zeexib 90 tablet - Etoricoxib (90mg) medicine

Etoshine 90 Tablet (Etoricoxib 90mg): Complete Medicine Guide

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🏭 Zeelab Pharmacy Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is zeexib 90 tablet used for?

This medicine is a selective COX-2 inhibitor used to treat pain and inflammation in conditions like osteoarthritis, rheumatoid arthritis, and gout. It is taken orally once daily and should be used under medical supervision.

  • Generic Name: Etoricoxib (90mg)
  • Manufacturer: Zeelab Pharmacy Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 zeexib 90 tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एटोरिकॉक्सिब 90 मिलीग्राम टैबलेट है, जिसका उपयोग गठिया (ऑस्टियोआर्थराइटिस, रूमेटॉइड आर्थराइटिस), एंकिलोज़िंग स्पॉन्डिलाइटिस और गाउट के दौरे में दर्द और सूजन को कम करने के लिए किया जाता है। यह एक प्रिस्क्रिप्शन दवा है और इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, चक्कर आना, पेट खराब होना, मतली और रक्तचाप में वृद्धि शामिल हैं। गंभीर दुष्प्रभावों में पेट में रक्तस्राव, दिल का दौरा, स्ट्रोक और गुर्दे की समस्याएं हो सकती हैं। यदि आपको काला मल, खून की उल्टी, सीने में दर्द या सांस लेने में कठिनाई हो, तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे भोजन के साथ लें ताकि पेट में जलन न हो। इस दवा के साथ शराब न लें। यदि आपको हृदय रोग, उच्च रक्तचाप, गुर्दे या यकृत की समस्या है, तो डॉक्टर को बताएं। गर्भावस्था या स्तनपान के दौरान इस दवा का उपयोग करने से पहले डॉक्टर से सलाह लें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 zeexib 90 tablet Uses & Benefits

[{"condition":"Osteoarthritis","description":"Relieves pain and improves joint mobility in knee, hip, and hand osteoarthritis.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Reduces joint pain, inflammation" class="semantic-link" title="Medicines for swelling">swelling, and stiffness in adults with rheumatoid arthritis.","evidence":"Well-established"},{"condition":"Ankylosing spondylitis","description":"Helps relieve back pain and stiffness associated with ankylosing spondylitis.","evidence":"Well-established"},{"condition":"Acute gouty arthritis","description":"Provides rapid relief from pain and inflammation during acute gout attacks.","evidence":"Well-established"},{"condition":"Chronic low back pain","description":"May be used to manage chronic low back pain in some patients.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label to prevent migraines, but evidence is limited.","evidence":"Limited"},{"condition":"Postoperative pain","description":"Occasionally used off-label for short-term postoperative pain management.","evidence":"Limited"}]

Primary treatment for: Osteoarthritis

Also treats: Rheumatoid arthritis, Ankylosing spondylitis, Acute gouty arthritis

📋 Drug Information

Generic Name(s)Etoricoxib (90mg)
Brand Namezeexib 90 tablet
ManufacturerZeelab Pharmacy Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAID's -Selective COX-2 Inhibitors
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Stay well hydrated throughout the day.
3
Avoid alcohol while taking this medicine.
4
Do not take more than the prescribed dose.
5
Consult your doctor if symptoms persist beyond 7 days.
6
Report any unusual bleeding or bruising immediately.
7
Monitor your blood pressure regularly if you have hypertension.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Chronic joint pain
This medicine is commonly prescribed for this.
Likely Use
Fever
This medicine is not a primary fever reducer.
Not Primary
Acute gout attack
This medicine is effective for gout pain.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is well absorbed from the gastrointestinal tract after oral administration. The absolute bioavailability is approximately 100%.
DistributionThis medicine is widely distributed in the body. It has a volume of distribution of about 120 liters in adults.
Protein BindingThis medicine is highly bound to plasma proteins, approximately 92%.
MetabolismThis medicine is extensively metabolized in the liver, primarily by cytochrome P450 enzymes, including CYP3A4. Several metabolites are formed, which are inactive.
Half-LifeThe elimination half-life of this medicine is approximately 22 hours.
ExcretionThis medicine is excreted mainly in the urine (about 70%) and feces (about 20%), primarily as metabolites.
BioavailabilityThe oral bioavailability of this medicine is approximately 100%.
Onset of ActionPain relief typically begins within 30 to 60 minutes after oral administration.
Peak Plasma TimePeak plasma concentration is reached approximately 1 hour after oral administration.
Duration of ActionThe pain-relieving effect of this medicine lasts for about 24 hours, allowing once-daily dosing.

