avoderm plus cream allopathy (Terbinafine (1% w/w) + Clobetasol (0.05% w/w)) - Uses in Hindi, Side Effects, Substitutes & Price in India
avoderm plus cream allopathy (Terbinafine (1% w/w) + Clobetasol (0.05% w/w)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by Avonic Life Sciences. Contains Terbinafine (1% w/w) + Clobetasol (0.05% w/w).

Avoderm Plus Cream - Uses, Price, Side Effects

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🏭 Avonic Life Sciences 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 20, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is avoderm plus cream used for?

Avoderm Plus Cream is a combination of Terbinafine (1% w/w), an antifungal, and Clobetasol (0.05% w/w), a potent corticosteroid. It is used to treat fungal skin infections like ringworm, athlete's foot, and jock itch, especially when accompanied by inflammation and itching. Terbinafine kills fungi by inhibiting ergosterol synthesis, while clobetasol reduces redness, swelling, and discomfort.

  • Generic Name: Terbinafine + Clobetasol
  • Manufacturer: Avonic Life Sciences
  • Medicine Form: Allopathy
  • Pregnancy Category: C

🇮🇳 avoderm plus cream के बारे में संक्षिप्त जानकारी (Hindi Summary)

avoderm plus cream का उपयोग मुख्य रूप से derma और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Terbinafine (1% w/w) + Clobetasol (0.05% w/w) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

📋 Drug Information

Generic Name(s)Terbinafine + Clobetasol
Brand NameAvoderm Plus Cream
ManufacturerAvonic Life Sciences
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassAntifungal + Corticosteroid
Route of AdministrationTopical
StorageStore at 20-25°C (68-77°F); keep tightly closed.
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionTopical absorption is minimal; systemic absorption is low but enhanced by inflamed skin or prolonged use.
DistributionDistributes into skin layers; systemic distribution limited due to low absorption.
Protein BindingTerbinafine: >99% bound to plasma proteins; Clobetasol: 90-95% bound.
MetabolismTerbinafine: Hepatic via CYP2D6, CYP3A4; Clobetasol: Hepatic via CYP3A4.
Half-LifeTerbinafine: 11-17 hours; Clobetasol: 2-3 hours.
ExcretionTerbinafine: Renal (70%) and fecal; Clobetasol: Renal and biliary.
BioavailabilityLow systemic bioavailability due to topical application.
Onset of ActionWithin 24-48 hours for antifungal effect; corticosteroid effect within hours.
Peak Plasma TimeNot well-defined for topical use.
Duration of ActionAntifungal effect persists for days; corticosteroid effect lasts 12-24 hours.

Pharmacodynamics

Mechanism of ActionTerbinafine inhibits squalene epoxidase, disrupting ergosterol synthesis; Clobetasol binds to glucocorticoid receptors, suppressing inflammation.
Target ReceptorTerbinafine: Squalene epoxidase; Clobetasol: Glucocorticoid receptor.
Pharmacodynamic EffectsAntifungal activity against dermatophytes; anti-inflammatory, antipruritic, and vasoconstrictive effects.

📅 When to take avoderm plus cream?

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

💡 How and when to take avoderm plus cream?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at 20-25°C (68-77°F); keep tightly closed.

⚙️ How avoderm plus cream Works

Terbinafine inhibits squalene epoxidase, disrupting ergosterol synthesis; Clobetasol binds to glucocorticoid receptors, suppressing inflammation.

1 Terbinafine inhibits squalene epoxidase, preventing conversion of squalene to lanosterol.
⬇️
2 Accumulation of squalene and depletion of ergosterol disrupt fungal cell membrane integrity.
⬇️
3 Clobetasol binds to glucocorticoid receptors, modulating gene expression.
⬇️
4 Increased synthesis of lipocortin inhibits phospholipase A2, reducing prostaglandin and leukotriene production.
⬇️
5 Vasoconstriction and decreased inflammatory cell migration reduce inflammation and itching.

💊 avoderm plus cream Uses in Hindi (Ke Fayde), Benefits & Indications

Tinea pedis, tinea cruris, tinea corporis with inflammatory symptoms.

Off-label uses: Seborrheic dermatitis, Psoriasis

⚠️ What are the side effects of avoderm plus cream?

✅ Common Side Effects

  • Application site irritation
  • Pruritus
  • Burning

🚨 Serious Side Effects

  • Skin atrophy
  • Hypothalamic-pituitary-adrenal axis suppression
  • Allergic contact dermatitis

⚠️ Rare Side Effects

  • Hypertrichosis
  • Perioral dermatitis
  • Acneiform eruptions

Consult your doctor if you experience any unusual symptoms.

🔄 Best Substitutes for avoderm plus cream

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Alternative medicines with exact same composition and strength (Terbinafine (1% w/w) + Clobetasol (0.05% w/w)):

  1. CANDID TOTAL CREAM
    Glenmark Pharmaceuticals LtdPrice Varies
  2. neo castor-nf cream
    Leeford Healthcare Ltd₹30.00💰 62.5% CHEAPER
  3. restoderm plus cream
    Dabur India Ltd₹32.92💰 58.9% CHEAPER
  4. total derm plus cream
    Alkem Laboratories Ltd₹44.55💰 44.3% CHEAPER
  5. coot ointment
    Cadila Pharmaceuticals Ltd₹45.00💰 43.8% CHEAPER
  6. tebif co2 cream
    Torrent Pharmaceuticals Ltd₹45.00💰 43.8% CHEAPER
  7. widerm cream
    Lupin Ltd₹47.00💰 41.3% CHEAPER
  8. clarex plus cream
    Concept Pharmaceuticals Ltd₹47.00💰 41.3% CHEAPER
  9. lamiterb plus cream
    Med Manor Organics Pvt Ltd₹47.30💰 40.9% CHEAPER
  10. bactromix cream
    Rhine Biogenics Pvt Ltd₹49.00💰 38.8% CHEAPER

Medical Note: Always consult your doctor before switching medications. Generic alternatives with same salts are therapeutically equivalent.

