anurab it 20mg/150mg tablet - Rabeprazole (20mg) + Itopride (150mg) medicine

anurab it 20mg/150mg tablet

4.3 (9 reviews)
๐Ÿญ Drukst Biotech Private Limited ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is anurab it 20mg/150mg tablet used for?

Aciflux 20 mg/150 mg capsule (Rabeprazole + Itopride) is used to treat GASTRO INTESTINAL. It contains Rabeprazole (20mg) + Itopride (150mg), which Rabeprazole inhibits gastric H+/K+ ATPase, reducing acid secretion; Itopride enh. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Rabeprazole + Itopride
  • Manufacturer: Drukst Biotech Private Limited
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š anurab it 20mg/150mg tablet Uses & Benefits

Gastroesophageal reflux disease (GERD), dyspepsia, gastroparesis.

Off-label uses: Functional dyspepsia, chronic gastritis.

๐Ÿ“‹ Drug Information

Generic Name(s)Rabeprazole + Itopride
Brand NameAciflux 20 mg/150 mg capsule
ManufacturerDrukst Biotech Private Limited
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassProton Pump Inhibitor + Prokinetic Agent
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRabeprazole: Rapidly absorbed after oral administration; Itopride: Well absorbed orally.
DistributionRabeprazole: Volume of distribution ~0.3 L/kg; Itopride: Distributed widely.
Protein BindingRabeprazole: ~96%; Itopride: ~96%.
MetabolismRabeprazole: Hepatic via CYP2C19 and CYP3A4; Itopride: Hepatic via flavin-containing monooxygenase.
Half-LifeRabeprazole: 1-2 hours; Itopride: 6 hours.
ExcretionRabeprazole: 90% renal as metabolites; Itopride: 60% renal, 30% fecal.
BioavailabilityRabeprazole: ~52%; Itopride: ~60%.
Onset of ActionRabeprazole: 1 hour; Itopride: 30-60 minutes.
Peak Plasma TimeRabeprazole: 2-4 hours; Itopride: 1-2 hours.
Duration of ActionRabeprazole: Up to 24 hours; Itopride: 6-8 hours.

How It Works

Rabeprazole inhibits gastric H+/K+ ATPase, reducing acid secretion; Itopride enhances gastric motility via dopamine D2 receptor antagonism and acetylcholinesterase inhibition.

Mechanism Steps

1Rabeprazole accumulates in parietal cell canaliculi and protonates to active form.
2Active rabeprazole binds covalently to H+/K+ ATPase, inhibiting acid secretion.
3Itopride antagonizes D2 receptors in the GI tract, enhancing acetylcholine release.

๐Ÿ’ก How to Take anurab it 20mg/150mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of anurab it 20mg/150mg tablet

โœ… Common Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Abdominal pain
  • Flatulence

๐Ÿšจ Serious Side Effects

  • Clostridium difficile infection
  • Fractures (long-term)
  • Hypomagnesemia
  • Interstitial nephritis

โš ๏ธ Rare Side Effects

  • Gynecomastia
  • Hepatotoxicity
  • Stevens-Johnson syndrome

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Atazanavir Major Reduced absorption of atazanavir
Rilpivirine Major Reduced absorption of rilpivirine
Methotrexate Major Increased methotrexate toxicity
Cilostazol Major Increased cilostazol levels
Warfarin Moderate Increased INR
Clopidogrel Moderate Reduced clopidogrel efficacy
Digoxin Moderate Increased digoxin levels
Iron salts Moderate Reduced iron absorption
Antacids Minor Reduced absorption of rabeprazole
Sucralfate Minor Reduced absorption of rabeprazole

๐Ÿšจ Major Interactions

  • Atazanavir
  • Rilpivirine
  • Methotrexate
  • Cilostazol

โšก Moderate Interactions

  • Warfarin
  • Clopidogrel
  • Digoxin
  • Iron salts

โ„น๏ธ Minor Interactions

  • Antacids
  • Sucralfate

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption of rabeprazole; itopride absorption unaffected.

๐Ÿท Alcohol Interaction

No significant interaction.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity, concurrent use with atazanavir or rilpivirine, gastrointestinal hemorrhage, obstruction, or perforation.

๐Ÿ“Š Monitoring Parameters

Symptoms of GI discomfort, liver function tests, magnesium levels (long-term).

๐Ÿคฑ Lactation Safety

Not recommended; excretion in milk unknown.

๐Ÿ’Š Overdose Management

Symptomatic and supportive treatment; no specific antidote.

โฐ Missed Dose

Take as soon as remembered; skip if near next dose. Do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

โญ User Reviews

Regular Customer Jul 10, 2026

Found this to be a helpful product. Good results.

Verified User Jul 10, 2026

Effective and reliable. Worked as expected.

Verified User Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Happy Patient Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Certified Buyer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

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