atext 12.5mg tablet pr - Paroxetine (12.5mg) medicine

Atext 12.5mg Tablet PR - Uses, Price, Side Effects

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๐Ÿญ Atral Cyrus Lifesciences ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is atext 12.5mg tablet pr used for?

Atext 12.5mg Tablet PR contains Paroxetine, a selective serotonin reuptake inhibitor (SSRI) used to treat depression, anxiety disorders, obsessive-compulsive disorder (OCD), and panic attacks. It works by increasing serotonin levels in the brain, improving mood and reducing anxiety.

  • Generic Name: Paroxetine
  • Manufacturer: Atral Cyrus Lifesciences
  • Form: Allopathy
  • Pregnancy Category: D
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š atext 12.5mg tablet pr Uses & Benefits

Major depressive disorder, obsessive-compulsive disorder, panic disorder, social anxiety disorder, generalized anxiety disorder, post-traumatic stress disorder.

Off-label uses: Premenstrual dysphoric disorder, hot flashes, premature ejaculation.

๐Ÿ“‹ Drug Information

Generic Name(s)Paroxetine
Brand NameAroximat CR 12.5 Tablet
ManufacturerAtral Cyrus Lifesciences
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassSelective Seretonin Reuptake inhibitors (SSRIs)
Route of AdministrationOral.
StorageStore at 20-25ยฐC (68-77ยฐF); protect from moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed from the gastrointestinal tract; food does not significantly affect absorption.
DistributionWidely distributed in the body; crosses the blood-brain barrier.
Protein BindingApproximately 95% bound to plasma proteins.
MetabolismExtensively metabolized in the liver via CYP2D6 and other enzymes.
Half-LifeAbout 21 hours (range 3-65 hours).
ExcretionPrimarily excreted in urine (64%) and feces (36%).
BioavailabilityAbout 50-100% (mean 86%).
Onset of Action1-2 weeks for therapeutic effect.
Peak Plasma Time5-6 hours (controlled-release formulation).
Duration of Action24 hours.

How It Works

Selective serotonin reuptake inhibitor (SSRI); increases serotonin levels in the synaptic cleft.

Mechanism Steps

1Paroxetine binds to the serotonin transporter (SERT) on presynaptic neurons.
2Inhibits reuptake of serotonin into the presynaptic neuron.
3Increases serotonin concentration in the synaptic cleft.

๐Ÿ’ก How to Take atext 12.5mg tablet pr

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of atext 12.5mg tablet pr

โœ… Common Side Effects

  • Nausea
  • Drowsiness
  • Dizziness
  • Insomnia
  • Dry mouth
  • Constipation
  • Sexual dysfunction

๐Ÿšจ Serious Side Effects

  • Serotonin syndrome
  • Suicidal thoughts
  • Bleeding
  • Seizures
  • Hyponatremia

โš ๏ธ Rare Side Effects

  • Priapism
  • Angle-closure glaucoma
  • Stevens-Johnson syndrome

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
MAOIs Major Increased risk of serotonin syndrome
Warfarin Moderate Increased bleeding risk
Alcohol Moderate Increased CNS depression

๐Ÿšจ Major Interactions

  • MAOIs
  • Pimozide
  • Thioridazine
  • Linezolid
  • Methylene Blue

โšก Moderate Interactions

  • Warfarin
  • NSAIDs
  • Aspirin
  • Cimetidine
  • Flecainide
  • Propafenone
  • Tamoxifen

โ„น๏ธ Minor Interactions

  • Digoxin
  • Theophylline
  • Lithium

๐Ÿฝ๏ธ Food Interactions

Grapefruit juice may increase paroxetine levels.

๐Ÿท Alcohol Interaction

Avoid alcohol; may increase CNS depression.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Moderate
Kidney
Low
Heart
Low
Pregnancy
Category D

๐Ÿšซ Contraindications

Hypersensitivity, concurrent MAOI use, pregnancy (especially third trimester), lactation.

๐Ÿ“Š Monitoring Parameters

Suicidal ideation, serotonin syndrome symptoms, liver function, renal function.

๐Ÿคฑ Lactation Safety

Not recommended; excreted in breast milk.

๐Ÿ’Š Overdose Management

Activated charcoal, supportive care; serotonin syndrome management.

โฐ Missed Dose

Take as soon as remembered unless near next dose; skip if close.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for atext 12.5mg tablet pr

View All

Alternative brands with exact same active ingredient (Paroxetine (12.5mg)):

Medical Note: Always consult your doctor before switching medications.

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