ani spa 10mg/150mg tablet - Dicyclomine (10mg) + Ranitidine (150mg) medicine

Aciloc D 10 mg/150 mg Tablet: Complete Medicine Guide

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🏭 Perk Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 21, 2026
🤰 Pregnancy Category Not established from the available information. Consult your doctor if you are pregnant or planning to become pregnant. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate
Reviewed by
SaathiMed Expert Panel | Oct 21, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is ani spa 10mg/150mg tablet used for?

This medicine is a combination of dicyclomine and ranitidine used to treat abdominal cramps and excess stomach acid in conditions like irritable bowel syndrome and peptic ulcers. It works by relaxing stomach muscles and reducing acid production.

  • Generic Name: Dicyclomine + Ranitidine
  • Manufacturer: Perk Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 ani spa 10mg/150mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा पेट की ऐंठन, दर्द, एसिडिटी और गैस की समस्या में राहत देने के लिए इस्तेमाल की जाती है। यह इरिटेबल बाउल सिंड्रोम, पेट के अल्सर और गैस्ट्राइटिस जैसी स्थितियों में लाभकारी है। यह पेट की मांसपेशियों को आराम देकर ऐंठन कम करती है और पेट में एसिड का उत्पादन घटाती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में मुँह सूखना, चक्कर आना, नींद आना, धुंधली दृष्टि और कब्ज शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन तेज़ धड़कन, भ्रम, मतिभ्रम या गंभीर एलर्जी हो सकती है। ऐसा होने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक न बढ़ाएँ। दवा लेने के बाद नींद या धुंधली दृष्टि हो सकती है, इसलिए वाहन चलाने या मशीन चलाने से बचें। शराब न पिएँ। यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या आपको ग्लूकोमा, हृदय रोग, गुर्दे या यकृत की बीमारी है, तो डॉक्टर को बताएं। एंटासिड इस दवा से 2 घंटे पहले या बाद में न लें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 ani spa 10mg/150mg tablet Uses & Benefits

[{"condition":"Irritable bowel syndrome (IBS)","description":"Helps relieve abdominal cramps, spasms, and pain associated with IBS while reducing excess stomach acid.","evidence":"Well-established"},{"condition":"Peptic ulcer disease","description":"Reduces gastric acid secretion and relieves associated muscle spasms, aiding ulcer healing.","evidence":"Well-established"},{"condition":"Gastritis","description":"Provides relief from stomach inflammation and cramps by reducing acid and relaxing smooth muscles.","evidence":"Well-established"},{"condition":"Gastroesophageal reflux disease (GERD)","description":"May be used to reduce acid reflux symptoms and associated esophageal spasm.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Infantile colic","description":"Sometimes prescribed off-label for colic in infants, but safety and efficacy are not well established.","evidence":"Limited"},{"condition":"Biliary dyskinesia","description":"May be used off-label to relieve biliary tract spasms.","evidence":"Limited"}]

Primary treatment for: Irritable bowel syndrome

Also treats: Peptic ulcer disease, Gastritis, Gastroesophageal reflux disease

📋 Drug Information

Generic Name(s)Dicyclomine + Ranitidine
Brand NameAciloc D 10 mg/150 mg Tablet
ManufacturerPerk Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassAntispasmodic + H2 Receptor Antagonist
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with meals to reduce stomach upset.
2
Avoid driving or operating machinery until you know how it affects you.
3
Do not drink alcohol while taking this medicine.
4
Take antacids at least 2 hours before or after this medicine.
5
Report any fast heartbeat, confusion, or difficulty urinating immediately.
6
Do not stop taking this medicine without consulting your doctor.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Abdominal cramps
This medicine is commonly prescribed for this.
Likely Use
✅
Heartburn
Ranitidine component reduces acid.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionDicyclomine is well absorbed from the gastrointestinal tract. Ranitidine is rapidly absorbed after oral administration. Food does not significantly affect the absorption of either component.
DistributionDicyclomine is widely distributed in the body, including the central nervous system. Ranitidine distributes widely to body tissues and fluids, including breast milk.
Protein BindingDicyclomine is approximately 80% bound to plasma proteins. Ranitidine is about 15% bound to plasma proteins.
MetabolismDicyclomine is extensively metabolized in the liver. Ranitidine undergoes hepatic metabolism to a lesser extent, with about 30% metabolized in the liver.
Half-LifeDicyclomine: approximately 1.8 hours. Ranitidine: approximately 2.5 to 3 hours.
ExcretionDicyclomine is excreted mainly in urine and feces as metabolites. Ranitidine is primarily excreted unchanged in urine.
BioavailabilityDicyclomine: approximately 67% (oral). Ranitidine: approximately 50% (oral).
Onset of ActionDicyclomine: within 1 to 2 hours. Ranitidine: within 1 hour.
Peak Plasma TimeDicyclomine: 1 to 2 hours. Ranitidine: 1 to 3 hours.
Duration of ActionDicyclomine: 4 to 6 hours. Ranitidine: up to 12 hours.

