atromend-gold capsule - Uses, Price, Side Effects & Substitutes
What is atromend-gold capsule used for?
Aztogold 20 Capsule (Aspirin + Atorvastatin) is used to treat CARDIAC. It contains Aspirin (75mg) + Atorvastatin (10mg), which Aspirin irreversibly inhibits COX-1, reducing thromboxane A2 and platelet aggreg. Always consult your doctor before use. Take as prescribed.
- Generic Name: Aspirin + Atorvastatin
- Manufacturer: Mendcure Life Sciences Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ atromend-gold capsule Uses & Benefits
Secondary prevention of cardiovascular events, hypercholesterolemia, coronary artery disease
Off-label uses: Primary prevention in high-risk patients, prevention of preeclampsia (low-dose aspirin)
๐ Drug Information
| Generic Name(s) | Aspirin + Atorvastatin |
| Brand Name | Aztogold 20 Capsule |
| Manufacturer | Mendcure Life Sciences Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Antiplatelet + HMG-CoA Reductase Inhibitor |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Aspirin irreversibly inhibits COX-1, reducing thromboxane A2 and platelet aggregation; Atorvastatin inhibits HMG-CoA reductase, reducing cholesterol synthesis
Mechanism Steps
๐ก How to Take atromend-gold capsule
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of atromend-gold capsule
โ Common Side Effects
- Dyspepsia
- Nausea
- Diarrhea
- Headache
- Muscle pain
๐จ Serious Side Effects
- GI bleeding
- Rhabdomyolysis
- Hepatotoxicity
- Stroke (hemorrhagic)
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Thrombocytopenia
- Pancreatitis
- Interstitial nephritis
- Angioedema
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Methotrexate | Major | Increased methotrexate toxicity |
| Clopidogrel | Major | Increased bleeding risk |
| Ciclosporin | Major | Increased atorvastatin levels |
| Gemfibrozil | Major | Increased risk of myopathy/rhabdomyolysis |
| NSAIDs | Moderate | Increased GI bleeding risk |
| Antacids | Moderate | Reduced aspirin absorption |
| Digoxin | Moderate | Increased digoxin levels |
| Oral contraceptives | Moderate | Reduced contraceptive efficacy |
| Macrolide antibiotics | Moderate | Increased atorvastatin levels |
| Vitamin E | Minor | Increased bleeding risk |
| Ginkgo biloba | Minor | Increased bleeding risk |
| Alcohol | Minor | Increased GI bleeding risk |
๐จ Major Interactions
- Warfarin
- Methotrexate
- Clopidogrel
- Ciclosporin
- Gemfibrozil
โก Moderate Interactions
- NSAIDs
- Antacids
- Digoxin
- Oral contraceptives
- Macrolide antibiotics
โน๏ธ Minor Interactions
- Vitamin E
- Ginkgo biloba
- Alcohol
๐ฝ๏ธ Food Interactions
Grapefruit juice increases atorvastatin levels; food delays aspirin absorption
๐ท Alcohol Interaction
Increased risk of GI bleeding
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Active peptic ulcer, hemophilia, severe hepatic impairment, pregnancy, lactation, hypersensitivity to any component
๐ Monitoring Parameters
Lipid profile, liver function tests, INR (if on warfarin), renal function, signs of bleeding
๐คฑ Lactation Safety
Contraindicated; atorvastatin excreted in milk
๐ Overdose Management
Gastric lavage, activated charcoal, supportive care; for aspirin toxicity: alkalinization, hemodialysis
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose; do not double