Aciflux 20 mg/150 mg Capsule: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in vomit or black, tarry stools
- Severe abdominal pain or cramping
- Difficulty breathing or swelling of face, lips, or throat
- Chest pain or palpitations
- Severe, persistent diarrhea with fever
- Unusual muscle stiffness, tremors, or difficulty walking
- Yellowing of skin or eyes (jaundice)
- Decreased urine output or swelling in legs
If experiencing severe symptoms, call emergency services immediately.
What is anurab it 20mg/150mg tablet used for?
This medicine is a combination of Rabeprazole (20 mg) and Itopride (150 mg) used to treat acid reflux, GERD, and functional dyspepsia. It works by reducing stomach acid and improving gut motility. It is taken orally once daily before breakfast. Do not use without a prescription.
- Generic Name: Rabeprazole + Itopride
- Manufacturer: Drukst Biotech Private Limited
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 anurab it 20mg/150mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा रैबेप्राजोल और आइटोप्राइड का संयोजन है, जिसका उपयोग एसिड रिफ्लक्स, जीईआरडी, और कार्यात्मक अपच के इलाज के लिए किया जाता है। यह पेट में एसिड का उत्पादन कम करती है और पाचन तंत्र की गति को बढ़ाती है। यह दवा सूजन, पेट फूलना, और जलन जैसे लक्षणों में राहत देती है। इसे सुबह नाश्ते से 30 मिनट पहले खाली पेट लेना चाहिए।
साइड इफेक्ट्स: आम दुष्प्रभावों में सिरदर्द, दस्त, पेट दर्द, मतली और मुँह सूखना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, गंभीर दस्त, या मांसपेशियों में अकड़न हो सकती है। किसी भी असामान्य लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे निगलें, चबाएं नहीं। खाली पेट सुबह नाश्ते से पहले लें। शराब का सेवन न करें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। दवा को बच्चों से दूर रखें।
💊 anurab it 20mg/150mg tablet Uses & Benefits
[{"condition":"Gastroesophageal reflux disease (GERD)","description":"Reduces stomach acid and improves gastric emptying, relieving heartburn, regurgitation, and chest discomfort.","evidence":"Well-established"},{"condition":"Functional dyspepsia","description":"Helps alleviate symptoms like post-meal fullness, upper abdominal bloating, and early satiety by enhancing gut motility and reducing acid.","evidence":"Well-established"},{"condition":"Peptic ulcer disease","description":"Used to promote ulcer healing by suppressing acid secretion and improving gastric motility.","evidence":"Moderate"},{"condition":"Gastritis","description":"Provides relief from inflammation-related symptoms by reducing acid exposure to the stomach lining.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Diabetic gastroparesis","description":"Sometimes prescribed to improve gastric emptying in patients with delayed stomach emptying due to diabetes.","evidence":"Limited"},{"condition":"Refractory nausea and vomiting","description":"May be used off-label when standard antiemetics are ineffective, due to itopride's prokinetic effects.","evidence":"Limited"}]
Primary treatment for: Gastroesophageal reflux disease (GERD)
Also treats: Functional dyspepsia, Peptic ulcer disease, Gastritis, Diabetic gastroparesis
📋 Drug Information
| Generic Name(s) | Rabeprazole + Itopride |
| Brand Name | Aciflux 20 mg/150 mg capsule |
| Manufacturer | Drukst Biotech Private Limited |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Proton Pump Inhibitor + Prokinetic Agent |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container, tightly closed. Do not refrigerate unless specified. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary actions. Rabeprazole is a proton pump inhibitor that irreversibly blocks the hydrogen-potassium ATPase enzyme in gastric parietal cells, thereby suppressing both basal and stimulated acid secretion. Itopride is a prokinetic agent that works by blocking dopamine D2 receptors and inhibiting acetylcholinesterase, which increases acetylcholine levels in the gastrointestinal tract. This dual action enhances gastric motility, accelerates gastric emptying, and improves coordination between the stomach and small intestine. The combination addresses both acid hypersecretion and impaired motility, which often coexist in functional gastrointestinal disorders.
