arridruff 2% shampoo - Ketoconazole (2% w/v) medicine

Arridruff 2% Shampoo - Uses, Price, Side Effects

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๐Ÿญ Smayan Healthcare Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
โš ๏ธ Hepatotoxicity Risk ๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is arridruff 2% shampoo used for?

Arridruff 2% Shampoo contains Ketoconazole, an antifungal agent used to treat dandruff and seborrheic dermatitis. It works by inhibiting the growth of fungi that cause these conditions. Apply to wet hair, lather, leave for 5 minutes, then rinse. Use twice weekly for best results.

  • Generic Name: Ketoconazole
  • Manufacturer: Smayan Healthcare Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š arridruff 2% shampoo Uses & Benefits

Dandruff, seborrheic dermatitis, tinea versicolor, and fungal infections of the scalp.

Off-label uses: Tinea capitis, Candidal intertrigo, Pityriasis versicolor

๐Ÿ“‹ Drug Information

Generic Name(s)Ketoconazole
Brand NameAzolbest-KT Shampoo
ManufacturerSmayan Healthcare Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL OTOLOGICALS
Action ClassFungal ergosterol synthesis inhibitor
Route of AdministrationTopical (shampoo).
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionMinimal systemic absorption when applied topically; approximately 0.1% of dose absorbed through scalp skin.
DistributionDistributed mainly in skin and hair; negligible systemic distribution due to low absorption.
Protein Binding99% bound to plasma proteins (mainly albumin) if absorbed systemically.
MetabolismHepatic via CYP3A4; extensive first-pass metabolism if absorbed.
Half-Life2-4 hours (systemic); not applicable for topical use.
ExcretionPrimarily feces (biliary) and urine (renal) for absorbed fraction.
BioavailabilityNegligible (<0.5%) after topical application.
Onset of ActionWithin 1-2 weeks of regular use for antifungal effect.
Peak Plasma TimeNot applicable due to minimal systemic absorption.
Duration of ActionSustained antifungal effect with regular use; remains on hair and scalp for days.

How It Works

Inhibits fungal CYP450 14ฮฑ-demethylase, blocking ergosterol synthesis and disrupting fungal cell membrane integrity.

Mechanism Steps

1Ketoconazole enters fungal cell via diffusion.
2Binds to fungal CYP450 14ฮฑ-demethylase (ERG11).
3Inhibits conversion of lanosterol to ergosterol.

๐Ÿ’ก How to Take arridruff 2% shampoo

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of arridruff 2% shampoo

โœ… Common Side Effects

  • Scalp irritation
  • Dryness
  • Oiliness
  • Hair discoloration
  • Pruritus

๐Ÿšจ Serious Side Effects

  • Severe allergic reaction (rash, urticaria, angioedema)
  • Hepatotoxicity (rare)

โš ๏ธ Rare Side Effects

  • Contact dermatitis
  • Hair loss
  • Alopecia

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Corticosteroids (topical) Moderate May mask skin infections or reduce efficacy
Antifungals (oral) Minor Additive antifungal effect

๐Ÿšจ Major Interactions

  • Warfarin
  • CYP3A4 substrates (e.g., midazolam, triazolam)
  • Cisapride
  • Terfenadine
  • Astemizole

โšก Moderate Interactions

  • Oral hypoglycemics
  • Anticoagulants
  • Phenytoin
  • Rifampin
  • Isoniazid

โ„น๏ธ Minor Interactions

  • Antacids
  • H2 blockers
  • Proton pump inhibitors

๐Ÿฝ๏ธ Food Interactions

No significant food interactions for topical use.

๐Ÿท Alcohol Interaction

No known interaction with topical use.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity to ketoconazole or any component; avoid on broken or inflamed skin.

๐Ÿ“Š Monitoring Parameters

Clinical improvement of scalp condition; liver function tests if prolonged use or signs of hepatotoxicity.

๐Ÿคฑ Lactation Safety

Excretion in breast milk unknown; use with caution on small areas.

๐Ÿ’Š Overdose Management

Unlikely with topical use; accidental ingestion may cause nausea, vomiting; symptomatic treatment.

โฐ Missed Dose

Apply as soon as remembered; skip if almost time for next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for arridruff 2% shampoo

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Alternative brands with exact same active ingredient (Ketoconazole (2% w/v)):

Medical Note: Always consult your doctor before switching medications.

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