How It Works

This medicine works by selectively inhibiting the cyclooxygenase-2 (COX-2) enzyme. By blocking COX-2, it reduces the production of prostaglandins, which are chemicals that cause pain, inflammation, and fever. Because it is selective for COX-2 over COX-1, it is less likely to cause stomach irritation compared to non-selective NSAIDs, but it still carries cardiovascular risks.

Mechanism Steps

1
Selective COX-2 binding: This medicine selectively binds to and inhibits the COX-2 enzyme, which is induced during inflammation.
2
Reduced prostaglandin synthesis: Inhibition of COX-2 decreases the production of prostaglandins, which are mediators of pain and inflammation.
3
Relief of pain and swelling: The reduction in prostaglandins leads to decreased pain, swelling, and stiffness in affected joints.
4
Minimal COX-1 effect: Because it does not significantly inhibit COX-1, it has less impact on the stomach lining and platelet function compared to non-selective NSAIDs.

💡 How to Take zeexib 90 tablet

Strength: Etoricoxib 90 mg immediate-release tablet

1Take this medicine orally with a full glass of water.
2Take it with food or milk to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Take it at the same time each day.
5Do not take more than the prescribed dose.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 90 mg taken orally once daily for osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. For acute gouty arthritis, the recommended dose is 120 mg once daily. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine. Use with caution and monitor kidney function and blood pressure closely.
Renal ImpairmentNo dose adjustment is needed for mild renal impairment. For moderate to severe renal impairment, use is not recommended. Consult your doctor.
Hepatic ImpairmentFor mild hepatic impairment, no dose adjustment is needed. For moderate hepatic impairment, the dose should not exceed 60 mg once daily. For severe hepatic impairment, use is not recommended.
Maximum Daily DoseThe maximum recommended daily dose is 120 mg for acute gout, and 90 mg for other conditions.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of zeexib 90 tablet

✅ Common Side Effects

Headache (Common (5-10%))
Usually resolves on its own. Consult doctor if persistent or severe.
Dizziness (Common (1-5%))
Avoid driving or operating machinery until you know how it affects you.
Upset stomach (Common (1-5%))
Take with food or milk to reduce stomach upset.
Nausea (Common (1-5%))
Take with food. If nausea persists, consult your doctor.
Increased blood pressure (Common (1-5%))
Monitor your blood pressure regularly. Inform your doctor if it rises.

🚨 Serious Side Effects

Gastrointestinal bleeding or ulcer (Rare (<0.1%))
Seek immediate medical attention if you notice black stool, vomiting blood, or severe abdominal pain.
Heart attack or stroke (Rare (<0.1%))
Call emergency services if you experience chest pain, shortness of breath, or sudden weakness.
Kidney problems (Rare (<0.1%))
Report decreased urine output, swelling, or fatigue to your doctor immediately.
Severe allergic reaction (Rare (<0.1%))
Seek emergency help if you develop rash, swelling of face or throat, or difficulty breathing.

⚠️ Rare Side Effects

Liver damage
Report yellowing of skin or eyes, dark urine, or severe fatigue to your doctor.
Severe skin reactions
Seek immediate medical attention if you develop a blistering rash or peeling skin.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
ACE inhibitors Major
Diuretics Major
Lithium Major
Methotrexate Moderate
Corticosteroids Moderate
SSRIs Moderate
Antacids Minor

🚨 Major Interactions

  • Warfarin
  • ACE inhibitors or ARBs
  • Diuretics
  • Lithium

⚡ Moderate Interactions

  • Methotrexate
  • Corticosteroids
  • SSRIs

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine as it can increase the risk of stomach bleeding and liver problems.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["History of heart attack, stroke, or bypass surgery","Active stomach ulcer or gastrointestinal bleeding","Severe kidney disease","Severe liver disease","Allergy to etoricoxib or other NSAIDs","Pregnancy (third trimester)"]

⚠️ Warnings & Precautions

["Take with food to reduce stomach upset.","Avoid alcohol.","Do not exceed the recommended dose.","Inform your doctor if you have heart disease, high blood pressure, or kidney problems.","Do not use for minor aches without medical advice.","Long-term use should be under medical supervision."]

