Asomex-OH Tablet - Uses, Price, Side Effects, Dosage
What is asomex-oh tablet used for?
Asomex-OH Tablet is a combination of Olmesartan Medoxomil (20mg) and Amlodipine (2.5mg) used to treat high blood pressure. Olmesartan relaxes blood vessels by blocking angiotensin II, while Amlodipine is a calcium channel blocker that widens arteries, together lowering blood pressure effectively.
- Generic Name: Olmesartan Medoxomil + Amlodipine
- Manufacturer: Emcure Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ asomex-oh tablet Uses & Benefits
Off-label uses: Chronic kidney disease, diabetic nephropathy, heart failure (with caution).
๐ Drug Information
| Generic Name(s) | Olmesartan Medoxomil + Amlodipine |
| Brand Name | Asomex-OH Tablet |
| Manufacturer | Emcure Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Angiotensin II Receptor Blocker + Calcium Channel Blocker |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Olmesartan blocks angiotensin II AT1 receptors; Amlodipine inhibits calcium influx in vascular smooth muscle and cardiac muscle.
Mechanism Steps
๐ก How to Take asomex-oh tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of asomex-oh tablet
โ Common Side Effects
- Edema
- Dizziness
- Headache
- Fatigue
- Nausea
๐จ Serious Side Effects
- Hypotension
- Hyperkalemia
- Renal impairment
- Angioedema
- Hepatotoxicity
โ ๏ธ Rare Side Effects
- Stevens-Johnson syndrome
- Interstitial nephritis
- Pancreatitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Lithium | Moderate | Increased lithium toxicity risk |
| NSAIDs | Moderate | Reduced antihypertensive effect |
| Potassium supplements | Major | Hyperkalemia risk |
๐จ Major Interactions
- Lithium
- NSAIDs
- Potassium-sparing diuretics
- CYP3A4 inhibitors (e.g., ketoconazole)
- CYP3A4 inducers (e.g., rifampin)
โก Moderate Interactions
- Antidiabetic agents
- Digoxin
- Simvastatin
- Cyclosporine
โน๏ธ Minor Interactions
- Antacids
- Grapefruit juice
๐ฝ๏ธ Food Interactions
Avoid grapefruit juice (may increase amlodipine levels).
๐ท Alcohol Interaction
May potentiate hypotensive effects.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, pregnancy, bilateral renal artery stenosis, severe hypotension, cardiogenic shock.
๐ Monitoring Parameters
Blood pressure, serum potassium, renal function, liver function.
๐คฑ Lactation Safety
Not recommended; excreted in breast milk.
๐ Overdose Management
Symptomatic and supportive; hypotension may require IV fluids and vasopressors.
โฐ Missed Dose
Take as soon as remembered; skip if almost time for next dose.