Artebest Injection (alpha-beta Arteether 75 Mg/ml): Complete Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of the face, lips, or throat
- Severe chest pain or palpitations
- Fainting or loss of consciousness
- Yellowing of the eyes or skin
- Dark urine or decreased urine output
- Severe abdominal pain or persistent vomiting
- Unusual bleeding or bruising
- High fever that does not come down after treatment
If experiencing severe symptoms, call emergency services immediately.
What is artebest injection used for?
This medicine is an injectable antimalarial containing Alpha-Beta Arteether 75 mg/ml. It is given by intramuscular injection to treat severe malaria caused by Plasmodium falciparum. It works by killing the malaria parasite in the blood. It must be given by a healthcare professional and is not for self-administration.
- Generic Name: Alpha-Beta Arteether
- Manufacturer: Balsons Pharmaceutical
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 artebest injection के बारे में (Hindi Summary)
उपयोग: यह दवा अल्फा-बीटा आर्टीथर का इंजेक्शन है, जिसका उपयोग गंभीर मलेरिया (मलेरिया के गंभीर रूप) के इलाज के लिए किया जाता है। यह मलेरिया परजीवी को खून में मारती है और बुखार तथा अन्य लक्षणों को कम करने में मदद करती है। यह इंजेक्शन डॉक्टर या नर्स द्वारा मांसपेशी में लगाया जाता है। इसे घर पर स्वयं नहीं लगाया जाना चाहिए। यह दवा उन रोगियों के लिए है जिन्हें गंभीर मलेरिया है और जो मुंह से दवा नहीं ले सकते।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन वाली जगह पर दर्द, सूजन, हल्का बुखार, सिरदर्द, चक्कर आना, जी मिचलाना और पेट में असहजता शामिल हैं। ये आमतौर पर हल्के होते हैं और अपने आप ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, सांस लेने में कठिनाई, दिल की धड़कन में बदलाव, पीलिया, या बहुत कम शुगर जैसी समस्याएं हो सकती हैं। अगर कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल डॉक्टर या प्रशिक्षित स्वास्थ्यकर्मी द्वारा ही लगाई जानी चाहिए। इसे घर पर स्वयं न लगाएं। अपने डॉक्टर को अपनी सभी दवाओं, हृदय रोग, लीवर या किडनी की बीमारी, और एलर्जी के बारे में बताएं। इलाज के दौरान शराब न पिएं। अगर आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें। इलाज पूरा करें, बीच में न छोड़ें, भले ही आप बेहतर महसूस करें। नियमित जांच के लिए डॉक्टर के पास जाएं।
💊 artebest injection Uses & Benefits
[{"condition":"Severe falciparum malaria","description":"This medicine is used for the initial treatment of severe or complicated malaria caused by Plasmodium falciparum when oral therapy is not suitable.","evidence":"Well-established"},{"condition":"Cerebral malaria","description":"It may be used in patients with cerebral malaria as part of a hospital-based treatment plan, often followed by oral antimalarial therapy.","evidence":"Well-established"},{"condition":"Multidrug-resistant malaria","description":"It can be considered in areas where malaria parasites are resistant to older antimalarial medicines, under specialist guidance.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Not established from the available information.","description":"No well-established off-label uses are documented for this medicine.","evidence":"Limited"}]
Primary treatment for: Severe falciparum malaria
Also treats: Cerebral malaria, Multidrug-resistant malaria
📋 Drug Information
| Generic Name(s) | Alpha-Beta Arteether |
| Brand Name | Alpha Beta-Click Injection |
| Manufacturer | Balsons Pharmaceutical |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI MALARIALS |
| Action Class | Antimalarial- Artemisinin and derivatives |
| Route of Administration | Intramuscular injection. This medicine is injected into a large muscle, usually the buttock or thigh, by a trained healthcare professional |
| Storage | Store in a cool, dry place, protected from light. Do not freeze. Keep out of reach of children. Follow the storage instructions on the pack. |
| Shelf Life | Refer to the expiry date printed on the pack. Do not use after the expiry date. |
| WHO Guideline | The World Health Organization recommends artemisinin-based combination therapies for the treatment of uncomplicated malaria and intravenous or intramuscular artesunate for severe malaria. Alpha-Beta Arteether is an artemisinin derivative used in some countries for severe malaria, but it is not the first-line choice in all guidelines. Always follow local guidelines. |
| ICMR Guideline | The Indian Council of Medical Research guidelines for malaria treatment in India recommend artemisinin-based combination therapy for uncomplicated falciparum malaria and parenteral artesunate or artemether for severe malaria. Alpha-Beta Arteether may be used in some settings as an alternative, based on availability and clinician judgment. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Alpha-Beta Arteether is a semisynthetic artemisinin derivative. Inside the malaria parasite, it is activated by iron-containing heme molecules to form reactive oxygen species and free radicals. These reactive molecules damage parasite proteins, membranes, and organelles, leading to rapid destruction of the parasite. This medicine is most active against the blood-stage forms of Plasmodium falciparum, which are responsible for the symptoms and complications of malaria.
