bplosar 50 tablet - Losartan (50mg) medicine

Angizaar 50 Tablet (Losartan 50 mg): Complete Medicine Guide

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🏭 DR Best pharmaceuticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 16, 2026
⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category This medicine is contraindicated during pregnancy. It can cause harm or death to the developing fetus. Women who are pregnant or planning to become pregnant should not take this medicine and should contact their doctor immediately. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 16, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Swelling of the face, lips, throat, or tongue
  • Difficulty breathing or swallowing
  • Severe dizziness or fainting
  • Decreased urine output or swelling in legs
  • Irregular heartbeat or muscle weakness
  • Yellowing of skin or eyes
  • Severe abdominal pain with nausea or vomiting

If experiencing severe symptoms, call emergency services immediately.

What is bplosar 50 tablet used for?

This medicine is an angiotensin II receptor blocker (ARB) used to treat high blood pressure, protect kidneys in diabetes, and reduce stroke risk. It works by relaxing blood vessels. Take it once daily as prescribed.

  • Generic Name: Losartan
  • Manufacturer: DR Best pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 bplosar 50 tablet के बारे में (Hindi Summary)

उपयोग: यह दवा उच्च रक्तचाप (हाई ब्लड प्रेशर) को नियंत्रित करने के लिए इस्तेमाल की जाती है। यह मधुमेह रोगियों में गुर्दे की सुरक्षा करती है और स्ट्रोक का खतरा कम करती है। यह रक्त वाहिकाओं को आराम देकर रक्तचाप को कम करती है। इसे डॉक्टर के निर्देशानुसार रोज एक बार लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में चक्कर आना, सिरदर्द, थकान और पेट में हल्की परेशानी शामिल हैं। कभी-कभी एलर्जी, गुर्दे की समस्या या पोटैशियम का स्तर बढ़ सकता है। यदि सांस लेने में कठिनाई, चेहरे या गले में सूजन, या पेशाब कम आना हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे रोज एक ही समय पर लें। गर्भावस्था में इसका सेवन न करें। शराब का सेवन न करें क्योंकि इससे चक्कर आ सकते हैं। पोटैशियम युक्त नमक का इस्तेमाल बिना डॉक्टर की सलाह के न करें। यदि आपको चक्कर आते हैं तो वाहन न चलाएं। दवा बंद करने से पहले डॉक्टर से सलाह लें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 bplosar 50 tablet Uses & Benefits

[{"condition":"Hypertension","description":"This medicine is used to lower high blood pressure in adults, reducing the risk of heart attack, stroke, and kidney damage.","evidence":"Well-established"},{"condition":"Diabetic nephropathy","description":"This medicine helps protect kidney function in people with type 2 diabetes and high blood pressure by reducing protein leakage in urine.","evidence":"Well-established"},{"condition":"Stroke risk reduction in left ventricular hypertrophy","description":"This medicine is used to reduce the risk of stroke in patients with high blood pressure and an enlarged heart muscle.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Heart failure","description":"Sometimes used as part of heart failure treatment when other medicines are not tolerated.","evidence":"Limited"},{"condition":"Marfan syndrome","description":"Occasionally prescribed to slow aortic enlargement in people with Marfan syndrome.","evidence":"Limited"}]

Primary treatment for: Hypertension

Also treats: Diabetic nephropathy, Left ventricular hypertrophy, Heart failure (off-label)

