appime 500mg injection - Uses, Price, Side Effects & Substitutes
What is appime 500mg injection used for?
Appime 250mg Injection (Cefepime) is used to treat ANTI INFECTIVES. It contains Cefepime (500mg), which Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins. Always consult your doctor before use. Take as prescribed.
- Generic Name: Cefepime
- Manufacturer: Apkavit Lifesciences
- Form: Allopathy
- Pregnancy Category: B
- Prescription Required: Yes
๐ appime 500mg injection Uses & Benefits
Treatment of pneumonia, urinary tract infections, skin and soft tissue infections, intra-abdominal infections, febrile neutropenia.
Off-label uses: Meningitis, Osteomyelitis
๐ Drug Information
| Generic Name(s) | Cefepime |
| Brand Name | Appime 250mg Injection |
| Manufacturer | Apkavit Lifesciences |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporins: 4th generation |
| Route of Administration | Intravenous (IV) or intramuscular (IM) |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to cell lysis.
Mechanism Steps
๐ก How to Take appime 500mg injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of appime 500mg injection
โ Common Side Effects
- Diarrhea
- Nausea
- Vomiting
- Rash
- Injection site reactions
๐จ Serious Side Effects
- Anaphylaxis
- Clostridioides difficile colitis
- Seizures
- Acute renal failure
โ ๏ธ Rare Side Effects
- Hemolytic anemia
- Agranulocytosis
- Stevens-Johnson syndrome
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Aminoglycosides | Major | Increased risk of nephrotoxicity and ototoxicity |
| Loop diuretics | Major | Increased risk of nephrotoxicity |
| Probenecid | Major | Decreased renal excretion of cefepime, increased plasma levels |
| Warfarin | Moderate | Possible increased INR |
| Oral contraceptives | Moderate | Reduced efficacy of contraceptives |
| Antacids | Minor | No significant interaction |
๐จ Major Interactions
- Aminoglycosides
- Loop diuretics
- Probenecid
โก Moderate Interactions
- Warfarin
- Oral contraceptives
โน๏ธ Minor Interactions
- Antacids
๐ฝ๏ธ Food Interactions
No significant food interactions.
๐ท Alcohol Interaction
No known interaction.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to cefepime or other cephalosporins, penicillins, or beta-lactam antibiotics.
๐ Monitoring Parameters
Renal function, complete blood count, signs of hypersensitivity, superinfection.
๐คฑ Lactation Safety
Excreted in breast milk in low concentrations; use with caution.
๐ Overdose Management
Supportive care; hemodialysis may enhance elimination.
โฐ Missed Dose
Administer as soon as remembered; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for appime 500mg injection
View AllAlternative brands with exact same active ingredient (Cefepime (500mg)):
-
biopime 500mg injectionBiochem Pharmaceutical Industries โน64.85 45.5% CHEAPER
-
cepime 500mg injectionAlembic Pharmaceuticals Ltd โน67.41 43.4% CHEAPER
-
natapime 500mg injectionAncalima Lifesciences Ltd โน80.00 32.8% CHEAPER
-
cefeprime 500mg injectionVeritaz Healthcare Ltd โน83.13 30.1% CHEAPER
-
abdopime 500mg injectionOdin Healthcare Pvt Ltd โน84.38 29.1% CHEAPER
-
maxopime 500mg injectionParenteral Drugs India Ltd โน86.18 27.6% CHEAPER
-
corpime 500mg injectionCoral Pharmaceuticals P Ltd โน86.25 27.5% CHEAPER
-
winpime 500mg injectionConcept Pharmaceuticals Ltd โน89.00 25.2% CHEAPER
-
maxicef 500mg injectionAristo Pharmaceuticals Pvt Ltd โน89.46 24.8% CHEAPER
-
megapime 500mg injectionAlkem Laboratories Ltd โน90.00 24.4% CHEAPER
Medical Note: Always consult your doctor before switching medications.