asvs polyvalent injection - Hemocoagulase (NA) medicine

asvs polyvalent injection

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🏭 Serum Institute Of India Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

What is asvs polyvalent injection used for?

This medicine contains Hemocoagulase (NA) and is used to treat BLOOD RELATED. Hemocoagulase acts as a procoagulant by converting fibrinogen to fibrin, promoting clot formation an. Always consult your doctor before use.

  • Generic Name: Hemocoagulase
  • Manufacturer: Serum Institute Of India Ltd
  • Form: Allopathy
  • Pregnancy Category: Category A
  • Prescription Required: Yes
💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 asvs polyvalent injection Uses & Benefits

Snakebite envenomation with bleeding, hemorrhage control, surgical bleeding.

Off-label uses: Hemophilia, von Willebrand disease (limited evidence).

📋 Drug Information

Generic Name(s)Hemocoagulase
Brand NameAnti Snake Injection
ManufacturerSerum Institute Of India Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassBLOOD RELATED
Action ClassHaemostatic agent
Route of AdministrationIntravenous, Intramuscular
StorageStore at 2-8°C; protect from light.
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionNot applicable; administered intravenously or intramuscularly.
DistributionDistributed in blood and tissues; binds to fibrinogen.
Protein BindingNot specified
MetabolismMetabolized by proteolytic degradation.
Half-LifeApproximately 3-6 hours
ExcretionExcreted via urine and feces as metabolites.
Bioavailability100% (intravenous)
Onset of ActionImmediate (within minutes)
Peak Plasma TimeNot applicable; immediate effect.
Duration of Action4-6 hours

How It Works

Hemocoagulase acts as a procoagulant by converting fibrinogen to fibrin, promoting clot formation and hemostasis.

Mechanism Steps

1Hemocoagulase binds to fibrinogen.
2Converts fibrinogen to fibrin monomers.
3Fibrin monomers polymerize to form a clot.
4Clot stabilizes and reduces bleeding.

💡 How to Take asvs polyvalent injection

Follow your doctor's prescription exactly.

⚠️ Side Effects of asvs polyvalent injection

✅ Common Side Effects

Injection site pain
Bruising
Nausea

🚨 Serious Side Effects

Thrombosis
Allergic reactions
Anaphylaxis

⚠️ Rare Side Effects

Disseminated intravascular coagulation
Hypotension

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major Increased bleeding risk
Heparin Major Increased bleeding risk
Aspirin Major Increased bleeding risk
Clopidogrel Major Increased bleeding risk
Alteplase Moderate Reduced efficacy of thrombolysis
Ibuprofen Moderate Increased bleeding risk
Ginkgo biloba Minor Additive anticoagulant effect

🚨 Major Interactions

  • Anticoagulants (e.g., Warfarin, Heparin)
  • Antiplatelet agents (e.g., Aspirin, Clopidogrel)

⚡ Moderate Interactions

  • Thrombolytics (e.g., Alteplase)
  • Nonsteroidal anti-inflammatory drugs (NSAIDs)

🍷 Alcohol Interaction

May increase bleeding risk; avoid alcohol.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to hemocoagulase, active thrombosis, disseminated intravascular coagulation (DIC).

🤱 Lactation Safety

Not recommended; excretion in breast milk unknown.

💊 Overdose Management

Monitor for thrombosis; supportive care; consider anticoagulants if needed.

⏰ Missed Dose

Not applicable; administered as needed.

🔄 Substitutes for asvs polyvalent injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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