alfuzin d 10mg/0.5mg tablet er - Alfuzosin (10mg) + Dutasteride (0.5mg) medicine

alfuzin d 10mg/0.5mg tablet er

4.4 (10 reviews)
๐Ÿญ Astonea Labs Private Limited ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 21, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 21, 2026

What is alfuzin d 10mg/0.5mg tablet er used for?

Alfugress-D Tablet SR (Alfuzosin + Dutasteride) is used to treat UROLOGY. It contains Alfuzosin (10mg) + Dutasteride (0.5mg), which Alfuzosin: Blocks alpha-1 adrenoceptors in prostate/bladder neck; Dutasteride: I. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Alfuzosin + Dutasteride
  • Manufacturer: Astonea Labs Private Limited
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š alfuzin d 10mg/0.5mg tablet er Uses & Benefits

Benign prostatic hyperplasia (BPH)

Off-label uses: Male pattern baldness (dutasteride alone)

๐Ÿ“‹ Drug Information

Generic Name(s)Alfuzosin + Dutasteride
Brand NameAlfugress-D Tablet SR
ManufacturerAstonea Labs Private Limited
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassUROLOGY
Action ClassAlpha-1 adrenergic blocker + 5-alpha-reductase inhibitor
Route of AdministrationOral
StorageStore at 20-25ยฐC, protect from light and moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionAlfuzosin: Rapidly absorbed; Dutasteride: Well absorbed
DistributionAlfuzosin: Vd 3.2 L/kg; Dutasteride: Vd 300-500 L
Protein BindingAlfuzosin: 82-90%; Dutasteride: >99%
MetabolismAlfuzosin: Hepatic (CYP3A4); Dutasteride: Hepatic (CYP3A4, CYP3A5)
Half-LifeAlfuzosin: 5-7 hours; Dutasteride: 5 weeks
ExcretionAlfuzosin: 75% feces, 24% urine; Dutasteride: Feces (mainly), urine (<1%)
BioavailabilityAlfuzosin: 49%; Dutasteride: 60%
Onset of ActionAlfuzosin: 1-2 hours; Dutasteride: 2 weeks
Peak Plasma TimeAlfuzosin: 8 hours (ER); Dutasteride: 2-3 hours
Duration of ActionAlfuzosin: 24 hours; Dutasteride: 24 hours (steady state months)

How It Works

Alfuzosin: Blocks alpha-1 adrenoceptors in prostate/bladder neck; Dutasteride: Inhibits 5-alpha-reductase, reducing DHT

Mechanism Steps

1Alfuzosin binds to alpha-1 adrenoceptors in prostate and bladder neck smooth muscle
2Blocks norepinephrine binding, causing smooth muscle relaxation
3Reduces urethral resistance and improves urine flow

๐Ÿ’ก How to Take alfuzin d 10mg/0.5mg tablet er

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of alfuzin d 10mg/0.5mg tablet er

โœ… Common Side Effects

  • Dizziness
  • Headache
  • Fatigue
  • Nasopharyngitis
  • Decreased libido
  • Erectile dysfunction
  • Ejaculation disorders

๐Ÿšจ Serious Side Effects

  • Orthostatic hypotension
  • Syncope
  • Priapism
  • Breast cancer (rare)

โš ๏ธ Rare Side Effects

  • Angioedema
  • Hepatotoxicity
  • Depression

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Ketoconazole Major Increased alfuzosin/dutasteride levels
Warfarin Moderate Increased INR
Cimetidine Moderate Increased dutasteride levels

๐Ÿšจ Major Interactions

  • CYP3A4 inhibitors (ketoconazole, ritonavir)
  • Other alpha-blockers
  • Antihypertensives

โšก Moderate Interactions

  • Cimetidine
  • Warfarin
  • CYP3A4 inducers

โ„น๏ธ Minor Interactions

  • Digoxin
  • Theophylline

๐Ÿฝ๏ธ Food Interactions

Alfuzosin: Food increases absorption; Dutasteride: No significant effect

๐Ÿท Alcohol Interaction

May increase hypotension risk

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity, severe hepatic impairment, orthostatic hypotension, women/children

๐Ÿ“Š Monitoring Parameters

Blood pressure, prostate-specific antigen (PSA), liver function

๐Ÿคฑ Lactation Safety

Not recommended; Dutasteride excreted in breast milk

๐Ÿ’Š Overdose Management

Symptomatic and supportive; hypotension treatment

โฐ Missed Dose

Take as soon as remembered; skip if near next dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

๐Ÿ”— View Profile

โญ User Reviews

Regular Customer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Regular Customer Jul 10, 2026

Effective and reliable. Worked as expected.

Verified User Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Happy Patient Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Certified Buyer Jul 10, 2026

Effective and reliable. Worked as expected.

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