asponet 50 injection - Caspofungin (50mg) medicine

Asponet 50 Injection (Caspofungin 50mg) - Uses, Price, Side Effects

4.7 (15 reviews)
Caspofungin (50mg)
๐Ÿญ Tyykem Private Limited ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 23, 2026
โš ๏ธ Hepatotoxicity Risk ๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 23, 2026

What is asponet 50 injection used for?

Asponet 50 Injection contains Caspofungin 50mg, an echinocandin antifungal. It is used to treat invasive candidiasis and aspergillosis in patients who are intolerant or refractory to other therapies. It works by inhibiting fungal cell wall synthesis, leading to cell death.

  • Generic Name: Caspofungin
  • Manufacturer: Tyykem Private Limited
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š asponet 50 injection Uses & Benefits

Invasive candidiasis, esophageal candidiasis, invasive aspergillosis (refractory or intolerant to other therapies), empirical therapy for febrile neutropenia.

Off-label uses: Candidemia in neonates, Endocarditis due to Candida, Osteomyelitis due to Candida

๐Ÿ“‹ Drug Information

Generic Name(s)Caspofungin
Brand NameAsponet 50 Injection
ManufacturerTyykem Private Limited
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOTHERS
Action ClassFungal cell wall synthesis inhibitor (Echiocandins)
Route of AdministrationIntravenous infusion.
StorageStore at 2-8ยฐC. Do not freeze. Protect from light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionIntravenous administration results in complete bioavailability.
DistributionExtensively distributed into tissues, including liver, lungs, and spleen.
Protein BindingApproximately 97% bound to albumin.
MetabolismSlowly metabolized by hydrolysis and N-acetylation, with some spontaneous degradation.
Half-Life9-11 hours (beta phase); terminal half-life 40-50 hours.
ExcretionPrimarily in feces (35%) and urine (41%) as metabolites and unchanged drug.
Bioavailability100% (intravenous).
Onset of ActionRapid; antifungal effect within hours.
Peak Plasma TimeEnd of infusion.
Duration of ActionOnce daily dosing maintains therapeutic levels.

How It Works

Inhibits synthesis of beta-(1,3)-D-glucan, an essential component of fungal cell walls.

Mechanism Steps

1Caspofungin binds to beta-(1,3)-D-glucan synthase.
2Inhibits the synthesis of beta-(1,3)-D-glucan, a key component of fungal cell walls.
3Disruption of cell wall integrity leads to osmotic instability and cell death.

๐Ÿ’ก How to Take asponet 50 injection

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of asponet 50 injection

โœ… Common Side Effects

  • Fever
  • Nausea
  • Vomiting
  • Diarrhea
  • Headache
  • Phlebitis
  • Elevated liver enzymes

๐Ÿšจ Serious Side Effects

  • Anaphylaxis
  • Hepatotoxicity
  • Renal impairment
  • Hemolytic anemia
  • Stevens-Johnson syndrome

โš ๏ธ Rare Side Effects

  • Pancreatitis
  • Seizures
  • Pulmonary edema
  • Thrombotic thrombocytopenic purpura

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Cyclosporine Moderate Increased risk of hepatotoxicity
Tacrolimus Moderate Increased risk of nephrotoxicity
Rifampin Major Reduced caspofungin efficacy

๐Ÿšจ Major Interactions

  • Cyclosporine
  • Tacrolimus
  • Rifampin
  • Efavirenz
  • Nevirapine
  • Phenytoin
  • Dexamethasone
  • Carbamazepine

โšก Moderate Interactions

  • Sirolimus
  • Nifedipine
  • Midazolam

โ„น๏ธ Minor Interactions

  • Itraconazole
  • Posaconazole
  • Voriconazole

๐Ÿฝ๏ธ Food Interactions

None (IV administration).

๐Ÿท Alcohol Interaction

No known interaction.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Moderate
Kidney
Low
Heart
Low
Pregnancy
Category C

๐Ÿšซ Contraindications

Hypersensitivity to caspofungin or any component.

๐Ÿ“Š Monitoring Parameters

Liver function tests, renal function, complete blood count, signs of infusion reactions.

๐Ÿคฑ Lactation Safety

Unknown; caution advised.

๐Ÿ’Š Overdose Management

Supportive care; no specific antidote. Hemodialysis not effective.

โฐ Missed Dose

Administer as soon as remembered; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for asponet 50 injection

View All

Alternative brands with exact same active ingredient (Caspofungin (50mg)):

Medical Note: Always consult your doctor before switching medications.

โญ User Reviews

Trusted Reviewer Jul 10, 2026

Found this to be a helpful product. Good results.

Trusted Reviewer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Verified User Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Happy Patient Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Happy Patient Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

๐Ÿ˜Š Was this information helpful?

Browse Medicines A-Z

Search our extensive medical database alphabetically.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory