am dot 5mg tablet - Amlodipine (5mg) medicine

Am Dot 5mg Tablet - Uses, Price, Side Effects

4.7 (10 reviews)

Amlodipine (5mg)

🏭 Three Dots Lifescience 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 23, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 23, 2026

What is am dot 5mg tablet used for?

Am Dot 5mg Tablet contains Amlodipine, a calcium channel blocker used to treat high blood pressure and chest pain (angina). It works by relaxing blood vessels, making it easier for the heart to pump blood. Take it as prescribed, usually once daily, with or without food.

Generic Name: Amlodipine
Manufacturer: Three Dots Lifescience
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 am dot 5mg tablet Uses & Benefits

Hypertension, chronic stable angina, vasospastic angina (Prinzmetal's angina).

Off-label uses: Raynaud's phenomenon, migraine prophylaxis, high-altitude pulmonary edema.

📋 Drug Information

Generic Name(s)	Amlodipine
Brand Name	Amlokind 5 Tablet
Manufacturer	Three Dots Lifescience
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	CARDIAC
Action Class	Calcium channel blockers- Dihydropyridines (DHP)
Route of Administration	Oral.
Storage	Store at 20-25°C (68-77°F); protect from light and moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed after oral administration with peak plasma concentrations achieved within 6-12 hours.

DistributionExtensively distributed with a large volume of distribution (about 21 L/kg).

Protein BindingApproximately 93% bound to plasma proteins.

MetabolismExtensively metabolized in the liver via CYP3A4 isoenzyme to inactive metabolites.

Half-Life30-50 hours (terminal elimination half-life).

ExcretionPrimarily excreted as metabolites in urine (about 60%) and feces (20-25%).

Bioavailability64-90% (oral bioavailability).

Onset of ActionGradual onset; antihypertensive effect seen within 2-4 hours.

Peak Plasma Time6-12 hours.

Duration of Action24 hours (once-daily dosing).

How It Works

Inhibits calcium ion influx across cardiac and vascular smooth muscle cells, leading to vasodilation and reduced peripheral vascular resistance.

Mechanism Steps

1Binds to L-type calcium channels in vascular smooth muscle and cardiac myocytes.

2Inhibits calcium ion influx during depolarization.

3Reduces intracellular calcium concentration.

💡 How to Take am dot 5mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

⚠️ Side Effects of am dot 5mg tablet

✅ Common Side Effects

Edema (peripheral)
Dizziness
Flushing
Palpitations
Fatigue
Nausea

🚨 Serious Side Effects

Severe hypotension
Myocardial infarction (rare)
Hepatotoxicity (rare)
Stevens-Johnson syndrome (rare)

⚠️ Rare Side Effects

Gingival hyperplasia
Gynecomastia
Leukopenia
Vasculitis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Grapefruit juice	Moderate	Increased amlodipine levels
Simvastatin	Moderate	Increased risk of muscle injury
Cyclosporine	Moderate	Increased cyclosporine levels

🚨 Major Interactions

CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir)
CYP3A4 inducers (e.g., rifampin, carbamazepine)
Simvastatin

⚡ Moderate Interactions

Grapefruit juice
Diltiazem
Clarithromycin

ℹ️ Minor Interactions

Antacids
Sildenafil

🍽️ Food Interactions

Grapefruit juice may increase amlodipine levels.

🍷 Alcohol Interaction

Alcohol may potentiate the hypotensive effect.

🛡️ Safety & Warnings

Liver

Low

Kidney

Low

Heart

Low

Pregnancy

Category A

🚫 Contraindications

Hypersensitivity to amlodipine or dihydropyridines, severe hypotension, cardiogenic shock.

📊 Monitoring Parameters

Blood pressure, heart rate, peripheral edema, liver function tests.

🤱 Lactation Safety

Excreted in breast milk; caution advised.

💊 Overdose Management

Gastric lavage, activated charcoal, supportive care; calcium gluconate may be beneficial.

⏰ Missed Dose

Take as soon as remembered; if close to next dose, skip missed dose. Do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

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🔄 Substitutes for am dot 5mg tablet

View All

Alternative brands with exact same active ingredient (Amlodipine (5mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Regular Customer Jul 10, 2026

Effective and reliable. Worked as expected.

Certified Buyer Jul 10, 2026

Found this to be a helpful product. Good results.

Verified User Jul 10, 2026