antof plus tablet
What is antof plus tablet used for?
Antof Plus Tablet (Lactobacillus + Ofloxacin) is used to treat GASTRO INTESTINAL. It contains Lactobacillus (120Million spores) + Ofloxacin (200mg), which Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA rep. Always consult your doctor before use. Take as prescribed.
- Generic Name: Lactobacillus + Ofloxacin
- Manufacturer: Progressive Life Care
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ antof plus tablet Uses & Benefits
Infectious diarrhea, gastrointestinal infections, bacterial enteritis, prophylaxis of traveler's diarrhea.
Off-label uses: Not commonly used off-label.
๐ Drug Information
| Generic Name(s) | Lactobacillus + Ofloxacin |
| Brand Name | Antof Plus Tablet |
| Manufacturer | Progressive Life Care |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Antibiotic + Probiotic |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication; Lactobacillus restores gut flora.
Mechanism Steps
๐ก How to Take antof plus tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of antof plus tablet
โ Common Side Effects
- Nausea
- Diarrhea
- Headache
- Dizziness
- Insomnia
- Abdominal pain
๐จ Serious Side Effects
- Tendon rupture
- Peripheral neuropathy
- CNS effects (seizures, confusion)
- QT prolongation
- Clostridium difficile colitis
- Severe allergic reactions
โ ๏ธ Rare Side Effects
- Hepatotoxicity
- Nephrotoxicity
- Blood dyscrasias
- Photosensitivity
- Tendinitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Antacids (Mg/Al) | Major | Reduced ofloxacin absorption |
| Sucralfate | Major | Reduced ofloxacin absorption |
| Iron supplements | Major | Reduced ofloxacin absorption |
| Zinc supplements | Major | Reduced ofloxacin absorption |
| NSAIDs | Moderate | Increased CNS stimulation risk |
| Corticosteroids | Moderate | Increased tendon rupture risk |
| Cyclosporine | Moderate | Increased nephrotoxicity |
| Theophylline | Moderate | Increased theophylline levels |
| Caffeine | Moderate | Increased caffeine levels |
| Calcium supplements | Minor | Slightly reduced absorption |
| Multivitamins | Minor | Slightly reduced absorption |
๐จ Major Interactions
- Warfarin
- Antacids containing Mg/Al
- Sucralfate
- Iron supplements
- Zinc supplements
โก Moderate Interactions
- NSAIDs
- Corticosteroids
- Cyclosporine
- Theophylline
- Caffeine
โน๏ธ Minor Interactions
- Calcium supplements
- Multivitamins
๐ฝ๏ธ Food Interactions
Dairy products may reduce absorption; avoid with high calcium foods.
๐ท Alcohol Interaction
May increase CNS effects; avoid.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to fluoroquinolones, history of tendon disorders, epilepsy, children <18 years (except specific indications), pregnancy (relative).
๐ Monitoring Parameters
Renal function, liver enzymes, blood glucose, signs of tendonitis, CNS effects.
๐คฑ Lactation Safety
Ofloxacin excreted in milk; use caution. Lactobacillus safe.
๐ Overdose Management
Supportive care; gastric lavage if recent; monitor ECG, renal function.
โฐ Missed Dose
Take as soon as remembered unless near next dose; skip if close.
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Found this to be a helpful product. Good results.
Good quality medicine. Satisfied with the outcome.
Good quality medicine. Satisfied with the outcome.
Good quality medicine. Satisfied with the outcome.
Helpful and effective medicine as per my experience. Always consult a doctor.