Appedine Syrup - Uses, Price, Side Effects
What is appedine syrup used for?
Appedine Syrup is a combination of Cyproheptadine (an antihistamine with appetite-stimulating properties) and Tricholine Citrate (a liver tonic). It is used to increase appetite and support liver function in conditions like loss of appetite, malnutrition, and liver disorders. Cyproheptadine blocks serotonin and histamine receptors, stimulating hunger, while Tricholine Citrate aids fat metabolism and liver health.
- Generic Name: Cyproheptadine + Tricholine Citrate
- Manufacturer: Alencure Biotech Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ appedine syrup Uses & Benefits
Appetite stimulation, weight gain, allergic conditions, liver support
Off-label uses: Migraine prophylaxis, pruritus, serotonin syndrome adjunct
๐ Drug Information
| Generic Name(s) | Cyproheptadine + Tricholine Citrate |
| Brand Name | Aptimust Syrup |
| Manufacturer | Alencure Biotech Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | VITAMINS MINERALS NUTRIENTS |
| Action Class | Appetite Stimulant, Antihistamine, Hepatoprotective |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Cyproheptadine blocks histamine H1 receptors and serotonin 5-HT2 receptors, stimulating appetite; Tricholine Citrate provides choline for liver function and acts as a lipotropic agent.
Mechanism Steps
๐ก How to Take appedine syrup
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of appedine syrup
โ Common Side Effects
- Drowsiness
- Dry mouth
- Dizziness
- Increased appetite
- Weight gain
๐จ Serious Side Effects
- Seizures
- Hallucinations
- Urinary retention
- Blurred vision
- Tachycardia
โ ๏ธ Rare Side Effects
- Agranulocytosis
- Hemolytic anemia
- Thrombocytopenia
- Cholestatic jaundice
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | Increased risk of serotonin syndrome |
| CNS depressants | Moderate | Enhanced sedative effects |
| Anticholinergics | Moderate | Additive anticholinergic effects |
๐จ Major Interactions
- MAOIs
- CNS depressants
- Anticholinergics
โก Moderate Interactions
- Antihypertensives
- SSRIs
- Alcohol
โน๏ธ Minor Interactions
- Antacids
- Corticosteroids
๐ฝ๏ธ Food Interactions
Grapefruit juice may increase cyproheptadine levels
๐ท Alcohol Interaction
Increased CNS depression
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, narrow-angle glaucoma, urinary retention, severe hypertension, concurrent MAOI use
๐ Monitoring Parameters
Appetite, weight, liver function tests, sedation level
๐คฑ Lactation Safety
Excreted in breast milk; avoid or use with caution
๐ Overdose Management
Gastric lavage, activated charcoal, supportive care; for anticholinergic symptoms, physostigmine may be used
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose; do not double dose