ani spa 10mg/150mg tablet - Dicyclomine (10mg) + Ranitidine (150mg) medicine

ani spa 10mg/150mg tablet

4.3 (8 reviews)
๐Ÿญ Perk Pharmaceuticals Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 21, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 21, 2026

What is ani spa 10mg/150mg tablet used for?

Aciloc D 10 mg/150 mg Tablet (Dicyclomine + Ranitidine) is used to treat GASTRO INTESTINAL. It contains Dicyclomine (10mg) + Ranitidine (150mg), which Dicyclomine: Antimuscarinic, relaxes smooth muscle; Ranitidine: Competitive H2 r. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Dicyclomine + Ranitidine
  • Manufacturer: Perk Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š ani spa 10mg/150mg tablet Uses & Benefits

Irritable bowel syndrome, functional dyspepsia, peptic ulcer disease, gastroesophageal reflux disease

Off-label uses: Infant colic (dicyclomine), stress ulcer prophylaxis (ranitidine)

๐Ÿ“‹ Drug Information

Generic Name(s)Dicyclomine + Ranitidine
Brand NameAciloc D 10 mg/150 mg Tablet
ManufacturerPerk Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassAntispasmodic + H2 Receptor Antagonist
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light and moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionDicyclomine: Well absorbed orally; Ranitidine: Rapidly absorbed, peak plasma concentration 1-3 hours
DistributionDicyclomine: Widely distributed; Ranitidine: Widely distributed, crosses placenta
Protein BindingDicyclomine: ~90%; Ranitidine: ~15%
MetabolismDicyclomine: Hepatic; Ranitidine: Hepatic (N-oxide, S-oxide, desmethyl metabolites)
Half-LifeDicyclomine: 2-4 hours; Ranitidine: 2-3 hours
ExcretionDicyclomine: Urine (80% as metabolites); Ranitidine: Urine (30% unchanged, rest as metabolites)
BioavailabilityDicyclomine: ~50%; Ranitidine: ~50%
Onset of ActionDicyclomine: 1-2 hours; Ranitidine: 1 hour
Peak Plasma TimeDicyclomine: 1-2 hours; Ranitidine: 1-3 hours
Duration of ActionDicyclomine: 4-6 hours; Ranitidine: 8-12 hours

How It Works

Dicyclomine: Antimuscarinic, relaxes smooth muscle; Ranitidine: Competitive H2 receptor antagonist, reduces gastric acid secretion

Mechanism Steps

1Dicyclomine binds to muscarinic acetylcholine receptors in gastrointestinal smooth muscle
2Blocks the action of acetylcholine, reducing smooth muscle spasms and motility
3Ranitidine competitively blocks histamine H2 receptors on gastric parietal cells

๐Ÿ’ก How to Take ani spa 10mg/150mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of ani spa 10mg/150mg tablet

โœ… Common Side Effects

  • Dry mouth
  • Drowsiness
  • Dizziness
  • Constipation
  • Headache
  • Diarrhea

๐Ÿšจ Serious Side Effects

  • Arrhythmias
  • Confusion
  • Hallucinations
  • Hepatitis
  • Pancreatitis
  • Agranulocytosis

โš ๏ธ Rare Side Effects

  • Anaphylaxis
  • Interstitial nephritis
  • Gynecomastia
  • Impotence
  • Thrombocytopenia

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased INR and bleeding risk
Ketoconazole Major Reduced ketoconazole absorption
Atazanavir Major Reduced atazanavir absorption
Delavirdine Major Reduced delavirdine absorption
Antacids Moderate Reduced ranitidine absorption
Sucralfate Moderate Reduced ranitidine absorption
Probenecid Moderate Increased ranitidine levels
Triazolam Moderate Increased triazolam levels
Caffeine Minor Possible increased caffeine levels
Theophylline Minor Possible increased theophylline levels

๐Ÿšจ Major Interactions

  • Warfarin
  • Ketoconazole
  • Atazanavir
  • Delavirdine

โšก Moderate Interactions

  • Antacids
  • Sucralfate
  • Probenecid
  • Triazolam

โ„น๏ธ Minor Interactions

  • Caffeine
  • Theophylline

๐Ÿฝ๏ธ Food Interactions

High-fat meals may delay absorption, Antacids may reduce absorption

๐Ÿท Alcohol Interaction

Increased risk of gastric irritation; avoid alcohol

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity, glaucoma, obstructive uropathy, severe ulcerative colitis, myasthenia gravis

๐Ÿ“Š Monitoring Parameters

Renal function, hepatic function, ECG in elderly, anticholinergic effects

๐Ÿคฑ Lactation Safety

Caution; both drugs excreted in breast milk

๐Ÿ’Š Overdose Management

Symptomatic and supportive; gastric lavage, activated charcoal; physostigmine for anticholinergic symptoms

โฐ Missed Dose

Take as soon as remembered; skip if near next dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

๐Ÿ”— View Profile

โญ User Reviews

Verified User Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Certified Buyer Jul 10, 2026

Effective and reliable. Worked as expected.

Verified User Jul 10, 2026

Effective and reliable. Worked as expected.

Happy Patient Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Verified User Jul 10, 2026

Effective and reliable. Worked as expected.

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