anticold ace syrup - Chlorpheniramine Maleate (2mg) + Phenylephrine (5mg) medicine

Ace Cold 2mg/5mg Tablet: Complete Medicine Guide

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🏭 Novo Medi Sciences Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 21, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for symptomatic relief of cold and allergy symptoms.
Reviewed by
SaathiMed Expert Panel | Oct 21, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Chest pain or irregular heartbeat
  • Severe headache with blurred vision
  • Difficulty breathing or swelling of face, lips, or throat
  • Severe dizziness or fainting
  • Difficulty urinating or no urine output
  • Yellowing of skin or eyes
  • Seizures or convulsions

If experiencing severe symptoms, call emergency services immediately.

What is anticold ace syrup used for?

This medicine is a combination of chlorpheniramine maleate 2 mg and phenylephrine 5 mg used for temporary relief of nasal congestion, runny nose, sneezing, and watery eyes due to cold or allergies. It works by blocking histamine and narrowing nasal blood vessels. It may cause drowsiness, so avoid driving. Do not use for more than 7 days without consulting a doctor.

  • Generic Name: Chlorpheniramine Maleate + Phenylephrine
  • Manufacturer: Novo Medi Sciences Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 anticold ace syrup के बारे में (Hindi Summary)

उपयोग: यह दवा क्लोरफेनिरामाइन मेलिएट 2 मिलीग्राम और फेनिलएफ्रिन 5 मिलीग्राम का संयोजन है। इसका उपयोग सर्दी, एलर्जी, नाक बहना, छींक आना, नाक बंद होना और आंखों में पानी आना जैसे लक्षणों से राहत पाने के लिए किया जाता है। यह दवा एलर्जी के कारण होने वाले लक्षणों को कम करने में मदद करती है। इसे डॉक्टर की सलाह के अनुसार ही लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, मुंह सूखना, चक्कर आना, सिरदर्द, जी मिचलाना और बेचैनी शामिल हैं। कुछ लोगों में दिल की धड़कन तेज हो सकती है या रक्तचाप बढ़ सकता है। यदि आपको गंभीर समस्या हो जैसे सीने में दर्द, सांस लेने में कठिनाई, या गंभीर सिरदर्द, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को बताएं यदि आपको उच्च रक्तचाप, हृदय रोग, मधुमेह, थायरॉइड, ग्लूकोमा, प्रोस्टेट की समस्या या पेशाब में कठिनाई है। इस दवा के साथ शराब न लें क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। गाड़ी चलाने या मशीन चलाने से बचें यदि आपको नींद आती है। बिना डॉक्टर की सलाह के 7 दिनों से अधिक इसका उपयोग न करें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 anticold ace syrup Uses & Benefits

[{"condition":"Common cold with nasal congestion","description":"This medicine provides temporary relief of runny nose, sneezing, and nasal stuffiness associated with the common cold.","evidence":"Well-established"},{"condition":"Allergic rhinitis","description":"This medicine helps reduce sneezing, itching, and watery eyes caused by seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Upper respiratory allergy symptoms","description":"This medicine is used for short-term relief of allergy-related nasal and throat symptoms.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Sinusitis-related congestion","description":"Sometimes used off-label for short-term relief of congestion associated with sinusitis, but evidence is limited.","evidence":"Limited"},{"condition":"Eustachian tube dysfunction","description":"Occasionally used off-label to help relieve pressure in the ear, but evidence is not strong.","evidence":"Limited"}]

