bplosar 50 tablet

4.6 (10 reviews)

Losartan (50mg)

🏭 DR Best pharmaceuticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 21, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 21, 2026

What is bplosar 50 tablet used for?

Angizaar 50 Tablet (Losartan) is used to treat CARDIAC. It contains Losartan (50mg), which Competitive antagonist of angiotensin II at AT1 receptor.. Always consult your doctor before use. Take as prescribed.

Generic Name: Losartan
Manufacturer: DR Best pharmaceuticals Pvt Ltd
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 bplosar 50 tablet Uses & Benefits

Hypertension, diabetic nephropathy, stroke prevention in hypertensive left ventricular hypertrophy.

Off-label uses: Heart failure, proteinuria, Marfan syndrome (aortic root dilation).

📋 Drug Information

Generic Name(s)	Losartan
Brand Name	Angizaar 50 Tablet
Manufacturer	DR Best pharmaceuticals Pvt Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	CARDIAC
Action Class	Angiotensin receptor blockers(ARB)
Route of Administration	Oral.
Storage	Store at 20-25°C (68-77°F); protect from light and moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally; absorption not affected by food.

DistributionDistributes widely; crosses blood-brain barrier poorly.

Protein Binding98.7% bound to plasma proteins, primarily albumin.

MetabolismHepatic metabolism via CYP2C9 and CYP3A4 to active metabolite E-3174.

Half-LifeLosartan: 2 hours; Active metabolite: 6-9 hours.

Excretion35% renal, 60% fecal.

Bioavailability33% (losartan); active metabolite has higher bioavailability.

Onset of Action1 hour.

Peak Plasma TimeLosartan: 1 hour; Active metabolite: 3-4 hours.

Duration of Action24 hours.

How It Works

Competitive antagonist of angiotensin II at AT1 receptor.

Mechanism Steps

1Losartan binds to AT1 receptor in vascular smooth muscle and adrenal gland.

2Blocks angiotensin II-mediated vasoconstriction and aldosterone secretion.

3Reduces peripheral vascular resistance and blood volume.

💡 How to Take bplosar 50 tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of bplosar 50 tablet

✅ Common Side Effects

Dizziness
Upper respiratory infection
Fatigue
Diarrhea
Hypotension

🚨 Serious Side Effects

Angioedema
Hyperkalemia
Renal impairment
Hepatotoxicity

⚠️ Rare Side Effects

Anaphylaxis
Pancreatitis
Rhabdomyolysis
Vasculitis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Aliskiren	Major	Increased risk of hypotension, hyperkalemia, renal impairment
Lithium	Major	Increased lithium levels and toxicity
Potassium-sparing diuretics	Major	Hyperkalemia
NSAIDs	Major	Reduced antihypertensive effect, increased renal risk
Rifampin	Major	Decreased losartan efficacy
ACE inhibitors	Moderate	Additive hypotensive effect, hyperkalemia
CYP2C9 inducers	Moderate	Reduced losartan efficacy
CYP3A4 inhibitors	Moderate	Increased losartan levels
Antacids	Minor	Slight decrease in absorption
Digoxin	Minor	No significant interaction
Warfarin	Minor	No significant interaction

🚨 Major Interactions

Aliskiren
Lithium
Potassium-sparing diuretics
NSAIDs
Rifampin

⚡ Moderate Interactions

ACE inhibitors
CYP2C9 inducers
CYP3A4 inhibitors

ℹ️ Minor Interactions

Antacids
Digoxin
Warfarin

🍽️ Food Interactions

No significant food interactions; avoid potassium-rich foods if hyperkalemia risk.

🍷 Alcohol Interaction

May potentiate hypotensive effect; avoid excessive alcohol.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity, pregnancy (second/third trimesters), bilateral renal artery stenosis, concomitant aliskiren in diabetes.

📊 Monitoring Parameters

Blood pressure, renal function, serum potassium, liver enzymes.

🤱 Lactation Safety

Not recommended; excreted in breast milk in animal studies.

💊 Overdose Management

Symptomatic treatment; hypotension may require IV fluids and vasopressors.

⏰ Missed Dose

Take as soon as remembered; skip if near next dose. Do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

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🔄 Substitutes for bplosar 50 tablet

View All

Alternative brands with exact same active ingredient (Losartan (50mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Trusted Reviewer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.