Auxen D 500mg/10mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Irregular heartbeat or palpitations
If experiencing severe symptoms, call emergency services immediately.
What is auxen d 500mg/10mg tablet used for?
This medicine is a combination of Naproxen (an NSAID) and Domperidone (an antiemetic) used to relieve pain and inflammation in conditions like arthritis, while reducing nausea and vomiting. It is taken orally with food, usually twice daily, and should not be used without a prescription.
- Generic Name: Naproxen + Domperidone
- Manufacturer: Aurum Life Science Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 auxen d 500mg/10mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा नेप्रोक्सन और डोम्पेरिडोन का संयोजन है, जिसका उपयोग दर्द और सूजन को कम करने के लिए किया जाता है, विशेष रूप से गठिया, जोड़ों के दर्द, और मांसपेशियों की समस्याओं में। यह मतली और उल्टी को भी रोकती है। इसे डॉक्टर की सलाह के बिना न लें।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट दर्द, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभावों में पेट में रक्तस्राव, अल्सर, गुर्दे की समस्या, दिल का दौरा, और एलर्जी प्रतिक्रियाएं शामिल हो सकती हैं। यदि आपको काला मल, खून की उल्टी, तेज पेट दर्द, सीने में दर्द, या सांस लेने में कठिनाई हो, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे भोजन या दूध के साथ लें ताकि पेट की जलन कम हो। शराब और धूम्रपान से बचें। यदि आपको चक्कर आते हैं या नींद आती है, तो वाहन न चलाएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। इसे बच्चों की पहुंच से दूर रखें।
💊 auxen d 500mg/10mg tablet Uses & Benefits
[{"condition":"Osteoarthritis","description":"Relieves pain, stiffness, and inflammation in joints affected by osteoarthritis, improving mobility.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Reduces joint pain, swelling, and tenderness associated with rheumatoid arthritis.","evidence":"Well-established"},{"condition":"Ankylosing spondylitis","description":"Helps alleviate back pain and stiffness in patients with ankylosing spondylitis.","evidence":"Well-established"},{"condition":"Acute musculoskeletal pain","description":"Provides short-term relief for acute pain from strains, sprains, and other musculoskeletal injuries.","evidence":"Well-established"},{"condition":"Dysmenorrhea","description":"Relieves menstrual cramps and associated pain.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine attacks due to its anti-inflammatory and antiemetic properties.","evidence":"Limited"},{"condition":"Postoperative pain","description":"May be used off-label for short-term management of postoperative pain and nausea.","evidence":"Limited"}]
Primary treatment for: Pain and inflammation associated with musculoskeletal and joint disorders.
Also treats: Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis, Dysmenorrhea, Acute musculoskeletal pain
📋 Drug Information
| Generic Name(s) | Naproxen + Domperidone |
| Brand Name | Auxen D 500mg/10mg Tablet |
| Manufacturer | Aurum Life Science Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID + Prokinetic agent |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a cool, dry place away from direct sunlight. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Naproxen reversibly inhibits cyclooxygenase enzymes (COX-1 and COX-2), leading to decreased synthesis of prostaglandins, which are mediators of pain, inflammation, and fever. Domperidone is a peripheral dopamine D2 receptor antagonist that blocks dopamine receptors in the chemoreceptor trigger zone and gastrointestinal tract, enhancing gastric emptying and reducing nausea and vomiting. The combination provides analgesic, anti-inflammatory, and antiemetic effects.
Mechanism Steps
💡 How to Take auxen d 500mg/10mg tablet
Strength: Naproxen 500 mg + Domperidone 10 mg immediate-release tablet.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally twice daily, preferably with food or milk. The dose may be adjusted by your doctor based on your condition and response. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding and kidney problems. Use with caution and lower doses may be considered. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose reduction may be necessary. Consult your doctor for appropriate dosing. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose reduction may be necessary. Consult your doctor for appropriate dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is 1000 mg of naproxen and 20 mg of domperidone (two tablets per day). Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of auxen d 500mg/10mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Other NSAIDs | Major | |
| Corticosteroids | Major | |
| ACE inhibitors | Major | |
| Lithium | Major | |
| Methotrexate | Major | |
| Diuretics | Moderate | |
| Beta-blockers | Moderate | |
| SSRIs | Moderate | |
| Ketoconazole | Moderate |
🚨 Major Interactions
- Warfarin
- Other NSAIDs
- Corticosteroids
- ACE inhibitors
- Lithium
- Methotrexate
⚡ Moderate Interactions
- Diuretics
- Beta-blockers
- SSRIs
- Ketoconazole
- Macrolide antibiotics
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding, ulcers, and liver problems. It may also worsen drowsiness and dizziness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Active peptic ulcer or history of recurrent ulcers","Severe heart failure","Severe liver impairment","Severe kidney impairment","Known allergy to naproxen, domperidone, or any component","History of asthma, urticaria, or allergic reaction to aspirin or other NSAIDs","Pregnancy (especially third trimester)","Breastfeeding","Children under 12 years","Prolactin-releasing pituitary tumor","Gastrointestinal obstruction or perforation"]
⚠️ Warnings & Precautions
["Take with food or milk to reduce stomach upset.","Avoid alcohol and smoking.","Do not drive or operate machinery if you feel dizzy or drowsy.","Inform your doctor if you have a history of ulcers, kidney or liver disease, heart problems, or asthma.","Do not take other NSAIDs or blood thinners without consulting your doctor.","Use with caution in the elderly due to increased risk of side effects.","Do not exceed the recommended dose or duration.","Consult your doctor if symptoms persist or worsen."]
