aocin th 60mg/4mg tablet
What is aocin th 60mg/4mg tablet used for?
Alock E TH 60mg/4mg Tablet (Etoricoxib + Thiocolchicoside) is used to treat PAIN ANALGESICS. It contains Etoricoxib (60mg) + Thiocolchicoside (4mg), which Etoricoxib selectively inhibits COX-2, reducing prostaglandin synthesis; Thiocol. Always consult your doctor before use. Take as prescribed.
- Generic Name: Etoricoxib + Thiocolchicoside
- Manufacturer: Astonea Labs Private Limited
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ aocin th 60mg/4mg tablet Uses & Benefits
Acute musculoskeletal pain, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle spasms.
Off-label uses: Chronic low back pain, fibromyalgia (limited evidence).
๐ Drug Information
| Generic Name(s) | Etoricoxib + Thiocolchicoside |
| Brand Name | Alock E TH 60mg/4mg Tablet |
| Manufacturer | Astonea Labs Private Limited |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID + Muscle Relaxant |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture and light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Etoricoxib selectively inhibits COX-2, reducing prostaglandin synthesis; Thiocolchicoside acts as a GABA-A receptor agonist and glycine receptor agonist, producing muscle relaxation.
Mechanism Steps
๐ก How to Take aocin th 60mg/4mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of aocin th 60mg/4mg tablet
โ Common Side Effects
- Nausea
- Dyspepsia
- Diarrhea
- Headache
- Dizziness
- Somnolence
๐จ Serious Side Effects
- GI bleeding
- Cardiovascular events (MI, stroke)
- Hepatotoxicity
- Renal failure
- Anaphylaxis
โ ๏ธ Rare Side Effects
- Stevens-Johnson syndrome
- Toxic epidermal necrolysis
- Aplastic anemia
- Seizures
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Methotrexate | Major | Increased methotrexate toxicity |
| Lithium | Major | Increased lithium levels and toxicity |
| ACE inhibitors | Major | Reduced antihypertensive effect |
| Diuretics | Major | Reduced diuretic effect, increased nephrotoxicity |
| Aspirin | Major | Increased GI bleeding risk |
| Ketoconazole | Moderate | Increased etoricoxib levels |
| Rifampin | Moderate | Decreased etoricoxib levels |
| Antacids | Minor | Slight decrease in absorption |
๐จ Major Interactions
- Warfarin
- Methotrexate
- Lithium
- ACE inhibitors
- Diuretics
- Aspirin
โก Moderate Interactions
- CYP3A4 inhibitors (e.g., ketoconazole)
- CYP3A4 inducers (e.g., rifampin)
- Anticoagulants
- Antiplatelets
โน๏ธ Minor Interactions
- Antacids
- Corticosteroids
๐ฝ๏ธ Food Interactions
Food may delay absorption of etoricoxib but does not affect extent; thiocolchicoside absorption unaffected.
๐ท Alcohol Interaction
Increased risk of gastrointestinal bleeding and hepatotoxicity.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, pregnancy, breastfeeding, severe hepatic/renal impairment, active peptic ulcer, history of asthma, CV disease (etoricoxib), myasthenia gravis (thiocolchicoside).
๐ Monitoring Parameters
Liver function, renal function, blood pressure, signs of GI bleeding, cardiovascular status.
๐คฑ Lactation Safety
Not recommended; both drugs excreted in breast milk.
๐ Overdose Management
Symptomatic and supportive; no specific antidote. Induce emesis or gastric lavage if recent.
โฐ Missed Dose
Take as soon as remembered; skip if almost time for next dose. Do not double dose.
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Good quality medicine. Satisfied with the outcome.
This medicine was effective for me. I followed the doctor's advice.
This medicine was effective for me. I followed the doctor's advice.
Good quality medicine. Satisfied with the outcome.
Found this to be a helpful product. Good results.