Primary treatment for: Common cold and allergic rhinitis

Also treats: Sinusitis, Eustachian tube dysfunction

📋 Drug Information

Generic Name(s)Chlorpheniramine Maleate + Phenylephrine
Brand NameAscoril Flu Syrup
ManufacturerNovo Medi Sciences Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassAntihistamine + Decongestant
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food or milk if it upsets your stomach.
2
Avoid driving or operating heavy machinery until you know how this medicine affects you.
3
Do not drink alcohol while taking this medicine as it can increase drowsiness.
4
Do not use this medicine for more than 7 days without consulting your doctor.
5
If you have high blood pressure, heart disease, or diabetes, consult your doctor before taking this medicine.
6
Keep this medicine out of reach of children.
7
If you miss a dose, take it as soon as you remember, but do not double dose.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Runny nose
This medicine is commonly used for this symptom.
Likely Use
✅
Sneezing
This medicine helps reduce sneezing due to allergies or cold.
Likely Use
✅
Nasal congestion
This medicine contains a decongestant to relieve stuffy nose.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
❌
Body ache
This medicine is not intended for body aches.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionChlorpheniramine maleate is absorbed from the gastrointestinal tract after oral administration. Phenylephrine is also absorbed orally, but its bioavailability is limited due to first-pass metabolism in the gut and liver. Food does not significantly affect the absorption of chlorpheniramine, but it may delay the absorption of phenylephrine.
DistributionChlorpheniramine is widely distributed throughout the body, including the central nervous system, due to its lipophilic nature. Phenylephrine distributes into tissues but does not cross the blood-brain barrier significantly. Both drugs can cross the placenta and are excreted in breast milk.
Protein BindingChlorpheniramine is approximately 70% bound to plasma proteins. Protein binding data for phenylephrine is not well established from the available information.
MetabolismChlorpheniramine is metabolized in the liver, primarily by cytochrome P450 enzymes, including CYP2D6 and CYP3A4. Phenylephrine undergoes extensive first-pass metabolism in the gut and liver, mainly by monoamine oxidase and sulfotransferases.
Half-LifeThe elimination half-life of chlorpheniramine is approximately 12 to 43 hours in adults, with a longer half-life in the elderly. The elimination half-life of phenylephrine is approximately 2 to 3 hours.
ExcretionChlorpheniramine and its metabolites are excreted primarily in the urine. Phenylephrine and its metabolites are also excreted mainly in the urine, with a small amount excreted in feces.
BioavailabilityThe oral bioavailability of chlorpheniramine is approximately 25% to 50% due to first-pass metabolism. The oral bioavailability of phenylephrine is low, estimated to be less than 40%, due to extensive first-pass metabolism.
Onset of ActionThe onset of action for chlorpheniramine is typically within 30 to 60 minutes after oral administration. Phenylephrine has a more rapid onset, usually within 15 to 30 minutes, but its effect on nasal congestion may take longer to become noticeable.
Peak Plasma TimeThe peak plasma concentration of chlorpheniramine is reached approximately 2 to 6 hours after oral administration. For phenylephrine, peak plasma levels are reached within 1 to 2 hours.
Duration of ActionThe antihistamine effect of chlorpheniramine lasts approximately 4 to 6 hours, but drowsiness may persist longer. The decongestant effect of phenylephrine lasts about 4 to 6 hours. The duration of action may be prolonged in elderly patients or those with liver or kidney impairment.

How It Works

This medicine combines two active ingredients with different mechanisms. Chlorpheniramine maleate is a first-generation antihistamine that competitively blocks histamine H1 receptors on blood vessels and nerve endings, reducing sneezing, runny nose, and itching. Phenylephrine is an alpha-1 adrenergic receptor agonist that causes vasoconstriction of nasal blood vessels, which decreases swelling and congestion in the nasal passages. Together, these actions provide relief from both allergy symptoms and nasal stuffiness.

Mechanism Steps

1
Histamine H1 receptor blockade: Chlorpheniramine maleate binds to histamine H1 receptors, preventing histamine from triggering allergy symptoms such as sneezing and runny nose.
2
Alpha-1 adrenergic receptor activation: Phenylephrine stimulates alpha-1 adrenergic receptors on nasal blood vessels, causing them to constrict.
3
Reduced nasal swelling: The constriction of nasal blood vessels reduces blood flow and swelling in the nasal passages, which helps to open the airway and relieve congestion.
4
Central nervous system effects: Chlorpheniramine crosses the blood-brain barrier and causes drowsiness by blocking histamine in the brain.

💡 How to Take anticold ace syrup

Strength: Each tablet contains chlorpheniramine maleate 2 mg and phenylephrine 5 mg.

1Take this medicine by mouth with a glass of water.
2You may take it with or without food. If it upsets your stomach, take it with food or milk.
3Swallow the tablet whole. Do not crush, chew, or break it.
4Take it exactly as prescribed by your doctor.
5Do not take more than the recommended dose.
6If symptoms persist for more than 7 days, stop and consult your doctor.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet taken orally every 4 to 6 hours as needed for symptoms, not to exceed 6 tablets in 24 hours. However, the exact dose and frequency must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function, and response to treatment. Do not exceed the recommended dose. This medicine is for short-term use only.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine, especially drowsiness, confusion, and urinary retention. A lower dose may be appropriate. The dose must be individualized by a qualified clinician based on renal and hepatic function and overall health status.
Renal ImpairmentDose adjustment may be needed in patients with renal impairment. Consult a doctor for individualized dosing.
Hepatic ImpairmentDose adjustment may be needed in patients with hepatic impairment. Consult a doctor for individualized dosing.
Maximum Daily DoseThe maximum daily dose for adults is 6 tablets in 24 hours. Do not exceed this dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases drowsiness and sedation.
Caffeine
Limit
May increase nervousness and restlessness.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of anticold ace syrup

