aride 400mg tablet sr - Amisulpride (400mg) medicine

Aride 400mg Tablet SR - Uses, Price, Side Effects

4.7 (18 reviews)
Amisulpride (400mg)
๐Ÿญ Next Labs Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 21, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 21, 2026

What is aride 400mg tablet sr used for?

Aride 400mg Tablet SR contains Amisulpride, an atypical antipsychotic used to treat schizophrenia, especially positive and negative symptoms. It works by blocking dopamine receptors in the brain, helping to restore chemical balance and reduce hallucinations, delusions, and social withdrawal.

  • Generic Name: Amisulpride
  • Manufacturer: Next Labs Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š aride 400mg tablet sr Uses & Benefits

Schizophrenia (positive and negative symptoms); acute psychotic episodes; maintenance therapy.

Off-label uses: Bipolar depression, anxiety disorders, obsessive-compulsive disorder (limited evidence).

๐Ÿ“‹ Drug Information

Generic Name(s)Amisulpride
Brand NameAmisant 200 Tablet
ManufacturerNext Labs Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassAtypical Antipsychotics
Route of AdministrationOral
StorageStore at room temperature (15-30ยฐC), protected from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration, with peak plasma concentrations reached within 1-4 hours. Bioavailability is approximately 48% due to first-pass metabolism.
DistributionWidely distributed throughout the body; crosses the blood-brain barrier. Volume of distribution is about 5.8 L/kg.
Protein BindingApproximately 16% bound to plasma proteins.
MetabolismMetabolized in the liver, primarily via CYP3A4, to inactive metabolites. Minor metabolism via other pathways.
Half-LifeApproximately 12 hours (range 10-14 hours).
ExcretionPrimarily excreted in urine (about 70% as unchanged drug and metabolites) and feces (about 20%).
Bioavailability48%
Onset of ActionTherapeutic effects may be observed within a few days to weeks, but full antipsychotic effect may ta
Peak Plasma Time1-4 hours
Duration of ActionApproximately 24 hours due to once-daily dosing.

How It Works

Selective antagonist at dopamine D2 and D3 receptors, with higher affinity for D3 receptors. It also has some antagonistic activity at serotonin 5-HT2A receptors.

Mechanism Steps

1Amisulpride selectively binds to dopamine D2 and D3 receptors, with higher affinity for D3.
2Blocks dopamine receptors in the mesolimbic system, reducing positive symptoms of schizophrenia.
3At low doses, preferentially blocks presynaptic D2/D3 autoreceptors, increasing dopamine release in prefrontal cortex, improving negative symptoms.

๐Ÿ’ก How to Take aride 400mg tablet sr

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of aride 400mg tablet sr

โœ… Common Side Effects

  • Insomnia
  • Anxiety
  • Agitation
  • Weight gain
  • Constipation
  • Nausea
  • Dry mouth
  • Sedation

๐Ÿšจ Serious Side Effects

  • QT prolongation
  • Torsades de pointes
  • Neuroleptic malignant syndrome
  • Seizures
  • Tardive dyskinesia
  • Prolactin elevation (galactorrhea, gynecomastia)

โš ๏ธ Rare Side Effects

  • Hepatotoxicity
  • Agranulocytosis
  • Venous thromboembolism
  • Pancreatitis
  • Allergic reactions

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Levodopa Major Reduced effectiveness of levodopa
Antihypertensives Moderate Increased risk of hypotension
CNS depressants Moderate Enhanced sedative effects

๐Ÿšจ Major Interactions

  • Levodopa
  • Dopamine agonists
  • QT-prolonging drugs
  • CYP3A4 inhibitors

โšก Moderate Interactions

  • Antihypertensives
  • CNS depressants
  • Lithium

โ„น๏ธ Minor Interactions

  • Antacids
  • Cimetidine

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption but does not significantly affect bioavailability.

๐Ÿท Alcohol Interaction

Alcohol may enhance CNS depressant effects; avoid concurrent use.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Moderate
Kidney
Moderate
Heart
High
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity to amisulpride; concomitant use with prolactin-dependent tumors; known QT prolongation; severe renal impairment (CrCl <10 mL/min); pheochromocytoma.

๐Ÿ“Š Monitoring Parameters

ECG (QT interval), blood pressure, liver function tests, renal function, prolactin levels, extrapyramidal symptoms.

๐Ÿคฑ Lactation Safety

Not recommended; amisulpride is excreted in breast milk and may cause adverse effects in the infant.

๐Ÿ’Š Overdose Management

Supportive care; ECG monitoring; activated charcoal if recent ingestion; no specific antidote; treat arrhythmias as needed.

โฐ Missed Dose

Take as soon as remembered unless close to next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for aride 400mg tablet sr

View All

Alternative brands with exact same active ingredient (Amisulpride (400mg)):

Medical Note: Always consult your doctor before switching medications.

โญ User Reviews

Trusted Reviewer Jul 10, 2026

Effective and reliable. Worked as expected.

Verified User Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Certified Buyer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Verified User Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Verified User Jul 10, 2026

Found this to be a helpful product. Good results.

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