arboh 12.5mg/20mg tablet
What is arboh 12.5mg/20mg tablet used for?
Arboh 12.5mg/20mg Tablet (Hydrochlorothiazide + Olmesartan Medoxomil) is used to treat CARDIAC. It contains Hydrochlorothiazide (12.5mg) + Olmesartan Medoxomil (20mg), which Hydrochlorothiazide inhibits sodium reabsorption in distal convoluted tubule, re. Always consult your doctor before use. Take as prescribed.
- Generic Name: Hydrochlorothiazide + Olmesartan Medoxomil
- Manufacturer: Three Dots Lifescience
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ arboh 12.5mg/20mg tablet Uses & Benefits
Hypertension (first-line or add-on therapy).
Off-label uses: Heart failure (olmesartan component), diabetic nephropathy (olmesartan), edema (hydrochlorothiazide).
๐ Drug Information
| Generic Name(s) | Hydrochlorothiazide + Olmesartan Medoxomil |
| Brand Name | Arboh 12.5mg/20mg Tablet |
| Manufacturer | Three Dots Lifescience |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Thiazide diuretic + Angiotensin II receptor blocker (ARB) |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Hydrochlorothiazide inhibits sodium reabsorption in distal convoluted tubule, reducing plasma volume. Olmesartan blocks angiotensin II AT1 receptors, causing vasodilation and reduced aldosterone secretion.
Mechanism Steps
๐ก How to Take arboh 12.5mg/20mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of arboh 12.5mg/20mg tablet
โ Common Side Effects
- Dizziness
- Headache
- Fatigue
- Hypokalemia
- Hyperuricemia
- Increased blood glucose
- Orthostatic hypotension
๐จ Serious Side Effects
- Acute renal failure
- Hyperkalemia
- Angioedema
- Stevens-Johnson syndrome
- Pancreatitis
- Acute angle-closure glaucoma
โ ๏ธ Rare Side Effects
- Hepatic impairment
- Leukopenia
- Thrombocytopenia
- Anaphylactic reaction
- Photosensitivity
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Lithium | Major | Increased lithium toxicity risk |
| NSAIDs | Major | Reduced antihypertensive effect, increased renal impairment risk |
| Potassium-sparing diuretics | Major | Hyperkalemia risk |
| ACE inhibitors | Major | Increased hypotension and hyperkalemia risk |
| Aliskiren | Major | Increased adverse effects in renal impairment |
| Digoxin | Moderate | Hypokalemia may increase digoxin toxicity |
| Antidiabetic agents | Moderate | Hydrochlorothiazide may increase blood glucose |
| Corticosteroids | Moderate | Increased electrolyte depletion |
| Cholestyramine | Moderate | Reduced absorption of hydrochlorothiazide |
| Colestipol | Moderate | Reduced absorption of hydrochlorothiazide |
| Alcohol | Minor | Potentiation of orthostatic hypotension |
| Barbiturates | Minor | Potentiation of orthostatic hypotension |
| Narcotics | Minor | Potentiation of orthostatic hypotension |
| Amphotericin B | Minor | Increased electrolyte depletion |
๐จ Major Interactions
- Lithium
- NSAIDs
- Potassium-sparing diuretics
- ACE inhibitors
- Aliskiren
โก Moderate Interactions
- Digoxin
- Antidiabetic agents
- Corticosteroids
- Cholestyramine
- Colestipol
โน๏ธ Minor Interactions
- Alcohol
- Barbiturates
- Narcotics
- Amphotericin B
๐ฝ๏ธ Food Interactions
High-fat meals may reduce olmesartan absorption. Avoid potassium-rich foods.
๐ท Alcohol Interaction
May potentiate orthostatic hypotension.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Anuria, hypersensitivity to sulfonamides or ARBs, severe renal impairment (CrCl <30 mL/min), pregnancy (2nd/3rd trimester), concomitant aliskiren in diabetes.
๐ Monitoring Parameters
Blood pressure, serum electrolytes (especially potassium, sodium), renal function, blood glucose, uric acid.
๐คฑ Lactation Safety
Hydrochlorothiazide excreted in milk; olmesartan unknown. Avoid use during breastfeeding.
๐ Overdose Management
Symptomatic and supportive; monitor electrolytes, blood pressure, and renal function. Induce emesis or gastric lavage if recent. Administer IV fluids and pressors if needed.
โฐ Missed Dose
Take as soon as remembered unless near next dose; skip missed dose if close to next dose. Do not double dose.
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
This medicine was effective for me. I followed the doctor's advice.
Effective and reliable. Worked as expected.
Found this to be a helpful product. Good results.
Good quality medicine. Satisfied with the outcome.
Helpful and effective medicine as per my experience. Always consult a doctor.