🔬 Drug Interactions

⚠️ Drug Severity Effect
CYP3A4 inhibitors Major Increased systemic exposure of clobetasol
CYP3A4 inducers Major Decreased efficacy of clobetasol
Warfarin Moderate Potential increased INR
Cyclosporine Moderate Increased risk of nephrotoxicity

🚨 Major Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole)
  • CYP3A4 inducers (e.g., rifampin)

⚡ Moderate Interactions

  • Warfarin
  • Cyclosporine

ℹ️ Minor Interactions

  • Antacids
  • Cimetidine

🍽️ Food Interactions

No significant food interactions for topical use.

🍷 Alcohol Interaction

No known interaction.

🛡️ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category C

🚫 Contraindications

Hypersensitivity to any component; viral skin infections (e.g., herpes); fungal nail infections (monotherapy).

📊 Monitoring Parameters

Skin improvement; signs of skin atrophy or systemic effects with prolonged use.

🤱 Lactation Safety

Use with caution; avoid application to breast area.

💊 Overdose Management

Unlikely with topical use; if ingested, symptomatic treatment.

⏰ Missed Dose

Apply as soon as remembered; skip if almost time for next dose.

🛑 Myths vs. Facts about avoderm plus cream

  • Myth: Generic substitutes of avoderm plus cream are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Terbinafine (1% w/w) + Clobetasol (0.05% w/w)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of avoderm plus cream can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

💬 Real Patient Experiences (Astitva)

Join Community

Read real stories and discussions from our patient community regarding similar health conditions.

Intermittent fasting se baal jhad rahe? 30 ki umar mein 50 jaisi ho gayi!

Aaj subah jab brush kiya toh haath mein baal ka guchha dekh ke ruk gaya. Seriously, I'm only 30 but lagta hai 50 ki ho gayi hoon. 6 months pehle maine intermittent fasting start kiya tha - 16:8, fir 18:6 bhi try kiya. Weight toh kuch nahi hua but hair fall bohot zyada ho gaya. Pehle toh maine socha stress hai, but phir pata chala ki fasting se nutrition deficiency ho sakti hai. Mummy roz bolti hain, "Beta itna diet karke kya karogi? Baal toh jhad rahe hain." Aur sahi keh rahi hain. Ab maine koi bhi diet nahi kiya, but weight bhi nahi gaya. Metabolism kharab ho chuka hai. Kal hi dermatologist ke paas gaya - vitamins check karwaye. Iron aur Vitamin D kam hai. Koi batao, kya intermittent fasting se hair fall hua hai kisi ko? Aur agar main ab normal khaana shuru kar doon toh kya yeh rukega? Ya fir koi specific supplements loon? Fed up ho gayi hoon apne aap se. Help karo yaar.

Bhai, relatives ka ghar ka nuskha aur acne ka frustration—kya karein? Koi dermatologist-approved product batao pls!

Bhai seriously ab bohot frustration ho raha hai. Kal mausi aayi thi ghar pe, aur bas face dekh ke bolne lagi "Oh beta yeh kya ho gaya? Itne bade pimple! Doodh me haldi aur besan laga kar raat ko laga lo." Like... ma'am I have tried every kitchen remedy since 10th standard. Nothing works. Mera acne cystic hai, dermatologist ne bhi kaha hai ki yeh hormonal hai, but relatives ko toh bas wahi ghar ke nuskhe bataane hain. Or sabse funny part yeh hai ki woh bolegi "Beta filter laga ke photo daalti ho na? Face toh dikhao asli." Hello?? Obviously main filter laga ke daalungi, face pe itne daag hai ki confidence hi nahi aata selfie lene ka. Pimple popping ki aadat bhi hai mujhe, I can't stop. Daag aur badh gaye hain. 🥲 Koi hai jo same situation me ho? Ya koi skincare product suggest karo jo acne ke daag kam kare? Please no home remedies, bas kuch dermatologist-approved batao. 🙏

Hormonal acne ne jawline ka kachra kar diya, shaadi ka proposal reject! 😭 Koi permanent solution?

Haan yaar, aaj toh bahut frustrate ho gayi. Hormonal acne ki wajah se meri jawline literally spotty ho gayi hai. Kal ek rishtedaar aaya tha shaadi ka proposal lekar, aur jaise hi mujhe dekha, woh directly "kya hua face pe?" bol diya. Aise toh confidence ka kachra ho jata hai. Main toh bas apne room mein ghus ke rone lagi. 😭 Iska koi permanent solution hai? Main derma se bhi dikha chuki hoon, woh kehte hain "hormones hain, time lagega". But time toh mera koi nahi hai—log reject kar rahe hain! Currently ek home remedy try kiya hai: neem ka paste + honey. Thoda soothing lagta hai but permanent toh nahi hai. Please koi batado, kya koi specific cream ya tablet hai jo jawline acne ke liye acha kaam kare? Ya phir koi diet change? Koi toh batao yaar, bahut bore ho gayi hoon. 😔

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