angizaar at tablet - Uses, Price, Side Effects & Substitutes
What is angizaar at tablet used for?
Angizaar AT Tablet (Atenolol + Losartan) is used to treat CARDIAC. It contains Atenolol (50mg) + Losartan (50mg), which Atenolol: Selective beta-1 adrenergic receptor blocker reducing heart rate and c. Always consult your doctor before use. Take as prescribed.
- Generic Name: Atenolol + Losartan
- Manufacturer: Micro Labs Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ angizaar at tablet Uses & Benefits
Hypertension, chronic stable angina (atenolol), heart failure (losartan), diabetic nephropathy (losartan).
Off-label uses: Migraine prophylaxis (atenolol), Marfan syndrome (atenolol), heart failure with preserved EF (losartan).
๐ Drug Information
| Generic Name(s) | Atenolol + Losartan |
| Brand Name | Angizaar AT Tablet |
| Manufacturer | Micro Labs Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Antihypertensive (Beta-blocker + ARB) |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Atenolol: Selective beta-1 adrenergic receptor blocker reducing heart rate and contractility; Losartan: Angiotensin II receptor blocker (AT1) causing vasodilation and reduced aldosterone secretion.
Mechanism Steps
๐ก How to Take angizaar at tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of angizaar at tablet
โ Common Side Effects
- Fatigue
- Dizziness
- Bradycardia
- Hypotension
- Hyperkalemia
- Cough (less with losartan)
๐จ Serious Side Effects
- Heart block
- Bronchospasm
- Angioedema
- Renal failure
- Hepatotoxicity
โ ๏ธ Rare Side Effects
- Peyronie's disease (atenolol)
- Pancreatitis
- Thrombocytopenia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| NSAIDs | Major | Reduced antihypertensive effect, increased risk of renal impairment |
| Lithium | Major | Increased lithium toxicity |
| Potassium-sparing diuretics | Major | Hyperkalemia |
| Digoxin | Moderate | Bradycardia, heart block |
| Clonidine | Moderate | Rebound hypertension on withdrawal |
| Antacids | Minor | Reduced absorption of atenolol |
๐จ Major Interactions
- NSAIDs
- Lithium
- Potassium-sparing diuretics
- Other antihypertensives
โก Moderate Interactions
- Digoxin
- Clonidine
- CYP2C9 inhibitors (e.g., amiodarone)
- CYP3A4 inhibitors
โน๏ธ Minor Interactions
- Antacids
- Cimetidine
๐ฝ๏ธ Food Interactions
Avoid potassium-rich foods; Losartan absorption may be reduced by food.
๐ท Alcohol Interaction
Increased hypotensive effect; avoid excessive alcohol.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, severe bradycardia, heart block, cardiogenic shock, decompensated heart failure, pregnancy, bilateral renal artery stenosis.
๐ Monitoring Parameters
Blood pressure, heart rate, serum potassium, renal function, ECG.
๐คฑ Lactation Safety
Atenolol: Excreted in milk, caution; Losartan: Not recommended.
๐ Overdose Management
Supportive care: atropine for bradycardia, vasopressors for hypotension, hemodialysis for atenolol.
โฐ Missed Dose
Take as soon as remembered unless near next dose; skip if close to next dose.