Mechanism Steps
💡 How to Take anurab it 20mg/150mg tablet
Strength: Capsule containing Rabeprazole 20 mg and Itopride 150 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one capsule taken orally once daily, preferably on an empty stomach at least 30 minutes before breakfast. However, the dose and duration of treatment must be individualized by a qualified clinician based on the specific indication, severity of symptoms, age, weight, and renal and hepatic function. For GERD, treatment may last 4 to 8 weeks. For functional dyspepsia, it may be used for 2 to 4 weeks. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the side effects of this medicine, particularly extrapyramidal symptoms from Itopride. Dose adjustment may be necessary based on renal and hepatic function. Use with caution and monitor closely. |
| Renal Impairment | In patients with mild to moderate renal impairment, no dose adjustment is required. In severe renal impairment (creatinine clearance less than 30 mL/min), dose reduction may be necessary. Consult your doctor for individualized dosing. |
| Hepatic Impairment | In patients with mild to moderate hepatic impairment, no dose adjustment is required. In severe hepatic impairment, this medicine is contraindicated. Consult your doctor for alternative therapy. |
| Maximum Daily Dose | The maximum recommended daily dose is one capsule (Rabeprazole 20 mg + Itopride 150 mg) per day. Do not exceed this dose unless directed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of anurab it 20mg/150mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Ketoconazole | Major | |
| Atazanavir | Major | |
| Clopidogrel | Moderate | |
| Diazepam | Moderate | |
| Phenytoin | Moderate | |
| Anticholinergics | Moderate | |
| Antacids | Minor | |
| Sucralfate | Minor | |
| Digoxin | Minor |
🚨 Major Interactions
- Warfarin
- Ketoconazole, Itraconazole
- Atazanavir, Nelfinavir
- Methotrexate
⚡ Moderate Interactions
- Clopidogrel
- Diazepam
- Phenytoin
- Anticholinergic drugs
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Alcohol can increase stomach acid production, irritate the gastric mucosa, and worsen conditions like GERD and gastritis. It may also enhance the central nervous system effects of Itopride, such as dizziness or drowsiness. Additionally, alcohol can affect liver enzymes involved in drug metabolism, potentially altering the levels of Rabeprazole and Itopride in the body.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity or allergy to Rabeprazole, Itopride, or any component of the formulation","Severe hepatic impairment","Severe renal impairment","Gastrointestinal obstruction, perforation, or bleeding","Patients with a history of extrapyramidal symptoms","Concurrent use with atazanavir or nelfinavir"]
⚠️ Warnings & Precautions
["Use with caution in patients with liver disease; dose adjustment may be needed.","Use with caution in patients with kidney disease; monitor renal function.","May increase the risk of bone fractures with long-term use; ensure adequate calcium and vitamin D intake.","May cause low magnesium levels; monitor magnesium levels during prolonged therapy.","May increase the risk of Clostridium difficile-associated diarrhea; use antibiotics judiciously.","Itopride may cause extrapyramidal symptoms; discontinue if these occur.","Avoid use in patients with gastrointestinal obstruction or perforation.","Not recommended for children unless prescribed by a pediatrician.","Elderly patients may be more sensitive to the side effects, especially extrapyramidal symptoms.","Do not use for immediate relief of occasional heartburn."]
🤱 Lactation Safety
It is not known whether Rabeprazole and Itopride are excreted in human breast milk. Animal studies have shown excretion of Rabeprazole in breast milk. Because many drugs are excreted in human milk, caution should be exercised when this medicine is administered to a nursing woman. Consult your doctor to decide whether to discontinue nursing or discontinue the medicine, taking into account the importance of the drug to the mother.
💊 Overdose Management
Overdose of this medicine may cause symptoms such as drowsiness, confusion, nausea, vomiting, and abdominal pain. In case of suspected overdose, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if the patient presents within 1-2 hours of ingestion. Monitor vital signs and provide supportive care. Contact a poison control center for guidance.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Swallow the capsule whole with a glass of water; do not crush or chew it. It is best taken on an empty stomach, at least 30 minutes before breakfast, unless your doctor advises otherwise. Do not increase or decrease the dose without consulting your doctor. Avoid alcohol while taking this medicine, as it can worsen stomach irritation and reduce the effectiveness of treatment. Inform your doctor if you have liver or kidney problems, or if you are taking blood thinners, antifungals, or certain HIV medications. Do not use this medicine for longer than recommended without medical review. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before use. Keep this medicine out of reach of children and store it in a cool, dry place away from direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially extrapyramidal symptoms from Itopride. Dose adjustment may be needed based on renal and hepatic function. Regular monitoring is advised.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. It is classified as Pregnancy Category C, and its safety in pregnancy is not well-established. Your doctor may consider alternative treatments.
