atzaar 50mg tablet - Losartan (50mg) medicine

Atzaar 50mg Tablet - Uses, Price, Side Effects

4.5 (11 reviews)
๐Ÿญ Parenteral Drugs India Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 21, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 21, 2026

What is atzaar 50mg tablet used for?

Atzaar 50mg Tablet contains Losartan, an angiotensin II receptor blocker (ARB) used to treat high blood pressure and protect the kidneys in type 2 diabetes. It works by relaxing blood vessels, lowering blood pressure, and reducing strain on the heart.

  • Generic Name: Losartan
  • Manufacturer: Parenteral Drugs India Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š atzaar 50mg tablet Uses & Benefits

Hypertension, diabetic nephropathy, stroke prevention in hypertensive left ventricular hypertrophy.

Off-label uses: Heart failure, proteinuria, Marfan syndrome (aortic root dilation).

๐Ÿ“‹ Drug Information

Generic Name(s)Losartan
Brand NameAngizaar 50 Tablet
ManufacturerParenteral Drugs India Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassAngiotensin receptor blockers(ARB)
Route of AdministrationOral.
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally; absorption not affected by food.
DistributionDistributes widely; crosses blood-brain barrier poorly.
Protein Binding98.7% bound to plasma proteins, primarily albumin.
MetabolismHepatic metabolism via CYP2C9 and CYP3A4 to active metabolite E-3174.
Half-LifeLosartan: 2 hours; Active metabolite: 6-9 hours.
Excretion35% renal, 60% fecal.
Bioavailability33% (losartan); active metabolite has higher bioavailability.
Onset of Action1 hour.
Peak Plasma TimeLosartan: 1 hour; Active metabolite: 3-4 hours.
Duration of Action24 hours.

How It Works

Competitive antagonist of angiotensin II at AT1 receptor.

Mechanism Steps

1Losartan binds to AT1 receptor in vascular smooth muscle and adrenal gland.
2Blocks angiotensin II-mediated vasoconstriction and aldosterone secretion.
3Reduces peripheral vascular resistance and blood volume.

๐Ÿ’ก How to Take atzaar 50mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of atzaar 50mg tablet

โœ… Common Side Effects

  • Dizziness
  • Upper respiratory infection
  • Fatigue
  • Diarrhea
  • Hypotension

๐Ÿšจ Serious Side Effects

  • Angioedema
  • Hyperkalemia
  • Renal impairment
  • Hepatotoxicity

โš ๏ธ Rare Side Effects

  • Anaphylaxis
  • Pancreatitis
  • Rhabdomyolysis
  • Vasculitis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Potassium supplements Major Increased risk of hyperkalemia
Lithium Moderate Increased lithium toxicity
NSAIDs Moderate Reduced antihypertensive effect

๐Ÿšจ Major Interactions

  • Aliskiren
  • Lithium
  • Potassium-sparing diuretics
  • NSAIDs
  • Rifampin

โšก Moderate Interactions

  • ACE inhibitors
  • CYP2C9 inducers
  • CYP3A4 inhibitors

โ„น๏ธ Minor Interactions

  • Antacids
  • Digoxin
  • Warfarin

๐Ÿฝ๏ธ Food Interactions

No significant food interactions; avoid potassium-rich foods if hyperkalemia risk.

๐Ÿท Alcohol Interaction

May potentiate hypotensive effect; avoid excessive alcohol.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Moderate
Kidney
Moderate
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity, pregnancy (second/third trimesters), bilateral renal artery stenosis, concomitant aliskiren in diabetes.

๐Ÿ“Š Monitoring Parameters

Blood pressure, renal function, serum potassium, liver enzymes.

๐Ÿคฑ Lactation Safety

Not recommended; excreted in breast milk in animal studies.

๐Ÿ’Š Overdose Management

Symptomatic treatment; hypotension may require IV fluids and vasopressors.

โฐ Missed Dose

Take as soon as remembered; skip if near next dose. Do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for atzaar 50mg tablet

View All

Alternative brands with exact same active ingredient (Losartan (50mg)):

Medical Note: Always consult your doctor before switching medications.

โญ User Reviews

Certified Buyer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Certified Buyer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Trusted Reviewer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Verified User Jul 10, 2026

Found this to be a helpful product. Good results.

Verified User Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

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