Mechanism Steps
💡 How to Take artebest injection
Strength: Injection: Alpha-Beta Arteether 75 mg/ml. The pack may contain 75 mg in 1 ml or 150 mg in 2 ml ampoules or vials.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is determined by a qualified clinician based on the severity of malaria, body weight, and kidney and liver function. A common regimen is 150 mg (2 ml of 75 mg/ml) given by intramuscular injection once daily for 3 days, but this may vary. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-administer. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine may be used in children with severe malaria under specialist supervision, but the dose must be calculated by a qualified clinician based on weight and clinical condition. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially heart rhythm changes and dizziness. The dose should be individualized by a clinician, and monitoring for side effects is recommended. |
| Renal Impairment | There is limited information on the use of this medicine in patients with kidney disease. The dose may need to be adjusted based on clinical judgment and kidney function tests. Consult your doctor. |
| Hepatic Impairment | There is limited information on the use of this medicine in patients with liver disease. The dose may need to be adjusted based on clinical judgment and liver function tests. Consult your doctor. |
| Maximum Daily Dose | The maximum daily dose is not established from the available information. The dose must be determined by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of artebest injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Amiodarone | Major | |
| Ketoconazole | Major | |
| Rifampicin | Major | |
| Warfarin | Moderate | |
| Mefloquine | Moderate | |
| Paracetamol | Minor |
🚨 Major Interactions
- Drugs that prolong QT interval (e.g., amiodarone, sotalol, certain antipsychotics)
- Strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
- Strong CYP3A4 inducers (e.g., rifampicin, carbamazepine)
⚡ Moderate Interactions
- Anticoagulants (e.g., warfarin)
- Other antimalarials (e.g., mefloquine, lumefantrine)
🍷 Alcohol Interaction
Avoid alcohol while receiving this medicine. Alcohol can increase the risk of liver problems and dehydration, and it may worsen side effects such as dizziness and nausea.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to Alpha-Beta Arteether or other artemisinin derivatives","Use for uncomplicated malaria when oral therapy is appropriate","Self-administration outside a healthcare setting","Concurrent use with certain drugs that strongly prolong QT interval, unless under specialist supervision"]
⚠️ Warnings & Precautions
["This medicine must be given only by a healthcare professional.","Do not use this medicine for prevention of malaria.","Inform your doctor if you have heart, liver, or kidney disease.","Avoid alcohol during treatment.","Tell your doctor about all other medicines you are taking.","Do not stop treatment early even if you feel better.","Follow up with your doctor to confirm that the malaria parasite has cleared from your blood."]
🤱 Lactation Safety
It is not known whether this medicine passes into breast milk. Because it is given as a short course injection for severe malaria, breastfeeding may be continued if the mother is able to do so, but you should discuss this with your doctor. If you are expressing milk, ask your doctor whether it is safe to feed it to your baby.
💊 Overdose Management
Overdose with this medicine is unlikely because it is given by a healthcare professional. If an overdose is suspected, seek immediate medical attention. Treatment is supportive and may include monitoring of heart rhythm, blood pressure, and liver and kidney function.
⏰ Missed Dose
This medicine is given as a scheduled injection in a hospital or clinic. If you miss an appointment for your injection, contact your healthcare provider as soon as possible to reschedule. Do not try to self-administer a missed dose.
Additional Safety Advice
This medicine must be given only by a trained healthcare professional as an intramuscular injection. Do not attempt to self-administer this medicine at home. Inform your doctor about all other medicines you are taking, especially drugs that affect heart rhythm, because this medicine can interact with them. Tell your doctor if you have heart problems, liver disease, kidney disease, or a history of allergic reactions to antimalarial medicines. Avoid alcohol during treatment because it can worsen liver stress and dehydration. If you are pregnant or breastfeeding, your doctor will decide whether the benefits outweigh the risks. Keep all follow-up appointments so that your response to treatment and any side effects can be monitored. Do not stop treatment early even if you feel better, because incomplete treatment can lead to relapse and drug resistance.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more prone to side effects such as dizziness, heart rhythm changes, and low blood sugar. They should be monitored closely during treatment. The dose may need to be adjusted based on kidney and liver function.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, discuss with your doctor before receiving this medicine. Artemisinin derivatives are generally avoided in the first trimester unless the situation is life-threatening. If you become pregnant during treatment, inform your doctor immediately.
