astnim 100mg tablet - Nimesulide (100mg) medicine

Astnim 100mg Tablet - Uses, Price, Side Effects

4.5 (16 reviews)
Nimesulide (100mg)
๐Ÿญ Astam Health Care Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 21, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 21, 2026

What is astnim 100mg tablet used for?

Astnim 100mg Tablet contains Nimesulide, a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain, inflammation, and fever. It works by blocking the production of prostaglandins, chemicals that cause pain and swelling. It is commonly prescribed for conditions like osteoarthritis, dental pain, and dysmenorrhea.

  • Generic Name: Nimesulide
  • Manufacturer: Astam Health Care Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š astnim 100mg tablet Uses & Benefits

Acute pain, dysmenorrhea, postoperative pain, musculoskeletal disorders, fever.

Off-label uses: Not commonly used off-label due to safety concerns.

๐Ÿ“‹ Drug Information

Generic Name(s)Nimesulide
Brand NameAulin 100mg Tablet
ManufacturerAstam Health Care Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAID's-Non-Selective COX 1&2 Inhibitors (Others)
Route of AdministrationOral
StorageStore at room temperature (15-30ยฐC), protect from moisture and light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration, with peak plasma concentrations achieved within 1-3 hours.
DistributionExtensively distributed to tissues; crosses the placenta and enters breast milk.
Protein Binding>97.5% bound to plasma proteins, primarily albumin.
MetabolismExtensively metabolized in the liver via CYP2C9 and other pathways; major metabolite is 4-hydroxynimesulide.
Half-LifeApproximately 1.8-4.7 hours.
ExcretionPrimarily renal (about 50-60% as metabolites, <1% unchanged); also biliary excretion.
BioavailabilityApproximately 100% after oral administration.
Onset of ActionWithin 15-30 minutes.
Peak Plasma Time1-3 hours.
Duration of Action6-8 hours.

How It Works

Selective inhibition of cyclooxygenase-2 (COX-2), reducing prostaglandin synthesis.

Mechanism Steps

1Inhibition of COX-2 enzyme
2Reduction of prostaglandin synthesis from arachidonic acid
3Decreased inflammation, pain, and fever

๐Ÿ’ก How to Take astnim 100mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of astnim 100mg tablet

โœ… Common Side Effects

  • Nausea
  • Dyspepsia
  • Diarrhea
  • Headache
  • Dizziness
  • Rash

๐Ÿšจ Serious Side Effects

  • Hepatotoxicity
  • Gastrointestinal bleeding
  • Stevens-Johnson syndrome
  • Acute renal failure
  • Anaphylaxis

โš ๏ธ Rare Side Effects

  • Thrombocytopenia
  • Agranulocytosis
  • Pancreatitis
  • Interstitial nephritis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Aspirin Moderate Increased risk of gastrointestinal ulceration
Lithium Moderate Increased lithium levels and toxicity
Methotrexate Major Increased methotrexate toxicity
Diuretics Moderate Reduced diuretic efficacy

๐Ÿšจ Major Interactions

  • Warfarin
  • Aspirin
  • Methotrexate
  • Lithium
  • Anticoagulants

โšก Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • Corticosteroids
  • Antiplatelet agents

โ„น๏ธ Minor Interactions

  • Antacids
  • Cimetidine

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption but does not significantly affect bioavailability.

๐Ÿท Alcohol Interaction

Increased risk of gastrointestinal bleeding and hepatotoxicity.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Moderate
Kidney
Moderate
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity to nimesulide or NSAIDs, active peptic ulcer, severe hepatic impairment, severe renal impairment, pregnancy (third trimester), lactation, children <12 years.

๐Ÿ“Š Monitoring Parameters

Liver function tests, renal function, blood pressure, signs of GI bleeding.

๐Ÿคฑ Lactation Safety

Contraindicated; excreted in breast milk.

๐Ÿ’Š Overdose Management

Symptomatic and supportive; no specific antidote; consider activated charcoal if recent ingestion.

โฐ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for astnim 100mg tablet

View All

Alternative brands with exact same active ingredient (Nimesulide (100mg)):

Medical Note: Always consult your doctor before switching medications.

โญ User Reviews

Trusted Reviewer Jul 10, 2026

Found this to be a helpful product. Good results.

Trusted Reviewer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Regular Customer Jul 10, 2026

Effective and reliable. Worked as expected.

Trusted Reviewer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Certified Buyer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

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