📋 Drug Information

Generic Name(s)Losartan
Brand NameAngizaar 50 Tablet
ManufacturerDR Best pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassAngiotensin receptor blockers(ARB)
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain consistent blood pressure control.
2
Monitor your blood pressure regularly and keep a record to share with your doctor.
3
Avoid potassium supplements and salt substitutes unless approved by your doctor.
4
Stay hydrated, especially during hot weather or exercise, to prevent low blood pressure.
5
Inform your doctor if you experience dizziness, especially when standing up.
6
Do not stop this medicine abruptly without consulting your doctor.
7
If you are planning pregnancy, discuss alternative treatments with your doctor.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High blood pressure
This medicine is commonly prescribed for this.
Likely Use
✅
Protein in urine due to diabetes
This medicine helps protect kidneys.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is well absorbed from the gastrointestinal tract after oral administration. The absolute bioavailability is approximately 33%.
DistributionThis medicine is distributed into most body tissues. It crosses the placental barrier and is present in breast milk in small amounts.
Protein BindingThis medicine is highly bound to plasma proteins, primarily albumin, with a binding rate of about 98.7%.
MetabolismThis medicine undergoes extensive first-pass metabolism in the liver. It is metabolized by cytochrome P450 enzymes, primarily CYP2C9 and CYP3A4, into an active metabolite (E-3174) which is 10 to 40 times more potent than the parent compound.
Half-LifeThe elimination half-life of this medicine is approximately 2 hours, and that of its active metabolite is about 6 to 9 hours.
ExcretionThis medicine and its metabolites are excreted primarily in the urine (about 35%) and feces (about 60%) as unchanged drug and metabolites.
BioavailabilityThe oral bioavailability of this medicine is approximately 33%.
Onset of ActionThe blood pressure-lowering effect begins within 1 to 2 hours after oral administration, but the full therapeutic effect may take 3 to 6 weeks of regular use.
Peak Plasma TimePeak plasma concentrations of this medicine are reached about 1 hour after oral administration, and peak concentrations of its active metabolite are reached in 3 to 4 hours.
Duration of ActionThe blood pressure-lowering effect of a single dose lasts for about 24 hours, allowing once-daily dosing.

How It Works

This medicine works by selectively blocking the angiotensin II type 1 (AT1) receptor. Angiotensin II is a hormone that constricts blood vessels and stimulates the release of aldosterone, which causes salt and water retention. By blocking the AT1 receptor, this medicine prevents these effects, leading to relaxation of blood vessels, reduced blood pressure, and decreased aldosterone release. This results in less sodium and water retention and a lower workload on the heart.

Mechanism Steps

1
Binding to AT1 receptor: This medicine binds selectively to the angiotensin II type 1 receptor, preventing angiotensin II from attaching to it.
2
Blockade of vasoconstriction: By blocking the receptor, this medicine prevents the tightening of blood vessels that angiotensin II would normally cause.
3
Reduced aldosterone release: The blockade leads to decreased secretion of aldosterone, which reduces sodium and water retention and lowers potassium excretion.
4
Lower blood pressure: The combined effects of vasodilation and reduced fluid retention result in a decrease in blood pressure.

💡 How to Take bplosar 50 tablet

Strength: Losartan 50 mg immediate-release tablet.

1Take this medicine by mouth with or without food.
2Swallow the tablet whole with a glass of water.
3Take it at the same time each day to maintain consistent levels.
4Do not crush, chew, or break the tablet unless your doctor advises.
5If you miss a dose, follow the missed dose instructions.
6Do not stop taking this medicine without consulting your doctor.

Dosage Information

Adult DosageThe usual starting dose of this medicine for high blood pressure is 50 mg once daily. Your doctor may increase the dose to 100 mg once daily if needed. For diabetic nephropathy, the usual dose is 50 mg once daily, which may be increased to 100 mg once daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo specific dose adjustment is required for elderly patients, but they may be more sensitive to the blood pressure-lowering effects. Start with a lower dose and monitor closely.
Renal ImpairmentNo initial dose adjustment is needed for mild to moderate renal impairment. For severe renal impairment or dialysis patients, consult a doctor for dose adjustment.
Hepatic ImpairmentFor patients with mild to moderate hepatic impairment, a lower starting dose is recommended. Use with caution in severe hepatic impairment.
Maximum Daily Dose100 mg per day.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With or without food
Take at the same time daily
Food does not significantly affect absorption.
High-potassium foods
Moderate intake
This medicine can raise potassium levels.
Grapefruit juice
Limit
May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours have passed since the missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 12 hours have passed since the missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of bplosar 50 tablet

✅ Common Side Effects

Dizziness (Common (5-10%))
Rise slowly from sitting or lying positions. If dizziness persists or is severe, consult your doctor.
Headache (Common (5-10%))
Usually resolves on its own. If it continues, talk to your doctor about pain relief options.
Tiredness (Common (5-10%))
Ensure adequate rest. If fatigue interferes with daily activities, consult your doctor.
Stomach discomfort (Uncommon (1-5%))
Take with food to reduce stomach upset. If it persists, seek medical advice.

