angiplat 2.5 capsule tr

4.6 (9 reviews)

Nitroglycerin (2.5mg)

🏭 Micro Labs Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 21, 2026

🤰 Pregnancy Category C 📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 21, 2026

What is angiplat 2.5 capsule tr used for?

Angispan - TR 2.5mg Capsule (Nitroglycerin) is used to treat CARDIAC. It contains Nitroglycerin (2.5mg), which Nitroglycerin is converted to nitric oxide (NO) in smooth muscle cells, activati. Always consult your doctor before use. Take as prescribed.

Generic Name: Nitroglycerin
Manufacturer: Micro Labs Ltd
Form: Allopathy
Pregnancy Category: C
Prescription Required: Yes

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 angiplat 2.5 capsule tr Uses & Benefits

Prophylaxis of angina pectoris, long-term management of chronic stable angina.

Off-label uses: Heart failure (acute decompensated), hypertensive emergencies, anal fissures (topical).

📋 Drug Information

Generic Name(s)	Nitroglycerin
Brand Name	Angispan - TR 2.5mg Capsule
Manufacturer	Micro Labs Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	CARDIAC
Action Class	NO Donors
Route of Administration	Oral (sustained-release capsule).
Storage	Store at room temperature (20-25°C) in a tight, light-resistant container.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed from the gastrointestinal tract; undergoes extensive first-pass metabolism.

DistributionWidely distributed; volume of distribution approximately 3 L/kg.

Protein BindingApproximately 60% bound to plasma proteins.

MetabolismExtensively metabolized in the liver by glutathione-organic nitrate reductase and possibly by cytochrome P450 enzymes.

Half-Life1-4 minutes (parent drug); active metabolites have longer half-lives.

ExcretionRenal excretion of metabolites; less than 1% excreted unchanged.

BioavailabilityLow due to first-pass metabolism; sustained-release formulation improves bioavailability.

Onset of ActionWithin 30-60 minutes for sustained-release capsule.

Peak Plasma Time2-4 hours for sustained-release formulation.

Duration of ActionUp to 8-12 hours for sustained-release formulation.

How It Works

Nitroglycerin is converted to nitric oxide (NO) in smooth muscle cells, activating guanylate cyclase, increasing cGMP, leading to vasodilation.

Mechanism Steps

1Nitroglycerin is absorbed and undergoes denitration in smooth muscle cells.

2Releases nitric oxide (NO) via enzymatic and non-enzymatic pathways.

3NO activates soluble guanylate cyclase (sGC).

💡 How to Take angiplat 2.5 capsule tr

Follow your doctor's prescription exactly.

⚠️ Side Effects of angiplat 2.5 capsule tr

✅ Common Side Effects

Headache
Dizziness
Lightheadedness
Flushing
Orthostatic hypotension
Tachycardia

🚨 Serious Side Effects

Severe hypotension
Syncope
Methemoglobinemia (rare)
Paradoxical bradycardia

⚠️ Rare Side Effects

Allergic reactions
Exfoliative dermatitis
Angioedema

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Sildenafil	Major	Severe hypotension and syncope
Tadalafil	Major	Severe hypotension and syncope
Vardenafil	Major	Severe hypotension and syncope
Riociguat	Major	Severe hypotension
Alcohol	Moderate	Additive hypotension
Antihypertensives	Moderate	Increased hypotensive effect
Beta-blockers	Moderate	Enhanced antianginal effect, risk of bradycardia
Calcium channel blockers	Moderate	Additive hypotension and vasodilation
Aspirin	Moderate	Increased antiplatelet effect
Heparin	Minor	Possible decreased heparin effect
Acetylcysteine	Minor	Enhanced vasodilation

🚨 Major Interactions

Sildenafil
Tadalafil
Vardenafil
Riociguat

⚡ Moderate Interactions

Alcohol
Antihypertensives
Beta-blockers
Calcium channel blockers
Aspirin

ℹ️ Minor Interactions

Heparin
Acetylcysteine

🍽️ Food Interactions

High-fat meals may delay absorption.

🍷 Alcohol Interaction

Additive vasodilation and hypotension.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to nitrates, severe anemia, increased intracranial pressure, concurrent use with PDE-5 inhibitors or riociguat, constrictive pericarditis, pericardial tamponade, hypertrophic obstructive cardiomyopathy.

📊 Monitoring Parameters

Blood pressure, heart rate, relief of angina symptoms, tolerance development.

🤱 Lactation Safety

Unknown; caution advised.

💊 Overdose Management

Supportive care; elevate legs to improve venous return; administer fluids; if severe, use vasopressors (e.g., phenylephrine). Avoid epinephrine.

⏰ Missed Dose

Take as soon as remembered unless close to next dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

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🔄 Substitutes for angiplat 2.5 capsule tr

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Alternative brands with exact same active ingredient (Nitroglycerin (2.5mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

Regular Customer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Certified Buyer Jul 10, 2026

Found this to be a helpful product. Good results.