antiuric 80mg tablet - Febuxostat (80mg) medicine

antiuric 80mg tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Pharmed Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
โš ๏ธ Hepatotoxicity Risk ๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is antiuric 80mg tablet used for?

Aluxo (Febuxostat) is used to treat PAIN ANALGESICS. It contains Febuxostat (80mg), which Selective inhibition of xanthine oxidase, reducing uric acid production.. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Febuxostat
  • Manufacturer: Pharmed Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š antiuric 80mg tablet Uses & Benefits

Chronic management of hyperuricemia in gout; prevention of gout flares.

Off-label uses: Prevention of tumor lysis syndrome, chronic kidney disease with hyperuricemia.

๐Ÿ“‹ Drug Information

Generic Name(s)Febuxostat
Brand NameAluxo
ManufacturerPharmed Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassXanthine oxidase Inhibitors-gout
Route of AdministrationOral.
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration; peak plasma concentration achieved in 1-1.5 hours.
DistributionWidely distributed; volume of distribution approximately 50 L.
Protein BindingApproximately 99% bound to plasma proteins, mainly albumin.
MetabolismExtensively metabolized in the liver via conjugation and oxidation (CYP1A2, CYP2C8, CYP2C9, and UGT1A1, UGT1A3, UGT1A9, UGT2B7).
Half-LifeApproximately 5-8 hours.
ExcretionExcreted in urine (49% as metabolites, 3% as unchanged drug) and feces (45% as metabolites).
BioavailabilityApproximately 84%.
Onset of ActionWithin 2 weeks of therapy.
Peak Plasma Time1-1.5 hours.
Duration of Action24 hours (once-daily dosing).

How It Works

Selective inhibition of xanthine oxidase, reducing uric acid production.

Mechanism Steps

1Febuxostat binds to the molybdenum-pterin active site of xanthine oxidase.
2Inhibits both oxidized and reduced forms of xanthine oxidase.
3Blocks conversion of hypoxanthine to xanthine and xanthine to uric acid.

๐Ÿ’ก How to Take antiuric 80mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of antiuric 80mg tablet

โœ… Common Side Effects

  • Nausea
  • Diarrhea
  • Headache
  • Joint pain
  • Liver enzyme elevation

๐Ÿšจ Serious Side Effects

  • Cardiovascular events
  • Severe skin reactions (e.g., Stevens-Johnson syndrome)
  • Hepatotoxicity

โš ๏ธ Rare Side Effects

  • Rhabdomyolysis
  • Interstitial nephritis
  • Anaphylaxis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Azathioprine Major Increased myelosuppression risk
Mercaptopurine Major Increased myelosuppression risk
Theophylline Major Increased theophylline toxicity
Warfarin Moderate Increased INR and bleeding risk
Thiazide diuretics Moderate Increased serum uric acid levels
ACE inhibitors Moderate Increased risk of angioedema
Antacids Minor Possible decreased absorption of febuxostat
Colchicine Minor No significant interaction

๐Ÿšจ Major Interactions

  • Azathioprine
  • Mercaptopurine
  • Theophylline

โšก Moderate Interactions

  • Warfarin
  • Thiazide diuretics
  • ACE inhibitors

โ„น๏ธ Minor Interactions

  • Antacids
  • Colchicine

๐Ÿฝ๏ธ Food Interactions

No significant food interactions; can be taken with or without food.

๐Ÿท Alcohol Interaction

Alcohol may increase uric acid levels; avoid excessive alcohol consumption.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to febuxostat, concomitant use with azathioprine or mercaptopurine.

๐Ÿ“Š Monitoring Parameters

Serum uric acid levels, liver function tests, renal function, signs of gout flares.

๐Ÿคฑ Lactation Safety

Not recommended; excreted in animal milk, unknown in humans.

๐Ÿ’Š Overdose Management

Symptomatic and supportive care; no specific antidote.

โฐ Missed Dose

Take as soon as remembered; if close to next dose, skip missed dose. Do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for antiuric 80mg tablet

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Alternative brands with exact same active ingredient (Febuxostat (80mg)):

Medical Note: Always consult your doctor before switching medications.

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