Auxen D 250mg/10mg Tablet: Complete Information
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Irregular heartbeat or palpitations
If experiencing severe symptoms, call emergency services immediately.
What is auxen d 250mg/10mg tablet used for?
This medicine is a combination of Naproxen (an NSAID) and Domperidone (an antiemetic) used for relief of moderate to severe pain with nausea. It is taken orally with food, usually 2-3 times daily. It should be avoided in people with stomach ulcers, kidney or liver disease, or heart problems.
- Generic Name: Naproxen + Domperidone
- Manufacturer: Aurum Life Science Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 auxen d 250mg/10mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा नैप्रोक्सन और डोम्पेरिडोन का संयोजन है, जिसका उपयोग मध्यम से गंभीर दर्द और मतली के इलाज के लिए किया जाता है। यह मांसपेशियों के दर्द, मासिक धर्म के दर्द, और सर्जरी के बाद के दर्द में राहत देती है। इसे भोजन के साथ लेना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, पेट दर्द, सिरदर्द, चक्कर आना, और मुंह सूखना शामिल हैं। गंभीर दुष्प्रभावों में पेट में रक्तस्राव, गुर्दे की समस्या, और एलर्जी प्रतिक्रिया हो सकती है। यदि आपको काला मल, खून की उल्टी, या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे भोजन या दूध के साथ लें ताकि पेट में जलन न हो। शराब और अन्य दर्द निवारक दवाओं से बचें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं तो इसका उपयोग न करें। चक्कर आने पर वाहन न चलाएं। बच्चों की पहुंच से दूर रखें।
💊 auxen d 250mg/10mg tablet Uses & Benefits
[{"condition":"Musculoskeletal pain","description":"Relieves pain and inflammation in conditions such as osteoarthritis, rheumatoid arthritis, and back pain.","evidence":"Well-established"},{"condition":"Dysmenorrhea","description":"Reduces menstrual cramps and associated nausea.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Manages moderate to severe pain after surgery, especially when nausea is a concern.","evidence":"Moderate"},{"condition":"Migraine","description":"May help relieve migraine pain and associated nausea.","evidence":"Limited"}]
Off-label uses: [{"condition":"Gastroparesis","description":"Domperidone component may help with gastric emptying, but combination is not standard.","evidence":"Limited"}]
Primary treatment for: Musculoskeletal pain
Also treats: Dysmenorrhea, Post-operative pain, Migraine
📋 Drug Information
| Generic Name(s) | Naproxen + Domperidone |
| Brand Name | Auxen D 500mg/10mg Tablet |
| Manufacturer | Aurum Life Science Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID + Prokinetic agent |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Naproxen works by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), leading to decreased production of prostaglandins, which are mediators of pain, inflammation, and fever. Domperidone blocks dopamine D2 receptors in the chemoreceptor trigger zone and gastrointestinal tract, enhancing gastric motility and reducing nausea and vomiting.
Mechanism Steps
💡 How to Take auxen d 250mg/10mg tablet
Strength: Each tablet contains Naproxen 250 mg and Domperidone 10 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally two to three times daily, preferably with food. The exact dose and frequency depend on the condition being treated, its severity, and the patient's response. The maximum daily dose should not exceed 3 tablets in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients are at higher risk of side effects, especially gastrointestinal bleeding and kidney problems. Use the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with kidney impairment. Avoid in severe kidney disease (eGFR <30 mL/min). Dose adjustment may be needed. Consult a doctor. |
| Hepatic Impairment | Use with caution in patients with liver impairment. Avoid in severe liver disease. Dose adjustment may be needed. Consult a doctor. |
| Maximum Daily Dose | Maximum daily dose is 3 tablets (750 mg naproxen and 30 mg domperidone) in 24 hours. Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of auxen d 250mg/10mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Other NSAIDs | Major | |
| ACE inhibitors | Major | |
| Lithium | Major | |
| Methotrexate | Major | |
| Corticosteroids | Moderate | |
| Diuretics | Moderate | |
| SSRIs | Moderate | |
| Ketoconazole | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
- Other NSAIDs
- ACE inhibitors / ARBs
- Lithium
- Methotrexate
⚡ Moderate Interactions
- Corticosteroids
- Diuretics
- SSRIs
- Ketoconazole
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding, ulcers, and liver problems. It may also worsen dizziness and drowsiness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Active peptic ulcer or gastrointestinal bleeding","Severe kidney impairment (eGFR
⚠️ Warnings & Precautions
["Take with food to reduce stomach upset.","Avoid alcohol and other NSAIDs.","Do not use for more than 7 days without medical advice.","Use with caution in elderly patients.","May cause dizziness; avoid driving until you know how it affects you.","Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, or heart problems.","Do not take if you are pregnant or breastfeeding."]
