arixtra 7.5mg injection - Fondaparinux (7.5mg) medicine

arixtra 7.5mg injection - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Glaxo SmithKline Pharmaceuticals Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is arixtra 7.5mg injection used for?

Arixtra (Fondaparinux) is used to treat CARDIAC. It contains Fondaparinux (7.5mg), which Selective inhibition of factor Xa via antithrombin III. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Fondaparinux
  • Manufacturer: Glaxo SmithKline Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: B
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š arixtra 7.5mg injection Uses & Benefits

Prophylaxis of deep vein thrombosis, treatment of acute DVT and PE, anticoagulation in ACS

Off-label uses: Anticoagulation during PCI, VTE prophylaxis in medical patients

๐Ÿ“‹ Drug Information

Generic Name(s)Fondaparinux
Brand NameArixtra
ManufacturerGlaxo SmithKline Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassSelective inhibitor of activated Factor X
Route of AdministrationSubcutaneous injection
StorageStore at 25ยฐC (77ยฐF); excursions permitted to 15-30ยฐC
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapid and complete after subcutaneous injection
DistributionDistributes mainly in blood, volume of distribution 7-11 L
Protein BindingHighly bound to antithrombin III (>94%)
MetabolismMinimal metabolism; not metabolized by cytochrome P450
Half-Life17-21 hours
ExcretionRenal excretion as unchanged drug
Bioavailability100% after subcutaneous injection
Onset of ActionRapid (within 1-2 hours)
Peak Plasma Time2-3 hours
Duration of Action24 hours

How It Works

Selective inhibition of factor Xa via antithrombin III

Mechanism Steps

1Binds to antithrombin III
2Induces conformational change in antithrombin III
3Enhances antithrombin III-mediated inhibition of factor Xa

๐Ÿ’ก How to Take arixtra 7.5mg injection

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of arixtra 7.5mg injection

โœ… Common Side Effects

  • Bleeding
  • Anemia
  • Injection site reaction
  • Fever
  • Nausea

๐Ÿšจ Serious Side Effects

  • Major hemorrhage
  • Spinal hematoma with neuraxial anesthesia
  • Thrombocytopenia

โš ๏ธ Rare Side Effects

  • Allergic reaction
  • Eosinophilia
  • Elevated liver enzymes

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Aspirin Moderate Increased bleeding risk
Clopidogrel Moderate Increased bleeding risk
NSAIDs Moderate Increased bleeding risk

๐Ÿšจ Major Interactions

  • Warfarin
  • Heparin
  • Direct thrombin inhibitors
  • Other anticoagulants

โšก Moderate Interactions

  • Aspirin
  • NSAIDs
  • Clopidogrel
  • SSRIs

โ„น๏ธ Minor Interactions

  • Herbal supplements with anticoagulant effects

๐Ÿฝ๏ธ Food Interactions

No significant food interactions

๐Ÿท Alcohol Interaction

May increase bleeding risk

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Severe renal impairment (CrCl <30 mL/min), active bleeding, hypersensitivity, body weight <50 kg (for prophylaxis), bacterial endocarditis

๐Ÿ“Š Monitoring Parameters

Renal function, CBC, signs of bleeding

๐Ÿคฑ Lactation Safety

Not recommended; excreted in breast milk

๐Ÿ’Š Overdose Management

Protamine sulfate is ineffective; consider recombinant factor VIIa

โฐ Missed Dose

Take as soon as remembered if within 12 hours; otherwise skip

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for arixtra 7.5mg injection

View All

Alternative brands with exact same active ingredient (Fondaparinux (7.5mg)):

Medical Note: Always consult your doctor before switching medications.

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