astharil-as syrup - Ambroxol (30mg/5ml) + Salbutamol (2mg/5ml) medicine

Astharil-AS Syrup - Uses, Price, Side Effects

4.4 (14 reviews)
๐Ÿญ Zoic Lifesciences ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 21, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 21, 2026

What is astharil-as syrup used for?

Astharil-AS Syrup is a combination medicine used to treat respiratory conditions like cough, asthma, and bronchitis. It contains Ambroxol, a mucolytic that thins mucus, and Salbutamol, a bronchodilator that relaxes airway muscles, making breathing easier. It is typically taken twice daily as prescribed.

  • Generic Name: Ambroxol + Salbutamol
  • Manufacturer: Zoic Lifesciences
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š astharil-as syrup Uses & Benefits

Productive cough, Bronchial asthma, Chronic bronchitis, COPD

๐Ÿ“‹ Drug Information

Generic Name(s)Ambroxol + Salbutamol
Brand NameAmbrodil-S Syrup
ManufacturerZoic Lifesciences
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassMucolytic + Beta-2 Adrenergic Agonist
Route of AdministrationOral
StorageStore below 25ยฐC, protect from light
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed from gastrointestinal tract
DistributionWidely distributed; crosses placenta and enters breast milk
Protein BindingAmbroxol: ~90%; Salbutamol: ~10%
MetabolismAmbroxol: Hepatic (glucuronidation); Salbutamol: Hepatic (sulfate conjugation)
Half-LifeAmbroxol: 7-12 hours; Salbutamol: 4-6 hours
ExcretionRenal (urine) and fecal
BioavailabilityAmbroxol: ~70%; Salbutamol: ~50%
Onset of ActionAmbroxol: 30 min; Salbutamol: 15-30 min
Peak Plasma TimeAmbroxol: 1-3 hours; Salbutamol: 2-4 hours
Duration of ActionAmbroxol: 6-12 hours; Salbutamol: 4-6 hours

How It Works

Ambroxol increases mucus clearance by stimulating surfactant production and reducing mucus viscosity; Salbutamol stimulates beta-2 adrenergic receptors, causing bronchodilation.

Mechanism Steps

1Ambroxol increases surfactant production in type II pneumocytes
2Ambroxol reduces mucus viscosity by breaking disulfide bonds in mucoproteins
3Salbutamol binds to beta-2 adrenergic receptors on bronchial smooth muscle

๐Ÿ’ก How to Take astharil-as syrup

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of astharil-as syrup

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Headache
  • Tremor
  • Palpitations

๐Ÿšจ Serious Side Effects

  • Hypokalemia
  • Cardiac arrhythmias
  • Bronchospasm (paradoxical)
  • Anaphylaxis

โš ๏ธ Rare Side Effects

  • Stevens-Johnson syndrome
  • Angioedema
  • Hepatotoxicity

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Beta-blockers Moderate May reduce bronchodilator effect
MAOIs Major Increased risk of hypertensive crisis
Diuretics Moderate Hypokalemia risk

๐Ÿšจ Major Interactions

  • Beta-blockers (e.g., propranolol)
  • MAOIs
  • Tricyclic antidepressants

โšก Moderate Interactions

  • Diuretics
  • Corticosteroids
  • Xanthine derivatives

โ„น๏ธ Minor Interactions

  • Anticholinergics
  • Other sympathomimetics

๐Ÿฝ๏ธ Food Interactions

No significant interactions

๐Ÿท Alcohol Interaction

Avoid alcohol; may increase sedation or hepatotoxicity risk

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Moderate
Pregnancy
Category C

๐Ÿšซ Contraindications

Hypersensitivity to components, Cardiac arrhythmias, Hypertrophic obstructive cardiomyopathy, Severe hypertension

๐Ÿ“Š Monitoring Parameters

Respiratory rate, Heart rate, Blood pressure, Sputum characteristics, Serum electrolytes

๐Ÿคฑ Lactation Safety

Use with caution; both components excreted in breast milk

๐Ÿ’Š Overdose Management

Gastric lavage, activated charcoal, symptomatic treatment; monitor cardiac function

โฐ Missed Dose

Take as soon as remembered; skip if near next dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

๐Ÿ”— View Profile

โญ User Reviews

Certified Buyer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Verified User Jul 10, 2026

Found this to be a helpful product. Good results.

Regular Customer Jul 10, 2026

Found this to be a helpful product. Good results.

Happy Patient Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Regular Customer Jul 10, 2026

Found this to be a helpful product. Good results.

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