✅ Common Side Effects

Drowsiness (Common (more than 10%))
Avoid driving or operating machinery until you know how this medicine affects you. If drowsiness is severe, consult your doctor.
Dry mouth, nose, or throat (Common (5-10%))
Sip water frequently or chew sugar-free gum. Consult your doctor if it becomes bothersome.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying positions. Avoid sudden movements. Consult your doctor if dizziness persists.
Headache (Common (5-10%))
Rest and stay hydrated. If headache is severe or persistent, consult your doctor.
Nausea (Common (5-10%))
Take the medicine with food or milk to reduce stomach upset. Consult your doctor if nausea continues.
Nervousness or restlessness (Uncommon (1-5%))
Try to relax and avoid caffeine. If symptoms are bothersome, consult your doctor.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (less than 0.1%))
Seek emergency medical help immediately if you experience rash, itching, swelling of the face, lips, tongue, or throat, or difficulty breathing.
Irregular heartbeat or palpitations (Rare (less than 0.1%))
Stop the medicine and seek immediate medical attention if you feel a fast, pounding, or irregular heartbeat.
Severe high blood pressure (Rare (less than 0.1%))
Seek immediate medical attention if you experience severe headache, blurred vision, chest pain, or shortness of breath.
Difficulty urinating (Rare (less than 0.1%))
Consult your doctor if you are unable to urinate or have severe pain in the lower abdomen.
Seizures (Very rare (less than 0.01%))
Seek emergency medical help immediately if you experience convulsions or loss of consciousness.

⚠️ Rare Side Effects

Blood disorders such as hemolytic anemia or thrombocytopenia
Consult your doctor if you notice unusual bruising, bleeding, or fatigue.
Liver enzyme elevation
Report yellowing of skin or eyes, dark urine, or severe abdominal pain to your doctor immediately.
Hallucinations or confusion
Seek medical attention if you experience hallucinations, confusion, or unusual behavior.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAOIs Major
Tricyclic antidepressants Major
Beta-blockers Major
CNS depressants Moderate
Anticholinergics Moderate
Digoxin Moderate
Caffeine Minor
Antacids Minor

🚨 Major Interactions

  • Monoamine oxidase inhibitors (MAOIs)
  • Tricyclic antidepressants
  • Beta-blockers

⚡ Moderate Interactions

  • Central nervous system depressants (e.g., alcohol, benzodiazepines, opioids)
  • Anticholinergic drugs (e.g., atropine, benztropine)
  • Digoxin

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine because it can increase drowsiness, dizziness, and sedation caused by chlorpheniramine. Combining alcohol with this medicine can also impair your ability to drive or operate machinery. If you consume alcohol regularly, discuss it with your doctor before taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to chlorpheniramine, phenylephrine, or any component of the formulation","Severe hypertension or severe coronary artery disease","Use with monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping an MAOI","Narrow-angle glaucoma","Urinary retention or prostatic hypertrophy","Severe liver or kidney disease","Thyrotoxicosis"]

⚠️ Warnings & Precautions

["May cause drowsiness. Avoid driving or operating machinery until you know how this medicine affects you.","Do not use with alcohol or other central nervous system depressants.","Use with caution in patients with hypertension, heart disease, diabetes, thyroid disease, or glaucoma.","Do not use for longer than 7 days without consulting a doctor.","Keep out of reach of children.","Elderly patients are more sensitive to the side effects, especially drowsiness and confusion.","Do not take more than the recommended dose."]

🤱 Lactation Safety

Chlorpheniramine and phenylephrine may pass into breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the medicine, taking into account the importance of the medicine to the mother. Consult your doctor before use.

💊 Overdose Management

Overdose of this medicine may cause severe drowsiness, dizziness, confusion, rapid or irregular heartbeat, high blood pressure, seizures, or coma. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if the overdose is recent. Monitor vital signs and provide supportive care.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Before taking this medicine, tell your doctor if you have high blood pressure, heart disease, diabetes, thyroid problems, glaucoma, prostate enlargement, or difficulty urinating. Do not take this medicine with monoamine oxidase inhibitors or within 14 days of stopping them. Avoid alcohol and other sedatives because they can increase drowsiness. Do not take more than the recommended dose, and do not use it for longer than directed without consulting a doctor. If you are pregnant, planning to become pregnant, or breastfeeding, ask your doctor before using this medicine. Keep this medicine out of reach of children. Store it at room temperature away from moisture and heat. If symptoms do not improve within 7 days or if they worsen, stop the medicine and consult a doctor.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to the side effects of this medicine, especially drowsiness, confusion, dry mouth, and urinary retention. They may also be more prone to falls due to dizziness. Use with caution and consider a lower dose. Consult a doctor for individualized dosing.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant or are pregnant, consult your doctor before taking this medicine. The safety of this medicine during pregnancy has not been established. Your doctor will weigh the benefits and risks.

🏥 Post-Surgery Considerations

This medicine may interact with anesthetics and other medications used during surgery. Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be stopped before surgery. Consult your doctor for specific advice.