🏥 Post-Surgery Considerations
If you have recently had surgery, inform your surgeon and anesthesiologist that you are receiving this medicine. It may affect heart rhythm and blood sugar, which are important during surgery and recovery.
🦷 Dental Procedures
Inform your dentist that you are receiving this medicine before any dental procedure. It may cause dizziness or heart rhythm changes, and your dentist may need to take precautions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise during the acute phase of severe malaria and while you are recovering. Rest is important. Once you feel better, gradually return to your normal activities. Consult your doctor before starting any intense exercise routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
Severe malaria requires hospitalization and treatment with injections, so you will need to take time off work or school. After treatment, you may feel weak for a few days. Avoid driving or operating heavy machinery if you feel dizzy. Gradually return to your normal routine as you recover.
🛑 When to Stop This Medicine
This medicine is given as a short course by a healthcare professional. Do not stop the course early even if you feel better. If you experience a serious side effect such as difficulty breathing, severe palpitations, or yellowing of the eyes, stop the injection and seek immediate medical attention. Your doctor will decide whether to continue or change the treatment.
📅 Long-Term Use Effects
This medicine is usually given as a short course of injections for severe malaria. Long-term effects are not well established because it is not intended for prolonged use. However, repeated or prolonged use of artemisinin derivatives may raise concerns about heart rhythm changes and liver enzyme elevation. Follow-up blood tests are recommended to confirm that the malaria parasite has cleared. If you experience any unusual symptoms after treatment, report them to your doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Another artemisinin derivative that is often the first choice for severe malaria in many guidelines.
Evidence: Well-establishedAnother artemisinin derivative used for severe malaria.
Evidence: Well-establishedAn older antimalarial that may be used if artemisinin derivatives are not available.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are due for a vaccine, inform your doctor that you are receiving treatment for severe malaria. Vaccination may be postponed until you have recovered.
📦 Storage Guide
✅ DO
Store in a cool, dry place, protected from light.
❌ DON'T
Do not freeze the injection.
✅ DO
Keep in the original container until use.
❌ DON'T
Do not use if the solution is discolored or contains particles.
✅ DO
Keep out of reach of children.
❌ DON'T
Do not store in a bathroom cabinet.
✈️ Traveling with This Medicine
If you are traveling and need this medicine, it must be given by a healthcare professional. Carry a copy of your prescription and medical records. This medicine should be stored in its original packaging, protected from light and heat. Do not freeze. If you are traveling to a malaria-endemic area, take precautions to prevent mosquito bites. If you develop fever during or after travel, seek medical attention immediately and inform the doctor about your travel history.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts reducing the malaria parasite in the blood within hours. Fever and other symptoms usually improve within 24 to 48 hours, but you must complete the full course as prescribed.
A: This medicine may be used in pregnancy if you have severe malaria and the doctor decides the benefits outweigh the risks. It is usually avoided in the first trimester unless the situation is life-threatening. Always consult your doctor.
A: Contact your healthcare provider as soon as possible to reschedule. Do not try to self-administer the injection.
A: Avoid alcohol and grapefruit juice during treatment. Eat light, nutritious meals to help your recovery.
A: This medicine can cause dizziness. Avoid driving or operating machinery until you feel completely normal.
🤔 Common Patient Concerns
🔄 Substitutes for artebest injection
View AllAlternative brands with exact same active ingredient:
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falcimether injectionIntas Pharmaceuticals Ltd ₹12.60 84.2% CHEAPER
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mosther 75mg injectionLinnet Life Sciences ₹23.44 70.6% CHEAPER
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Stanther 150mg InjectionStandard Remedies Pvt Ltd ₹24.68 69% CHEAPER
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laristar 150mg injectionBaltic Pharmaceuticals ₹42.19 47.1% CHEAPER
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depther 75mg/ml injectionDaksh Pharma Pvt Ltd ₹45.00 43.5% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken at home like a tablet.
Fact: This medicine is an injection and must be given by a healthcare professional in a clinic or hospital. - Myth: This medicine can prevent malaria.
Fact: This medicine is used to treat severe malaria, not to prevent it. - Myth: You can stop treatment once you feel better.
Fact: You must complete the full course as prescribed to prevent relapse and resistance.
🔄 Alternative Options
Generic Alternatives
- Alpha-Beta Arteether injection
Brand Alternatives
- Artebest Injection