🤱 Lactation Safety
Naproxen is excreted in breast milk in small amounts; domperidone is also excreted in breast milk. Use with caution and only if clearly needed. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose may cause severe nausea, vomiting, stomach pain, drowsiness, and kidney problems. Seek immediate medical attention. Treatment is supportive and symptomatic. Activated charcoal may be used if within 1-2 hours of ingestion. Monitor vital signs and kidney function.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not take more than the recommended dose or for longer than advised. Take it with food or milk to reduce stomach upset. Avoid alcohol and other NSAIDs while on this medicine. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart problems, or if you are pregnant or breastfeeding. Do not drive or operate heavy machinery if you feel dizzy. Keep out of reach of children. Store at room temperature away from moisture and heat. If you miss a dose, take it as soon as you remember unless it is almost time for the next dose; do not double the dose.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, kidney problems, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor kidney function and blood pressure regularly.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended if you are planning pregnancy or are pregnant. NSAIDs may affect ovulation and increase the risk of miscarriage. Consult your doctor for alternative pain relief options.
🏥 Post-Surgery Considerations
This medicine may be used for post-operative pain, but it can increase the risk of bleeding. Inform your surgeon if you are taking this medicine before any surgery. It may need to be stopped before surgery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. It may increase the risk of bleeding. Your dentist may advise stopping it temporarily.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or heavy lifting while on this medicine, especially if you experience dizziness or fatigue. Consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset, so take it with food. Most people can continue their daily activities with caution.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if you experience severe side effects such as gastrointestinal bleeding, allergic reactions, or kidney problems. Do not stop abruptly without consulting your doctor if you have been on long-term therapy.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of gastrointestinal bleeding, ulcers, kidney problems, and cardiovascular events. Regular monitoring of kidney function, liver function, and blood pressure is recommended. Use the lowest effective dose for the shortest duration.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain.
Evidence: Well-establishedMay help with pain relief.
Evidence: ModerateLocal application for pain relief.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. However, inform your doctor if you are scheduled for any vaccination while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for controlled substances; this medicine is not a controlled substance in most countries but carry documentation.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Pain relief usually starts within 30-60 minutes, and antiemetic effect within 30-60 minutes.
A: No, it should be taken with food or milk to reduce stomach upset.
A: It is not recommended during pregnancy, especially in the third trimester. Consult your doctor.
A: Avoid combining with other NSAIDs as it increases the risk of side effects. Consult your doctor.
🤔 Common Patient Concerns
🔄 Substitutes for auxen d 250mg/10mg tablet
View AllAlternative brands with exact same active ingredient:
-
stayhappi naproxen+domperidone 250mg/10mg tabletSarvagunaushdhi Pvt Ltd ₹32.29 31.1% CHEAPER
-
Spirox-D 250mg/10mg TabletKabir Life Sciences ₹39.84 15% CHEAPER
-
pacinac np 250mg/10mg tabletGentech Healthcare Pvt Ltd ₹42.19 10% CHEAPER
-
napuse 250mg/10mg tabletEvents Pharma ₹45.00 4% CHEAPER
-
vomigra 250mg/10mg tabletArwana Pharmaceuticals ₹48.75 4% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Auxen D is a simple painkiller with no risks.
Fact: It contains an NSAID and an antiemetic, and carries risks of gastrointestinal bleeding, kidney problems, and heart issues, especially with long-term use. - Myth: You can take Auxen D on an empty stomach.
Fact: It should be taken with food or milk to reduce stomach upset and risk of ulcers. - Myth: Auxen D is safe to take with other painkillers.
Fact: Combining with other NSAIDs increases the risk of side effects. Always consult a doctor.
🔄 Alternative Options
Generic Alternatives
- Naproxen + Domperidone combination (generic)
Brand Alternatives
- Auxen D 250mg/10mg tablet