Abvida-m 50mg/500mg Eazy Glide Tablet: Complete Information
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Rapid breathing or shortness of breath
- Severe muscle pain or cramps
- Persistent stomach pain with nausea or vomiting
- Signs of allergic reaction: rash, itching, swelling of face/lips/tongue
- Yellowing of skin or eyes
- Dark urine or decreased urine output
- Severe abdominal pain radiating to the back
If experiencing severe symptoms, call emergency services immediately.
What is astroglip m 500mg/50mg tablet used for?
This medicine is a combination of Metformin and Vildagliptin used to treat type 2 diabetes. It helps control blood sugar by improving insulin sensitivity and increasing insulin release after meals. It is taken orally twice daily with food.
- Generic Name: Metformin + Vildagliptin
- Manufacturer: Astorion Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 astroglip m 500mg/50mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा टाइप 2 डायबिटीज (मधुमेह) के इलाज के लिए इस्तेमाल की जाती है। यह मेटफॉर्मिन और विल्डाग्लिप्टिन का संयोजन है, जो रक्त शर्करा को नियंत्रित करने में मदद करता है। यह इंसुलिन की कार्यक्षमता को बढ़ाता है और भोजन के बाद इंसुलिन के स्राव को बढ़ाता है। इसे भोजन के साथ दिन में दो बार लिया जाता है।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, दस्त, पेट में परेशानी, सिरदर्द और चक्कर आना शामिल हैं। गंभीर दुष्प्रभावों में लैक्टिक एसिडोसिस, अग्नाशयशोथ, और एलर्जी प्रतिक्रियाएं हो सकती हैं। यदि आपको तेजी से सांस लेने, मांसपेशियों में दर्द, या पेट में तेज दर्द हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक न बढ़ाएं और न ही छोड़ें। शराब का सेवन न करें क्योंकि इससे लैक्टिक एसिडोसिस का खतरा बढ़ सकता है। नियमित रूप से ब्लड शुगर की जांच करें। संतुलित आहार और व्यायाम करें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें।
💊 astroglip m 500mg/50mg tablet Uses & Benefits
[{"condition":"Type 2 Diabetes Mellitus","description":"Improves glycemic control in adults when Metformin alone or Vildagliptin alone does not achieve target HbA1c levels.","evidence":"Well-established"}]
Off-label uses: []
Primary treatment for: Type 2 Diabetes Mellitus
Also treats: Obesity, Metabolic syndrome, Polycystic ovary syndrome (off-label)
📋 Drug Information
| Generic Name(s) | Metformin + Vildagliptin |
| Brand Name | Abvida-M 50mg/500mg Eazy Glide Tablet |
| Manufacturer | Astorion Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI DIABETIC |
| Action Class | ANTI DIABETIC |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antidiabetic agents with complementary mechanisms. Metformin decreases hepatic glucose production, reduces intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization. Vildagliptin inhibits dipeptidyl peptidase-4 (DPP-4), thereby increasing the levels of active incretin hormones (GLP-1 and GIP), which stimulate insulin release from pancreatic beta cells and reduce glucagon secretion from alpha cells. The combined effect leads to better postprandial and fasting glucose control.
Mechanism Steps
💡 How to Take astroglip m 500mg/50mg tablet
Strength: Immediate-release tablet containing Metformin 500 mg and Vildagliptin 50 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally twice daily with meals. The dose may be adjusted by your doctor based on your blood sugar levels and kidney function. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require dose adjustment based on renal function. Monitor renal function regularly. Start with a lower dose if renal impairment is present. |
| Renal Impairment | Assess renal function before initiating and at least annually. If eGFR is 30-45 mL/min/1.73 m², start with caution and monitor closely. Contraindicated if eGFR <30 mL/min/1.73 m². |
| Hepatic Impairment | Not recommended in patients with severe hepatic impairment. In mild to moderate impairment, use with caution and monitor liver function. |
| Maximum Daily Dose | The maximum recommended daily dose is Metformin 2000 mg and Vildagliptin 100 mg. However, the exact dose depends on the individual patient's condition and should be determined by a doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of astroglip m 500mg/50mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Iodinated contrast media | Major | |
| Alcohol | Major | |
| Diuretics | Moderate | |
| Cationic drugs | Moderate | |
| Insulin | Moderate | |
| Sulfonylureas | Moderate | |
| ACE inhibitors | Minor |
🚨 Major Interactions
- Iodinated contrast media
- Alcohol
⚡ Moderate Interactions
- Diuretics (e.g., furosemide)
- Cationic drugs (e.g., amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamterene, trimethoprim, vancomycin)
- Insulin or sulfonylureas
🍷 Alcohol Interaction
Avoid excessive alcohol consumption. Alcohol increases the risk of lactic acidosis and hypoglycemia. If you drink alcohol, do so in moderation and only with your doctor's approval.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe renal impairment (eGFR
⚠️ Warnings & Precautions
["Lactic acidosis: Rare but serious. Discontinue and seek immediate medical help if suspected.","Pancreatitis: Has been reported with vildagliptin. Monitor for severe abdominal pain.","Hypoglycemia: Risk increases when used with insulin or sulfonylureas. Monitor blood glucose.","Renal impairment: Dose adjustment required based on eGFR. Contraindicated if eGFR
🤱 Lactation Safety
Metformin is excreted in human breast milk in small amounts. Vildagliptin is also excreted in rat milk. Consult your doctor before breastfeeding while taking this medicine.