🦷 Dental Procedures

This medicine can cause dry mouth, which may increase the risk of dental problems. Inform your dentist that you are taking this medicine before any dental procedure. It may also interact with medications used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Stay hydrated by drinking plenty of fluids.
🥗
Get adequate rest to help your body recover.
😴
Use a humidifier to keep the air moist and ease nasal congestion.
💧
Avoid exposure to allergens such as dust, pollen, and pet dander.
🧘
Wash your hands frequently to prevent the spread of cold viruses.
🌞
Avoid smoking and secondhand smoke.

🏋️ Exercise Considerations

This medicine may cause drowsiness and dizziness. Avoid strenuous exercise or activities that require alertness until you know how the medicine affects you. If you exercise, do so with caution and stay hydrated.

🥗 Diet Recommendations

Drink warm fluids like soup and herbal tea to soothe your throat and loosen congestion.
Include vitamin C-rich foods such as oranges, lemons, and bell peppers.
Avoid alcohol and caffeine as they can worsen symptoms and interact with the medicine.
Eat light, easily digestible meals if you have a reduced appetite.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness, which may affect your ability to drive, operate machinery, or perform tasks that require mental alertness. It is best to avoid these activities until you know how the medicine affects you. If your work requires alertness, discuss with your doctor about alternative treatments.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects such as chest pain, severe headache, or difficulty breathing. Do not stop abruptly if you have been taking it for a long time without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended. Prolonged use of decongestants like phenylephrine can lead to rebound congestion. Long-term use of antihistamines like chlorpheniramine may cause tolerance and increased side effects such as drowsiness and dry mouth. If you need this medicine for more than 7 days, consult your doctor to evaluate the underlying condition.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Saline nasal spray

Helps moisturize nasal passages and relieve congestion without medication.

Evidence: Well-established
Steam inhalation

Can help loosen mucus and relieve nasal stuffiness.

Evidence: Limited
Antihistamine nasal sprays

Prescription nasal sprays like azelastine can relieve allergy symptoms with less sedation.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you are scheduled to receive a vaccine, inform your healthcare provider that you are taking this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If you are crossing time zones, continue taking it as needed for symptoms, but do not exceed the maximum daily dose. Check the customs regulations of your destination country regarding prescription medicines. If you are flying, keep it in your carry-on luggage. Avoid taking it before driving or operating machinery during travel.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with seasonal allergies
She started taking this medicine for her runny nose and sneezing. She noticed relief within an hour but felt very drowsy. She was advised to take it at bedtime and to avoid driving. She found that taking it with food reduced her stomach upset.
💡 Lesson: This medicine can cause significant drowsiness. It is best to take it when you do not need to be alert, and taking it with food can improve tolerability.
👤 A 50-year-old man with high blood pressure and a cold
He took this medicine for nasal congestion without consulting his doctor. He experienced a severe headache and his blood pressure was elevated. He was advised to stop the medicine and use a safer alternative for his cold.
💡 Lesson: People with high blood pressure should avoid this medicine unless specifically advised by a doctor, as phenylephrine can raise blood pressure.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30 to 60 minutes after taking it.

Q: Can I take it at night?

A: Yes, but it may cause drowsiness. It is often taken at bedtime to help with sleep while relieving symptoms.

Q: Is it safe for children?

A: Pediatric dosing is not established. Consult a pediatrician before giving this medicine to a child.

Q: Can I take it with other cold medicines?

A: Do not take it with other medicines containing similar ingredients without consulting your doctor, as it may lead to overdose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for anticold ace syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure the common cold.
    Fact: This medicine only relieves symptoms; it does not cure the underlying viral infection.
  • Myth: It is safe to take this medicine for weeks.
    Fact: This medicine should be used for short-term relief only, usually not more than 7 days without medical advice.
  • Myth: This medicine is safe for everyone.
    Fact: It is not safe for people with certain conditions like severe high blood pressure, heart disease, or glaucoma.

🔄 Alternative Options

Generic Alternatives

  • Chlorpheniramine maleate 2 mg + Phenylephrine 5 mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","active_ingredients":"Chlorpheniramine maleate 2 mg + Phenylephrine 5 mg","class":"First-generation antihistamine + decongestant","sedation":"High","duration":"4-6 hours"},{"medicine":"Cetirizine + Phenylephrine","active_ingredients":"Cetirizine 5 mg + Phenylephrine 10 mg","class":"Second-generation antihistamine + decongestant","sedation":"Low","duration":"12-24 hours"},{"medicine":"Loratadine + Pseudoephedrine","active_ingredients":"Loratadine 10 mg + Pseudoephedrine 240 mg","class":"Second-generation antihistamine + decongestant","sedation":"Low","duration":"24 hours"}]

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