🚨 Serious Side Effects

Severe allergic reaction (angioedema) (Rare (<0.1%))
Seek immediate medical attention if you notice swelling of the face, lips, throat, or tongue, or difficulty breathing.
Kidney problems (Rare (<0.1%))
Contact your doctor if you experience decreased urine output, swelling in legs, or unusual fatigue.
High potassium levels (hyperkalemia) (Uncommon (1-5%))
Report muscle weakness, irregular heartbeat, or numbness to your doctor promptly.
Low blood pressure (hypotension) (Uncommon (1-5%))
If you feel faint or dizzy, lie down and contact your doctor. Avoid driving until you feel better.

⚠️ Rare Side Effects

Liver enzyme elevation
Report yellowing of skin or eyes, dark urine, or severe abdominal pain to your doctor immediately.
Low white blood cell count
If you develop frequent infections, fever, or sore throat, seek medical attention.
Rhabdomyolysis
Seek immediate care if you experience severe muscle pain, weakness, or dark urine.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Spironolactone Major
Lithium Major
Ibuprofen Major
Rifampin Moderate
Fluconazole Moderate
Amlodipine Moderate
Antacids Minor
Grapefruit juice Minor

🚨 Major Interactions

  • Potassium-sparing diuretics (e.g., spironolactone, triamterene)
  • Potassium supplements
  • Lithium
  • Nonsteroidal anti-inflammatory drugs (NSAIDs)

⚡ Moderate Interactions

  • Rifampin
  • Fluconazole
  • Other blood pressure medicines

🍷 Alcohol Interaction

Alcohol can enhance the blood pressure-lowering effect of this medicine and may cause dizziness or fainting. It is advisable to limit or avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Pregnancy","Severe allergic reaction to losartan or any ARB","Bilateral renal artery stenosis","Severe liver impairment","Concomitant use with aliskiren in patients with diabetes"]

⚠️ Warnings & Precautions

["Avoid use during pregnancy; can cause fetal harm.","Monitor potassium levels, especially in patients with kidney disease or diabetes.","May cause dizziness; avoid driving until you know how it affects you.","Do not use potassium supplements or salt substitutes without doctor's approval.","Use with caution in patients with liver or kidney disease.","Inform your doctor if you have a history of angioedema.","May cause low blood pressure in patients who are volume-depleted."]

🤱 Lactation Safety

This medicine is present in breast milk in small amounts. It is generally considered safe during breastfeeding, but consult your doctor to weigh the benefits and risks.

💊 Overdose Management

Overdose may cause severe low blood pressure and dizziness. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and may include intravenous fluids and monitoring of vital signs.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor, usually once daily, with or without food. Do not change the dose or stop taking it without consulting your clinician. Because this medicine can cause dizziness, avoid driving or operating heavy machinery until you know how it affects you. Drink enough water to stay hydrated, especially in hot weather or during exercise. Avoid salt substitutes that contain potassium unless your doctor approves them, as this medicine can raise potassium levels. Inform all your healthcare providers that you are taking this medicine, especially before surgery or dental procedures. Do not take this medicine if you are pregnant or planning to become pregnant. If you miss a dose, follow your doctor's instructions and never double the dose to catch up.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the blood pressure-lowering effects of this medicine. Start with a lower dose and monitor blood pressure regularly to avoid falls.