🤱 Lactation Safety

This medicine may pass into breast milk. It is not recommended during breastfeeding unless advised by a doctor.

💊 Overdose Management

If you suspect an overdose, seek emergency medical attention immediately. Symptoms may include severe stomach pain, vomiting, drowsiness, and difficulty breathing. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or take it for longer than advised. Take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine as it can increase the risk of stomach bleeding. Inform your doctor if you have a history of heart disease, high blood pressure, kidney or liver problems, or stomach ulcers. Do not take other NSAIDs or pain relievers without consulting your doctor. If you are pregnant or planning to become pregnant, talk to your doctor before taking this medicine. Regular monitoring of blood pressure and kidney function may be needed during long-term use.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of kidney problems, gastrointestinal bleeding, and cardiovascular events. Use with caution and monitor closely.

🤰 Pregnancy Planning (TTC)

This medicine should be avoided during pregnancy, especially in the third trimester. If you are planning pregnancy, consult your doctor for alternative pain relief options.

🏥 Post-Surgery Considerations

This medicine may be used for postoperative pain under medical supervision. Inform your surgeon if you are taking this medicine before surgery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may increase the risk of bleeding during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce joint stress.
🥗
Regular low-impact exercise like swimming.
😴
Practice good posture.
💧
Include anti-inflammatory foods in your diet.
🧘
Get adequate sleep.

🏋️ Exercise Considerations

Avoid high-impact exercises that may worsen joint pain. Consult your doctor or physiotherapist for an exercise plan suitable for your condition.

🥗 Diet Recommendations

Include omega-3 rich foods
Reduce processed food intake
Stay well hydrated

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience serious side effects, seek medical advice immediately.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of cardiovascular events, kidney problems, and gastrointestinal bleeding. Regular monitoring of blood pressure, kidney and liver function is recommended. Use the lowest effective dose for the shortest duration possible.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain.

Evidence: Well-established
Weight loss

Reduces stress on joints and improves symptoms.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. However, consult your doctor before receiving any vaccine while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and avoid extreme heat or cold. If traveling across time zones, consult your doctor about adjusting the timing of your dose. Keep it in your carry-on luggage to avoid loss.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic knee pain
Started this medicine as prescribed for osteoarthritis. Within 2 weeks noticed significant improvement in morning stiffness. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 60-year-old man with acute gout attack
Was prescribed this medicine for severe gout pain in his big toe. He experienced relief within a few hours and was able to walk comfortably by the next day. He was advised to avoid alcohol and drink plenty of water.
💡 Lesson: This medicine can provide rapid relief in acute gout, but lifestyle modifications are important to prevent future attacks.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine typically starts relieving pain within 30 to 60 minutes after taking it.

Q: Can I take it on an empty stomach?

A: It is best taken with food or milk to reduce the risk of stomach upset.

Q: Is it safe to take with other painkillers?

A: Do not take other NSAIDs or painkillers without consulting your doctor, as it may increase the risk of side effects.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for zeexib 90 tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Etoricoxib is a safe painkiller for everyone.
    Fact: It is not safe for people with heart disease, stomach ulcers, or kidney problems.
  • Myth: Etoricoxib can be taken without a prescription.
    Fact: It is a prescription medicine and should only be taken under a doctor's supervision.
  • Myth: Etoricoxib works instantly.
    Fact: It takes about 30-60 minutes to start relieving pain.

🔄 Alternative Options

Generic Alternatives

  • Etoricoxib 90 mg tablet (generic)

Brand Alternatives

  • Etoshine 90 Tablet
  • Etoshine 90mg Tablet
  • Etoricoxib 90mg Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Etoricoxib","class":"Selective COX-2 inhibitor","half_life":"22 hours","common_use":"Osteoarthritis, gout"},{"medicine":"Celecoxib","class":"Selective COX-2 inhibitor","half_life":"11 hours","common_use":"Osteoarthritis, rheumatoid arthritis"},{"medicine":"Diclofenac","class":"Non-selective NSAID","half_life":"1-2 hours","common_use":"Pain, inflammation"}]

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