Arena 750mcg/75mg Tablet - Uses, Price, Side Effects
What is arena 750mcg/75mg tablet used for?
Arena 750mcg/75mg Tablet is a combination of Methylcobalamin (750mcg) and Pregabalin (75mg) used for neuropathic pain. Methylcobalamin helps in nerve regeneration, while Pregabalin reduces pain signals in the brain. It is prescribed for conditions like diabetic neuropathy, postherpetic neuralgia, and fibromyalgia. Take as directed by your doctor.
- Generic Name: Methylcobalamin + Pregabalin
- Manufacturer: Neiss Labs Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ arena 750mcg/75mg tablet Uses & Benefits
Diabetic neuropathy, postherpetic neuralgia, fibromyalgia, neuropathic pain associated with spinal cord injury.
Off-label uses: Generalized anxiety disorder, social anxiety disorder, restless legs syndrome.
๐ Drug Information
| Generic Name(s) | Methylcobalamin + Pregabalin |
| Brand Name | Axogurd-SR Tablet |
| Manufacturer | Neiss Labs Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Neurotropic vitamin + Gabapentinoid |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Methylcobalamin: Coenzyme for myelin synthesis; Pregabalin: Binds to alpha2-delta subunit of voltage-gated calcium channels, reducing calcium influx and neurotransmitter release.
Mechanism Steps
๐ก How to Take arena 750mcg/75mg tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of arena 750mcg/75mg tablet
โ Common Side Effects
- Dizziness
- Somnolence
- Dry mouth
- Edema
- Blurred vision
- Weight gain
- Constipation
๐จ Serious Side Effects
- Angioedema
- Hypersensitivity reactions
- Suicidal thoughts
- Rhabdomyolysis
- PR interval prolongation
โ ๏ธ Rare Side Effects
- Stevens-Johnson syndrome
- Hepatotoxicity
- Pancreatitis
- Blood dyscrasias
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Alcohol | Moderate | Increased dizziness and drowsiness |
| Opioid analgesics | Major | Additive CNS depression |
| ACE inhibitors | Minor | Possible increased risk of angioedema |
๐จ Major Interactions
- Central nervous system depressants
- Thalidomide
- Angiotensin-converting enzyme inhibitors
โก Moderate Interactions
- Oral hypoglycemics
- Antihypertensives
โน๏ธ Minor Interactions
- Antacids
- H2 blockers
๐ฝ๏ธ Food Interactions
High-fat meal may delay absorption of pregabalin
๐ท Alcohol Interaction
Additive CNS depression; avoid concurrent use.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to any component; severe renal impairment (CrCl <30 mL/min) for pregabalin.
๐ Monitoring Parameters
Renal function, liver function, CBC, signs of hypersensitivity, CNS depression, suicidal ideation.
๐คฑ Lactation Safety
Pregabalin excreted in breast milk; caution advised.
๐ Overdose Management
Supportive care; activated charcoal if recent ingestion; hemodialysis may remove pregabalin.
โฐ Missed Dose
Take as soon as remembered unless near next dose; skip missed dose if close to next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
This medicine was effective for me. I followed the doctor's advice.
Good quality medicine. Satisfied with the outcome.
Good quality medicine. Satisfied with the outcome.
Good quality medicine. Satisfied with the outcome.
Good quality medicine. Satisfied with the outcome.