asthagrip dm tablet - Acebrophylline (200mg) + Desloratadine (5mg) medicine

asthagrip dm tablet

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🏭 Druto Laboratories 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

What is asthagrip dm tablet used for?

This medicine contains Acebrophylline (200mg) + Desloratadine (5mg) and is used to treat RESPIRATORY. Acebrophylline: Bronchodilator and mucolytic; Desloratadine: H1-receptor antagonist.. Always consult your doctor before use.

  • Generic Name: Acebrophylline + Desloratadine
  • Manufacturer: Druto Laboratories
  • Form: Allopathy
  • Pregnancy Category: Category C
  • Prescription Required: Yes
💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 asthagrip dm tablet Uses & Benefits

Allergic rhinitis, asthma, COPD.

Off-label uses: Urticaria, chronic cough.

📋 Drug Information

Generic Name(s)Acebrophylline + Desloratadine
Brand NameAbmac Tablet
ManufacturerDruto Laboratories
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassRespiratory
Route of AdministrationOral
StorageStore at room temperature (20-25°C), protect from moisture.
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAcebrophylline: Well absorbed orally; Desloratadine: Well absorbed orally.
DistributionAcebrophylline: Distributed widely; Desloratadine: Distributed widely, crosses blood-brain barrier minimally.
Protein BindingAcebrophylline: ~50%; Desloratadine: 82-87%.
MetabolismAcebrophylline: Hepatic via CYP450; Desloratadine: Hepatic via CYP2C8 and CYP3A4.
Half-LifeAcebrophylline: ~8 hours; Desloratadine: ~27 hours.
ExcretionAcebrophylline: Renal (70% unchanged); Desloratadine: Renal and fecal.
BioavailabilityAcebrophylline: ~100%; Desloratadine: ~40%.
Onset of ActionAcebrophylline: 1-2 hours; Desloratadine: 1-3 hours.
Peak Plasma TimeAcebrophylline: 2-4 hours; Desloratadine: 3-4 hours.
Duration of ActionAcebrophylline: 12 hours; Desloratadine: 24 hours.

How It Works

Acebrophylline: Bronchodilator and mucolytic; Desloratadine: H1-receptor antagonist.

Mechanism Steps

1Acebrophylline inhibits phosphodiesterase, increasing cAMP levels.
2Acebrophylline blocks adenosine receptors, reducing bronchoconstriction.
3Acebrophylline reduces mucus viscosity by breaking disulfide bonds.
4Desloratadine selectively blocks peripheral H1 receptors.
5Desloratadine inhibits histamine release from mast cells.
6Combined effect: bronchodilation and reduced allergic response.

💡 How to Take asthagrip dm tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of asthagrip dm tablet

✅ Common Side Effects

Headache
Dry mouth
Fatigue
Nausea

🚨 Serious Side Effects

Hypersensitivity reactions
Hepatotoxicity
Cardiac arrhythmias

⚠️ Rare Side Effects

Seizures
Thrombocytopenia
Stevens-Johnson syndrome

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ketoconazole Moderate Increased desloratadine levels
Erythromycin Moderate Increased desloratadine levels
Fluoxetine Moderate Increased desloratadine levels
Cimetidine Minor Increased acebrophylline levels
Alcohol Minor Increased sedation

🚨 Major Interactions

  • CYP3A4 inhibitors
  • CYP2C8 inhibitors
  • Monoamine oxidase inhibitors

⚡ Moderate Interactions

  • Ketoconazole
  • Erythromycin
  • Fluoxetine

🍷 Alcohol Interaction

May increase sedation risk.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to any component, severe hepatic impairment.

🤱 Lactation Safety

Caution advised; desloratadine excreted in breast milk.

💊 Overdose Management

Symptomatic and supportive treatment; no specific antidote.

⏰ Missed Dose

Take as soon as remembered; skip if almost time for next dose.

🔄 Substitutes for asthagrip dm tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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