How It Works

This medicine combines two active ingredients with complementary actions. Dicyclomine is an antimuscarinic agent that blocks acetylcholine at muscarinic receptors on smooth muscle, reducing spasms in the gastrointestinal tract. Ranitidine is a histamine H2-receptor antagonist that competitively blocks histamine at H2 receptors on gastric parietal cells, thereby reducing basal and stimulated gastric acid secretion. Together, they relieve abdominal cramps and reduce acid-related irritation.

Mechanism Steps

1
Dicyclomine blocks muscarinic receptors: Dicyclomine competitively inhibits acetylcholine binding at muscarinic receptors on gastrointestinal smooth muscle, preventing muscle contraction and thereby relieving spasms.
2
Ranitidine blocks H2 receptors: Ranitidine binds to histamine H2 receptors on gastric parietal cells, blocking histamine-stimulated acid secretion and reducing overall gastric acid output.
3
Combined effect: The antispasmodic action of dicyclomine and the acid-suppressing action of ranitidine work together to alleviate abdominal pain, cramps, and acid-related discomfort.

💡 How to Take ani spa 10mg/150mg tablet

Strength: Each tablet contains dicyclomine 10 mg and ranitidine 150 mg.

1Take this medicine orally with a full glass of water.
2Swallow the tablet whole; do not crush or chew.
3Take it with meals to reduce stomach upset.
4Follow your doctor's prescribed schedule exactly.
5Do not take antacids within 2 hours of this medicine.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally two to four times daily, as prescribed by your doctor. The exact dose and frequency depend on the condition being treated and your response to therapy. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the anticholinergic effects of dicyclomine. Use with caution and lower initial doses may be considered. Dose must be individualized by a qualified clinician.
Renal ImpairmentRanitidine dose should be reduced in patients with renal impairment. Dicyclomine should be used with caution. Consult your doctor for dose adjustment.
Hepatic ImpairmentDicyclomine is extensively metabolized in the liver; use with caution in hepatic impairment. Ranitidine dose may need adjustment. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is 4 tablets (dicyclomine 40 mg and ranitidine 600 mg). Do not exceed this without medical advice.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With meals
Take with food
Reduces stomach upset and improves tolerability.
Alcohol
Avoid
Increases drowsiness and stomach irritation.
Caffeine
Limit
May increase stomach acid and counteract ranitidine.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of ani spa 10mg/150mg tablet

✅ Common Side Effects

Dry mouth (Common (5-10%))
Sip water frequently or chew sugar-free gum. Consult doctor if persistent.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you.
Drowsiness (Common (5-10%))
Avoid alcohol and activities requiring alertness. Consult doctor if severe.
Blurred vision (Common (5-10%))
Usually temporary. Consult doctor if it persists or worsens.
Constipation (Common (5-10%))
Increase fiber and fluid intake. Consult doctor if no relief.

🚨 Serious Side Effects

Fast or irregular heartbeat (Rare (<0.1%))
Seek immediate medical attention.
Confusion or hallucinations (Rare (<0.1%))
Stop the medicine and contact your doctor immediately.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Call emergency services if you experience swelling of face, lips, or throat, or difficulty breathing.
Urinary retention (Rare (<0.1%))
Seek medical help if you are unable to urinate.

⚠️ Rare Side Effects

Hallucinations
Discontinue and seek immediate medical advice.
Agranulocytosis
Report any signs of infection (fever, sore throat) to your doctor promptly.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ketoconazole Major
Atazanavir Major
Warfarin Major
Antacids Moderate
Tricyclic antidepressants Moderate
Metformin Moderate
Paracetamol Minor
Ibuprofen Minor

🚨 Major Interactions

  • Ketoconazole
  • Atazanavir
  • Warfarin

⚡ Moderate Interactions

  • Antacids
  • Tricyclic antidepressants
  • Metformin

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine. It can increase drowsiness and dizziness caused by dicyclomine and may worsen stomach irritation by increasing acid production, counteracting the effect of ranitidine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to dicyclomine or ranitidine","Glaucoma (narrow-angle)","Myasthenia gravis","Urinary retention","Severe ulcerative colitis","Toxic megacolon","Breastfeeding"]

⚠️ Warnings & Precautions

["May cause drowsiness or blurred vision; avoid driving or operating machinery until effects are known.","Use with caution in elderly patients due to increased risk of confusion and anticholinergic effects.","Avoid in patients with obstructive uropathy or gastrointestinal obstruction.","Ranitidine may mask symptoms of gastric malignancy; ensure diagnosis is confirmed before starting therapy.","Do not exceed recommended dose; overdose may cause severe anticholinergic symptoms.","Consult doctor before use if you have kidney or liver disease, heart disease, or asthma."]

