arasid 500mg injection - Uses, Price, Side Effects & Substitutes
What is arasid 500mg injection used for?
Arasid 1000mg Injection (Cytarabine) is used to treat ANTI NEOPLASTICS. It contains Cytarabine (500mg), which Cytarabine is a pyrimidine nucleoside analog that inhibits DNA synthesis by comp. Always consult your doctor before use. Take as prescribed.
- Generic Name: Cytarabine
- Manufacturer: Intas Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ arasid 500mg injection Uses & Benefits
Acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), chronic myeloid leukemia (CML), non-Hodgkin lymphoma, meningeal leukemia.
Off-label uses: Myelodysplastic syndromes, solid tumors (e.g., ovarian cancer).
๐ Drug Information
| Generic Name(s) | Cytarabine |
| Brand Name | Arasid 1000mg Injection |
| Manufacturer | Intas Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Antimetabolites |
| Route of Administration | Intravenous (IV) infusion or intrathecal. |
| Storage | Store at 20-25ยฐC (68-77ยฐF). Protect from light. Do not freeze. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Cytarabine is a pyrimidine nucleoside analog that inhibits DNA synthesis by competing with cytidine for incorporation into DNA, leading to chain termination and cell death.
Mechanism Steps
๐ก How to Take arasid 500mg injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of arasid 500mg injection
โ Common Side Effects
- Myelosuppression
- Nausea
- Vomiting
- Diarrhea
- Mucositis
- Fever
- Rash
๐จ Serious Side Effects
- Severe myelosuppression
- Infections
- Hepatotoxicity
- Neurotoxicity (cerebellar dysfunction)
- Acute respiratory distress syndrome (ARDS)
- Tumor lysis syndrome
โ ๏ธ Rare Side Effects
- Pancreatitis
- Pericarditis
- Anaphylaxis
- Hemolytic uremic syndrome
- Leukoencephalopathy
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Methotrexate | Major | Increased toxicity, especially hepatotoxicity and myelosuppression. |
| Flucytosine | Major | Antagonism of antifungal effect. |
| Cyclophosphamide | Major | Increased cardiotoxicity risk. |
| Vincristine | Major | Increased neurotoxicity. |
| Digoxin | Moderate | Reduced digoxin absorption. |
| Phenytoin | Moderate | Reduced phenytoin levels. |
| Warfarin | Moderate | Altered anticoagulation effect. |
| Allopurinol | Minor | Possible increased cytarabine toxicity. |
| Acetaminophen | Minor | Possible increased hepatotoxicity. |
๐จ Major Interactions
- Methotrexate
- Flucytosine
- Cyclophosphamide
- Vincristine
โก Moderate Interactions
- Digoxin
- Phenytoin
- Warfarin
โน๏ธ Minor Interactions
- Allopurinol
- Acetaminophen
๐ฝ๏ธ Food Interactions
No significant food interactions.
๐ท Alcohol Interaction
Avoid alcohol due to increased hepatotoxicity risk.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to cytarabine, severe bone marrow suppression, active infection, pregnancy.
๐ Monitoring Parameters
Complete blood count (CBC), liver function tests (LFTs), renal function tests, neurological assessment.
๐คฑ Lactation Safety
Not recommended; excreted in breast milk.
๐ Overdose Management
Supportive care; monitor for myelosuppression, neurotoxicity, and hepatotoxicity. No specific antidote.
โฐ Missed Dose
Contact healthcare provider; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for arasid 500mg injection
View AllAlternative brands with exact same active ingredient (Cytarabine (500mg)):
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cytalon 500 injectionCelon Laboratories Ltd โน485.71 15.1% CHEAPER
-
biobin 500mg injectionBiochem Pharmaceutical Industries โน488.57 14.6% CHEAPER
-
oncotar 500mg injectionUnited Biotech Pvt Ltd โน495.00 13.5% CHEAPER
-
cytraze 500mg injectionKhandelwal Laboratories Pvt Ltd โน540.00 5.6% CHEAPER
-
Remcyta 500mg InjectionAlkem Laboratories Ltd โน541.31 5.4% CHEAPER
-
cytowel 500mg injectionGetwell Oncology Pvt Ltd โน550.00 3.8% CHEAPER
-
cytaraside 500mg injectionChandra Bhagat Pharma Pvt Ltd โน590.00 3.1% COSTLIER
-
cytarine 500mg injectionFresenius Kabi India Pvt Ltd โน593.46 3.8% COSTLIER
-
cybin pf 500mg injectionVhb Life Sciences Inc โน619.00 8.2% COSTLIER
-
cytosar 500mg injectionPfizer Ltd โน1,089.50 90.5% COSTLIER
Medical Note: Always consult your doctor before switching medications.