🏥 Post-Surgery Considerations
If you have recently undergone surgery, inform your surgeon and anesthesiologist about this medicine. It may affect gastric motility and acid secretion, which could influence postoperative care. Do not resume without medical advice.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. It may interact with certain medications used during dental work, and your dentist may need to adjust your treatment plan.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe while taking this medicine. However, avoid vigorous exercise immediately after meals, as it may worsen reflux. If you experience dizziness or fatigue, avoid strenuous activities until you feel better.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. If affected, avoid driving or operating heavy machinery. Otherwise, it should not significantly impact your daily work or routine. Take it as prescribed to manage symptoms effectively.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your symptoms resolve, your doctor may advise tapering or stopping. Abrupt discontinuation can lead to rebound acid hypersecretion.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to reduced magnesium and vitamin B12 levels, increased risk of bone fractures, and a slightly elevated risk of gastrointestinal infections. Periodic monitoring of magnesium, vitamin B12, and bone health may be advised. It is important to review the need for continued therapy with your doctor regularly.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Avoiding trigger foods like spicy, fatty, and acidic foods can reduce symptoms.
Evidence: Well-establishedLosing excess weight reduces abdominal pressure and reflux.
Evidence: Well-establishedYoga, meditation, and relaxation techniques can help reduce stress-related acid production.
Evidence: ModerateSome herbs like ginger and chamomile may soothe the stomach, but evidence is limited.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for any vaccination, inform your healthcare provider about all medicines you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If crossing time zones, continue taking it at the same time each day as close as possible to your usual schedule. For long trips, pack enough supply. Check customs regulations for carrying prescription medicines. Do not stop the medicine abruptly without consulting your doctor.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Rabeprazole starts reducing acid within 1 hour, but noticeable symptom relief may take 1 to 2 days. Itopride's prokinetic effects begin within 30 to 60 minutes. Full benefits may take 1 to 2 weeks.
A: It is best taken on an empty stomach, at least 30 minutes before breakfast. Food may delay the absorption of Rabeprazole.
A: Common side effects include headache, diarrhea, abdominal pain, nausea, and dry mouth. These are usually mild and temporary.
A: It is classified as Pregnancy Category C. Use only if clearly needed and after consulting your doctor.
A: Do not stop without consulting your doctor. Abrupt discontinuation may cause rebound acid hypersecretion.
🤔 Common Patient Concerns
🔄 Substitutes for anurab it 20mg/150mg tablet
View AllAlternative brands with exact same active ingredient:
-
stayhappi rabeprazole+itopride 20mg/150mg capsuleSarvagunaushdhi Pvt Ltd ₹30.00 74.4% CHEAPER
-
rabepride 20mg/150mg tabletKinesis Pharmaceuticals Pvt Ltd ₹48.75 58.4% CHEAPER
-
razo ir 20mg/150mg tabletDr Reddy's Laboratories Ltd ₹70.31 40% CHEAPER
-
Rezole-IT 20mg/150mg CapsuleRitz Pharma ₹70.31 40% CHEAPER
-
koserab it 20mg/150mg capsule srKosmed Formulations ₹74.00 36.9% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken for immediate heartburn relief.
Fact: This medicine is not for immediate relief. It is used for chronic acid-related conditions and takes time to work. - Myth: It is safe to take indefinitely without monitoring.
Fact: Long-term use requires monitoring for magnesium, vitamin B12, and bone health. - Myth: It can be taken with any other medicine without interaction.
Fact: It interacts with several drugs like warfarin, ketoconazole, and clopidogrel. Always inform your doctor about all medicines you take.
🔄 Alternative Options
Generic Alternatives
- Rabeprazole 20 mg + Itopride 150 mg capsule (generic versions available)
Brand Alternatives
- Aciflux 20 mg/150 mg capsule