🤱 Lactation Safety

Dicyclomine and ranitidine are excreted in breast milk. Use with caution and only if clearly needed, as it may cause side effects in the nursing infant. Consult your doctor before breastfeeding.

💊 Overdose Management

Overdose may cause severe anticholinergic symptoms such as dry mouth, flushing, tachycardia, urinary retention, confusion, and hallucinations. Treatment is supportive and symptomatic. Gastric lavage may be considered if ingestion is recent. Physostigmine may be used cautiously for severe anticholinergic toxicity. Seek immediate medical attention.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it may cause drowsiness or blurred vision. Do not drink alcohol while taking this medicine, as it can increase drowsiness and stomach irritation. Inform your doctor if you have glaucoma, heart problems, kidney or liver disease, or difficulty urinating. Do not take antacids within two hours of this medicine, as they may reduce its absorption. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Keep all follow-up appointments and report any unusual symptoms promptly.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to anticholinergic side effects such as confusion, dry mouth, and urinary retention. Use with caution and lower doses may be needed. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. It is not recommended during pregnancy unless clearly needed. Discuss alternative treatments.

🏥 Post-Surgery Considerations

Consult your doctor before resuming this medicine after surgery, as it may affect gastric motility and acid secretion. It may interact with anesthetics and other post-operative medications.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may cause dry mouth and increase the risk of dental caries. It may also interact with certain anesthetics.

💚 Lifestyle Tips for Better Results

🏃
Eat small, frequent meals to reduce stomach acid.
🥗
Avoid spicy, fatty, and acidic foods.
😴
Maintain a healthy weight.
💧
Practice stress-reducing techniques like yoga or meditation.
🧘
Get adequate sleep.
🌞
Avoid smoking and alcohol.

🏋️ Exercise Considerations

Avoid strenuous exercise immediately after taking this medicine, as it may cause dizziness. Light activities like walking are generally safe. Stay hydrated.

🥗 Diet Recommendations

Include fiber-rich foods like fruits and vegetables.
Avoid caffeine and carbonated drinks.
Eat bland, easily digestible foods.
Stay well hydrated.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness or blurred vision, affecting your ability to drive or operate machinery. Avoid these activities until you know how it affects you. It may also cause dry mouth, which can be managed with frequent sips of water.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience severe side effects, contact your doctor immediately. Your doctor will advise on tapering or stopping based on your condition.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to tolerance, vitamin B12 deficiency (due to reduced acid), and increased risk of infections. Regular monitoring of kidney and liver function is advised. Do not use for prolonged periods without medical supervision.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Dietary changes

Avoiding trigger foods can reduce symptoms of IBS and acid reflux.

Evidence: Well-established
Stress management

Yoga, meditation, and counseling can help reduce stress-related stomach symptoms.

Evidence: Moderate
Probiotics

May help balance gut bacteria and improve digestive health.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established. However, long-term acid suppression may slightly reduce the efficacy of oral vaccines. Consult your doctor.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from light and moisture. If traveling across time zones, adjust dosing schedule gradually as advised by your doctor. Keep enough supply for the entire trip. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic abdominal cramps and acid reflux
Started this medicine as prescribed for irritable bowel syndrome. Within a week, noticed significant relief from cramps and heartburn. Emphasized taking it with food to prevent stomach upset and avoiding alcohol.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 60-year-old retiree with peptic ulcer disease
Was prescribed this medicine along with other ulcer medications. Reported reduced stomach pain and acidity after 10 days. Advised to avoid spicy foods and take antacids separately.
💡 Lesson: Combining medicine with dietary changes and proper timing of antacids enhances treatment success.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Dicyclomine starts working within 1-2 hours, while ranitidine reduces acid within 1 hour. Full effects may take a few days.

Q: Can I take it with other medicines?

A: Inform your doctor about all medicines you take, as this medicine can interact with several drugs including ketoconazole, atazanavir, and warfarin.

Q: Is it safe during pregnancy?

A: Consult your doctor. Safety is not well established; use only if clearly needed.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for ani spa 10mg/150mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure ulcers permanently.
    Fact: It helps manage symptoms but does not cure the underlying cause; complete treatment may require other medicines.
  • Myth: It is safe to take with alcohol.
    Fact: Alcohol increases drowsiness and stomach irritation; avoid it.
  • Myth: You can stop taking it once symptoms improve.
    Fact: Always complete the prescribed course and consult your doctor before stopping.

🔄 Alternative Options

Generic Alternatives

  • Dicyclomine 10 mg + Ranitidine 150 mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Dicyclomine 10 mg + Ranitidine 150 mg","onset":"1-2 hours","duration":"4-12 hours"},{"medicine":"Dicyclomine + Omeprazole","composition":"Dicyclomine 10 mg + Omeprazole 20 mg","onset":"1-2 hours","duration":"12-24 hours"},{"medicine":"Ranitidine alone","composition":"Ranitidine 150 mg","onset":"1 hour","duration":"12 hours"}]

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