astrobic 120 tablet - Etoricoxib (120mg) medicine

astrobic 120 tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Asterisk Laboratories India Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is astrobic 120 tablet used for?

Arixib 90 Tablet (Etoricoxib) is used to treat PAIN ANALGESICS. It contains Etoricoxib (120mg), which Selective inhibition of cyclooxygenase-2 (COX-2), reducing prostaglandin synthes. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Etoricoxib
  • Manufacturer: Asterisk Laboratories India Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š astrobic 120 tablet Uses & Benefits

Osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute gouty arthritis, dental pain, dysmenorrhea.

Off-label uses: Acute pain, migraine, cancer pain.

๐Ÿ“‹ Drug Information

Generic Name(s)Etoricoxib
Brand NameArixib 90 Tablet
ManufacturerAsterisk Laboratories India Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAID's -Selective COX-2 Inhibitors
Route of AdministrationOral.
StorageStore at room temperature (20-25ยฐC), protect from moisture and light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally; peak plasma concentration achieved in 1 hour.
DistributionExtensively distributed; crosses placenta and enters breast milk.
Protein Binding92% bound to plasma proteins.
MetabolismHepatic metabolism via CYP2C9, CYP3A4, and CYP2D6; forms inactive metabolites.
Half-LifeApproximately 22 hours.
ExcretionPrimarily excreted in urine as metabolites; less than 1% unchanged.
Bioavailability100% oral bioavailability.
Onset of ActionWithin 1 hour.
Peak Plasma Time1 hour.
Duration of ActionUp to 24 hours.

How It Works

Selective inhibition of cyclooxygenase-2 (COX-2), reducing prostaglandin synthesis.

Mechanism Steps

1Etoricoxib selectively binds to COX-2 enzyme.
2Inhibits conversion of arachidonic acid to prostaglandin H2.
3Reduces synthesis of prostaglandins (PGE2, PGI2) involved in inflammation and pain.

๐Ÿ’ก How to Take astrobic 120 tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of astrobic 120 tablet

โœ… Common Side Effects

  • Headache
  • Dizziness
  • Diarrhea
  • Dyspepsia
  • Nausea
  • Edema

๐Ÿšจ Serious Side Effects

  • GI bleeding
  • Peptic ulcer
  • Cardiovascular thrombotic events
  • Hypertension
  • Renal failure
  • Hepatotoxicity

โš ๏ธ Rare Side Effects

  • Stevens-Johnson syndrome
  • Anaphylaxis
  • Pancreatitis
  • Interstitial nephritis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Aspirin Major Increased risk of GI ulceration and bleeding
Methotrexate Major Increased methotrexate toxicity
Lithium Major Increased lithium levels and toxicity
ACE inhibitors Major Reduced antihypertensive effect
Diuretics Major Reduced diuretic effect and increased risk of renal impairment
Fluconazole Moderate Increased etoricoxib levels
Ketoconazole Moderate Increased etoricoxib levels
Corticosteroids Moderate Increased risk of GI ulceration
SSRIs Moderate Increased risk of bleeding
Antacids Minor Slight decrease in absorption
Cimetidine Minor No significant interaction

๐Ÿšจ Major Interactions

  • Warfarin
  • Aspirin
  • Methotrexate
  • Lithium
  • ACE inhibitors
  • Diuretics

โšก Moderate Interactions

  • CYP2C9 inhibitors (e.g., fluconazole)
  • CYP3A4 inhibitors (e.g., ketoconazole)
  • Corticosteroids
  • SSRIs

โ„น๏ธ Minor Interactions

  • Antacids
  • Cimetidine

๐Ÿฝ๏ธ Food Interactions

Food delays absorption but does not affect extent.

๐Ÿท Alcohol Interaction

Increased risk of GI bleeding.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity, active peptic ulcer, severe hepatic impairment, severe renal impairment, pregnancy (third trimester), history of asthma, urticaria, or allergic-type reactions after taking aspirin or NSAIDs.

๐Ÿ“Š Monitoring Parameters

Renal function, liver function, blood pressure, signs of GI bleeding, cardiovascular events.

๐Ÿคฑ Lactation Safety

Not recommended; excreted in breast milk.

๐Ÿ’Š Overdose Management

Symptomatic and supportive care; no specific antidote; consider gastric lavage if recent ingestion.

โฐ Missed Dose

Take as soon as remembered unless almost time for next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for astrobic 120 tablet

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Alternative brands with exact same active ingredient (Etoricoxib (120mg)):

Medical Note: Always consult your doctor before switching medications.

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