Atromend-AS 20/150 Capsule - Uses, Price, Side Effects, Interactions
What is atromend-as 20/150 capsule used for?
Atromend-AS 20/150 capsule is a combination of Atorvastatin (20mg) and Aspirin (150mg) used to reduce the risk of heart attack and stroke in patients with cardiovascular disease. Atorvastatin lowers cholesterol, while Aspirin prevents blood clots. It is typically taken once daily in the morning.
- Generic Name: Atorvastatin + Aspirin
- Manufacturer: Mendcure Life Sciences Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ atromend-as 20/150 capsule Uses & Benefits
Primary and secondary prevention of cardiovascular events in patients with hyperlipidemia and at risk of thrombotic events.
Off-label uses: Not applicable.
๐ Drug Information
| Generic Name(s) | Atorvastatin + Aspirin |
| Brand Name | Aztor Asp 75 Capsule |
| Manufacturer | Mendcure Life Sciences Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | HMG-CoA Reductase Inhibitor + Antiplatelet Agent |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture and light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Atorvastatin: Inhibits HMG-CoA reductase, reducing cholesterol synthesis; Aspirin: Irreversibly inhibits cyclooxygenase (COX-1), reducing thromboxane A2 production and platelet aggregation.
Mechanism Steps
๐ก How to Take atromend-as 20/150 capsule
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of atromend-as 20/150 capsule
โ Common Side Effects
- Headache
- Dizziness
- Nausea
- Diarrhea
- Muscle pain
- Dyspepsia
- Increased liver enzymes
๐จ Serious Side Effects
- Rhabdomyolysis
- Hepatotoxicity
- Gastrointestinal bleeding
- Hemorrhagic stroke
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Myopathy
- Pancreatitis
- Thrombocytopenia
- Interstitial lung disease
- Anaphylaxis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Clopidogrel | Moderate | Increased risk of bleeding |
| Methotrexate | Major | Increased methotrexate toxicity |
| NSAIDs | Moderate | Increased risk of gastrointestinal bleeding |
| Antacids | Minor | Reduced absorption of atorvastatin |
๐จ Major Interactions
- Warfarin
- Ciclosporin
- Clarithromycin
- Itraconazole
- HIV protease inhibitors
- Methotrexate
โก Moderate Interactions
- Digoxin
- Oral contraceptives
- Colchicine
- Antacids
- Fibrates
- Niacin
โน๏ธ Minor Interactions
- Grapefruit juice
- Vitamin K antagonists (low dose)
- Spironolactone
๐ฝ๏ธ Food Interactions
Grapefruit juice increases atorvastatin levels; avoid high-fat meals with aspirin.
๐ท Alcohol Interaction
Increased risk of gastrointestinal bleeding with aspirin; alcohol may affect atorvastatin metabolism.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Active liver disease, unexplained persistent liver enzyme elevations, pregnancy, breastfeeding, active peptic ulcer, bleeding disorders, hypersensitivity to any component.
๐ Monitoring Parameters
Liver function tests, lipid profile, renal function, signs of bleeding, INR if on warfarin.
๐คฑ Lactation Safety
Atorvastatin: Not recommended; Aspirin: Excreted in breast milk, avoid high doses.
๐ Overdose Management
Symptomatic and supportive care; for aspirin overdose, consider gastric lavage, activated charcoal, and hemodialysis in severe cases.
โฐ Missed Dose
Take as soon as remembered unless close to next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
This medicine was effective for me. I followed the doctor's advice.
This medicine was effective for me. I followed the doctor's advice.
Effective and reliable. Worked as expected.
Effective and reliable. Worked as expected.
This medicine was effective for me. I followed the doctor's advice.