💊 Overdose Management
Overdose may cause lactic acidosis, hypoglycemia, or pancreatitis. Seek immediate medical attention. Treatment is supportive and symptomatic. Hemodialysis may be considered for metformin removal in severe cases.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not skip doses or take extra doses. Inform your doctor about all other medicines, especially those for blood pressure, diuretics, and other diabetes drugs. Avoid excessive alcohol consumption as it increases the risk of lactic acidosis. Monitor your blood sugar regularly as advised. Maintain a healthy diet and exercise routine. If you are scheduled for surgery or imaging with contrast dye, inform your doctor as this medicine may need to be temporarily stopped. Do not use this medicine if you are pregnant or planning pregnancy without consulting your doctor.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of renal impairment and lactic acidosis. Renal function should be assessed before and during treatment. Dose adjustment may be necessary. Monitor for signs of hypoglycemia and other side effects.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. Insulin is generally preferred for managing diabetes during pregnancy. This medicine should be used during pregnancy only if clearly needed and prescribed by a doctor.
🏥 Post-Surgery Considerations
This medicine may need to be temporarily discontinued before surgery due to the risk of lactic acidosis and kidney problems. Inform your surgeon and anesthesiologist about all medicines you take. Resume only after your doctor approves.
🦷 Dental Procedures
Inform your dentist about this medicine before any dental procedure. No specific precautions are usually needed, but maintain good oral hygiene as diabetes can affect gum health.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise is encouraged as part of diabetes management. However, if you experience dizziness or weakness, avoid strenuous exercise and consult your doctor. Stay hydrated during exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness in some people. Avoid driving or operating heavy machinery if you feel dizzy. Otherwise, it should not significantly impact your daily activities. Maintain regular meal times for best effect.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience serious side effects like lactic acidosis, pancreatitis, or severe allergic reactions, stop immediately and seek medical help. Your doctor may adjust or change the medicine based on your condition.
📅 Long-Term Use Effects
Long-term use may lead to vitamin B12 deficiency due to metformin. Regular monitoring of B12 levels is advised. Kidney function should be monitored at least annually. Vildagliptin may rarely cause pancreatitis or liver enzyme elevation. Overall, the combination is well-tolerated and effective for long-term diabetes management.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet and exercise are cornerstone for managing type 2 diabetes and can reduce medication needs.
Evidence: Well-establishedAlternatives include Metformin with sulfonylureas, SGLT2 inhibitors, or GLP-1 receptor agonists.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, patients with diabetes should stay up to date with recommended vaccines, including influenza and pneumococcal vaccines, as they are at higher risk of infections.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing times gradually as advised by your doctor. Keep enough supply for the entire trip. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within days, but full effects on blood sugar may take 1-2 weeks. HbA1c reduction is typically seen after 3 months.
A: Your doctor will assess your kidney function. Dose adjustment is needed for mild to moderate impairment. It is contraindicated in severe kidney impairment.
A: Take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can cure diabetes.
Fact: This medicine helps manage blood sugar but does not cure diabetes. Lifestyle changes and medication are needed for long-term control. - Myth: This medicine causes weight gain.
Fact: Unlike some other diabetes medicines, this combination is weight-neutral or may cause slight weight loss. - Myth: You can stop taking this medicine once your sugar is normal.
Fact: Diabetes is a chronic condition. Stopping medication without doctor's advice can lead to serious complications.
🔄 Alternative Options
Generic Alternatives
- Metformin 500 mg + Vildagliptin 50 mg generic tablets
Brand Alternatives
- Zomelis Met 50/500
- Jalra M 50/500
- Galvus Met 50/500