🤱 Lactation Safety
Naproxen is excreted in breast milk in small amounts and is generally considered compatible with breastfeeding, but caution is advised. Domperidone is excreted in breast milk and may cause side effects in the infant. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose may cause severe nausea, vomiting, stomach pain, drowsiness, and gastrointestinal bleeding. Seek immediate medical attention. Treatment is supportive and symptomatic. Activated charcoal may be administered if within 1-2 hours of ingestion. Monitor vital signs and provide supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Take it with food or milk to reduce stomach upset. Avoid alcohol and smoking while on this medicine as they increase the risk of gastrointestinal bleeding. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Inform your doctor if you have a history of ulcers, kidney or liver disease, heart problems, or asthma. Do not take other NSAIDs or blood thinners without consulting your doctor. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before taking this medicine. Store in a cool, dry place away from direct sunlight and out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, kidney problems, and cardiovascular events. Use with caution, at the lowest effective dose, and monitor renal function and blood pressure regularly. Avoid long-term use unless necessary.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy, especially in the third trimester, due to risk of premature closure of the ductus arteriosus and other complications. If you are planning pregnancy, consult your doctor to discuss alternative pain relief options. Domperidone is also not recommended during pregnancy.
🏥 Post-Surgery Considerations
Use with caution after surgery, as NSAIDs can increase bleeding risk and impair wound healing. Consult your surgeon before taking this medicine. It may also interact with anesthetic agents. Inform your anesthesiologist about this medicine before any surgery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure, as it may increase bleeding risk. Your dentist may advise you to stop it temporarily before surgery. Do not stop without consulting your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid high-impact exercises that may strain joints. Consult your doctor or physiotherapist for an exercise plan tailored to your condition. Stop exercising if you experience severe pain, dizziness, or shortness of breath.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset, so take it with food. Inform your employer if your job involves operating machinery.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects like gastrointestinal bleeding, severe abdominal pain, or allergic reactions, stop the medicine and seek immediate medical attention. Your doctor will advise on the appropriate duration of treatment.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of gastrointestinal bleeding, ulcers, kidney problems, and cardiovascular events. Regular monitoring of kidney and liver function, blood counts, and blood pressure is recommended. Use the lowest effective dose for the shortest duration possible. Consult your doctor for periodic evaluations.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve joint function.
Evidence: Well-establishedMay help reduce pain and inflammation locally.
Evidence: LimitedSome evidence for pain relief in chronic conditions.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are established. However, if you are scheduled for vaccination, inform your healthcare provider about this medicine. There is no need to stop this medicine before vaccination unless advised by your doctor.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing times gradually as advised by your doctor. Check customs regulations for carrying prescription medicines. Keep enough supply for your trip and carry it in your hand luggage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Naproxen starts relieving pain within 1 hour, and domperidone reduces nausea within 30-60 minutes. However, full anti-inflammatory effects may take a few days.
A: No, it should be taken with food or milk to reduce the risk of stomach upset and ulcers.
A: Do not take other NSAIDs or painkillers without consulting your doctor, as it may increase the risk of side effects.
A: Follow your doctor's advice on the duration of treatment. Do not stop abruptly without consulting your doctor.
🤔 Common Patient Concerns
🔄 Substitutes for auxen d 500mg/10mg tablet
View AllAlternative brands with exact same active ingredient:
-
stayhappi naproxen+domperidone 500mg/10mg tabletSarvagunaushdhi Pvt Ltd ₹48.96 29.1% CHEAPER
-
xendom 500mg/10mg tabletZoic Lifesciences ₹64.69 6.3% CHEAPER
-
pandex tabletMission Research Laboratories Pvt Ltd ₹69.38 0.5% COSTLIER
-
naproxidim 500 tabletMSN Laboratories ₹70.00 1.4% COSTLIER
-
napuse 500mg/10mg tabletEvents Pharma ₹70.31 1.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Auxen D is a general painkiller for all types of pain.
Fact: Auxen D is specifically for inflammatory pain and is not recommended for all types of pain. It should be used only as prescribed. - Myth: Auxen D can be taken on an empty stomach.
Fact: Auxen D should be taken with food or milk to reduce the risk of stomach upset and ulcers. - Myth: Auxen D is safe to take with other painkillers.
Fact: Taking Auxen D with other NSAIDs can increase the risk of serious side effects. Always consult your doctor before combining medicines.
🔄 Alternative Options
Generic Alternatives
- Naproxen + Domperidone combination generics available
Brand Alternatives
- Auxen D 500mg/10mg tablet