🤰 Pregnancy Planning (TTC)

This medicine is contraindicated during pregnancy. If you are planning pregnancy, consult your doctor to switch to a safer alternative before conception.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be temporarily stopped before surgery to avoid low blood pressure during the procedure.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine. It may cause dry mouth or dizziness during dental procedures. Maintain good oral hygiene.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to help control blood pressure.
🥗
Engage in regular physical activity like walking or swimming.
😴
Reduce salt intake to enhance blood pressure control.
💧
Avoid smoking and limit alcohol consumption.
🧘
Manage stress through relaxation techniques like yoga or meditation.
🌞
Get adequate sleep to support overall health.

🏋️ Exercise Considerations

This medicine may cause dizziness, especially during initial treatment or when standing up quickly. Avoid strenuous exercise until you know how the medicine affects you. Stay hydrated during exercise.

🥗 Diet Recommendations

Follow a low-sodium diet (DASH diet).
Include potassium-rich foods in moderation, but avoid excessive intake.
Limit processed foods and added sugars.
Eat plenty of fruits, vegetables, and whole grains.
Stay well hydrated with water.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or tiredness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. Most people can continue their normal work routine with dose adjustments.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience serious side effects or are planning pregnancy, contact your doctor immediately to discuss alternative treatments.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe and effective for managing high blood pressure and protecting kidneys. Regular monitoring of blood pressure, kidney function, and potassium levels is recommended. Do not stop the medicine without medical advice, as abrupt discontinuation can lead to rebound hypertension.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet, exercise, and weight loss can help lower blood pressure and complement medicine.

Evidence: Well-established
Other antihypertensive classes

ACE inhibitors, calcium channel blockers, or diuretics may be alternatives if this medicine is not suitable.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. Continue routine vaccinations as recommended by your doctor.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing times gradually under medical guidance. Keep enough supply for the entire trip and carry a list of your medications. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with high blood pressure and type 2 diabetes
He was prescribed this medicine 50 mg once daily to control blood pressure and protect his kidneys. After 3 months, his blood pressure was well controlled, and urine protein levels decreased. He experienced mild dizziness initially, which resolved after a few days.
💡 Lesson: Regular monitoring and adherence to prescribed dose can lead to significant kidney protection in diabetes.
👤 A 62-year-old woman with hypertension and left ventricular hypertrophy
She started this medicine 50 mg daily and later increased to 100 mg. Her blood pressure normalized, and her risk of stroke was reduced. She learned to avoid salt substitutes and to monitor her potassium levels.
💡 Lesson: Lifestyle modifications and regular follow-ups are essential for optimal outcomes with this medicine.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts lowering blood pressure within 1-2 hours, but full effects may take 3-6 weeks of regular use.

Q: Can I take this medicine with food?

A: Yes, this medicine can be taken with or without food. Taking it at the same time daily is important.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Is this medicine safe during pregnancy?

A: No, this medicine is contraindicated during pregnancy as it can harm the fetus. Consult your doctor immediately if you become pregnant.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my other blood pressure medicines?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for bplosar 50 tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be stopped once blood pressure is normal.
    Fact: High blood pressure often has no symptoms, and stopping this medicine can cause a dangerous rise in blood pressure. Continue as prescribed.
  • Myth: This medicine causes kidney damage.
    Fact: This medicine actually protects kidneys in people with diabetes and high blood pressure. Regular monitoring is important.
  • Myth: This medicine is safe to take during pregnancy.
    Fact: This medicine is contraindicated during pregnancy as it can harm the fetus.

🔄 Alternative Options

Generic Alternatives

  • Losartan potassium 50 mg tablet

Brand Alternatives

  • Angizaar 50 tablet

📊 Comparison with Similar Medicines

[{"medicine":"Losartan","class":"ARB","half_life":"2 hours (active metabolite 6-9 hours)","usual_dose":"50-100 mg once daily"},{"medicine":"Valsartan","class":"ARB","half_life":"6 hours","usual_dose":"80-320 mg once daily"},{"medicine":"Telmisartan","class":"ARB","half_life":"24 hours","usual_dose":"40-80 mg once daily"}]

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