they have similar symptoms. If your condition does not improve within the prescribed time or worsens, contact your doctor.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to skin thinning and other side effects of topical corticosteroids. Use the lowest effective amount for the shortest duration. Monitor for signs of skin atrophy and systemic steroid effects.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before using this medicine. Topical corticosteroids should be used with caution during pregnancy. Your doctor will weigh the benefits and risks.

🏥 Post-Surgery Considerations

If you have recently had surgery, do not apply this cream to surgical wounds unless specifically directed by your surgeon. It may interfere with wound healing and increase the risk of infection.

🦷 Dental Procedures

This medicine is applied to the skin and is not expected to affect dental procedures. However, inform your dentist about all medicines you are using.

💚 Lifestyle Tips for Better Results

🏃
Keep the affected area clean and dry.
🥗
Avoid sharing towels, clothing, or personal items to prevent spreading the infection.
😴
Wear loose-fitting, breathable clothing to reduce moisture and friction.
💧
Avoid scratching the affected area to prevent worsening of the infection.
🧘
Complete the full course of treatment even if symptoms improve.
🌞
Maintain good personal hygiene and wash hands frequently.

🏋️ Exercise Considerations

You can continue exercising, but keep the affected area clean and dry. Avoid activities that cause excessive sweating or friction on the treated area until the infection clears. If the infection is on your feet, wear clean socks and change them daily.

🥗 Diet Recommendations

Eat a balanced diet rich in fruits and vegetables to support immune function.
Include probiotic foods like yogurt to support gut health.
Stay well hydrated to maintain healthy skin.
Limit sugary and processed foods that may promote inflammation.

💼 Impact on Daily Work & Life

This medicine is applied topically and is unlikely to affect your ability to drive or operate machinery. You can continue your daily activities, but keep the treated area clean and dry. If the infection is on your hands, you may need to avoid certain tasks that require direct contact with others until it clears.

🛑 When to Stop This Medicine

Stop using this medicine after the prescribed duration, usually 1 to 2 weeks, or as directed by your doctor. If your symptoms have not improved or have worsened, consult your doctor before stopping or continuing. Do not stop early without completing the course, as the infection may return.

📅 Long-Term Use Effects

Long-term use of this medicine can cause skin thinning, stretch marks, visible blood vessels, and increased hair growth. It can also lead to systemic absorption of the steroid, potentially causing adrenal suppression, high blood sugar, and other steroid-related effects. It should not be used for more than 2 weeks without medical supervision. Regular monitoring of the skin and, if necessary, adrenal function is advised for prolonged use.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Plain antifungal cream (e.g., terbinafine alone)

For non-inflammatory fungal infections, a plain antifungal cream may be sufficient.

Evidence: Well-established
Oral antifungal medication

For extensive or resistant infections, oral antifungals may be prescribed by a doctor.

Evidence: Well-established
Good hygiene practices

Keeping the skin clean and dry helps prevent fungal infections.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known with this topical medicine. You can receive vaccinations as scheduled. However, if you have a severe skin infection, consult your doctor about the timing of vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case you need to show it at customs. Store it in a cool, dry place away from direct sunlight. If traveling to a hot climate, keep it in a cool bag. No time zone adjustments are needed for topical application. Do not leave it in a hot car.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with itchy, red ring-shaped rash on his arm
He was prescribed this medicine for tinea corporis with inflammation. He applied a thin layer twice daily as directed. Within 3 days, the itching and redness reduced significantly. He completed the 2-week course and the rash cleared completely. He was advised not to use it longer than prescribed.
💡 Lesson: Using the cream exactly as prescribed for the recommended duration leads to good results without side effects.
👤 A 28-year-old woman with jock itch and severe itching
She used this medicine for 10 days as prescribed. The itching and rash improved, but she stopped early because she felt better. The infection returned after a week. Her doctor explained that stopping early can cause recurrence and advised completing the full course next time.
💡 Lesson: Complete the full prescribed course even if symptoms improve, to prevent the infection from coming back.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may notice reduced itching and redness within a few days. The fungal infection usually clears within 1 to 2 weeks of regular use.

Q: Can I use this cream on my face?

A: No, unless your doctor specifically tells you to. The steroid component can cause skin thinning and other problems on the face.

Q: What should I do if I miss a dose?

A: Apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose.

Q: Is it safe to use this cream during pregnancy?

A: Consult your doctor before using this medicine during pregnancy. It is generally not recommended unless clearly needed.

Q: Can I stop using this cream when symptoms improve?

A: No, complete the full course as prescribed to prevent the infection from returning. Stopping early can lead to recurrence.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this cream on my face?
  • How long can I use this cream safely?
  • What if I forget to apply a dose?
  • Can I use this cream if I am pregnant?
  • Does this cream interact with other medicines?
  • Can I stop using this cream when the rash disappears?

🔄 Substitutes for at cad cream

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This cream can be used for any skin rash.
    Fact: This medicine is specifically for inflammatory fungal infections. It should not be used for bacterial or viral rashes.
  • Myth: Using more cream will make it work faster.
    Fact: Applying more than prescribed can increase the risk of side effects like skin thinning. Use only a thin film as directed.
  • Myth: It is safe to use this cream for months.
    Fact: Prolonged use of the steroid component can cause skin damage. It is meant for short-term use only.

🔄 Alternative Options

Generic Alternatives

  • Terbinafine 1% + Clobetasol 0.05% cream

Brand Alternatives

  • Laboderm-OC Cream

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Terbinafine 1% + Clobetasol 0.05%","use":"Inflammatory fungal skin infections","duration":"Short-term (1-2 weeks)"},{"medicine":"Terbinafine cream alone","composition":"Terbinafine 1%","use":"Non-inflammatory fungal infections","duration":"1-2 weeks or longer"},{"medicine":"Clotrimazole + Betamethasone cream","composition":"Clotrimazole 1% + Betamethasone 0.05%","use":"Inflammatory fungal infections","duration":"Short-term (1-2 weeks)"}]

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