Angiplat 6.5 Capsule Tr (nitroglycerin): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Fainting or severe dizziness
- Chest pain that is more frequent, severe, or lasts longer than usual
- Bluish discoloration of lips, skin, or nails
- Shortness of breath or difficulty breathing
- Swelling of the face, lips, tongue, or throat
- Severe headache that does not go away
- Irregular or very slow heartbeat
- Sudden weakness or numbness on one side of the body
If experiencing severe symptoms, call emergency services immediately.
What is angiplat 6.5 capsule tr used for?
This medicine is an oral nitrate used to prevent angina chest pain in people with coronary artery disease. It works by relaxing blood vessels to improve blood flow to the heart and reduce its workload. It is not for immediate relief of an ongoing angina attack.
- Generic Name: Nitroglycerin
- Manufacturer: Micro Labs Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 angiplat 6.5 capsule tr के बारे में (Hindi Summary)
उपयोग: यह दवा नाइट्रोग्लिसरिन 6.5 मिलीग्राम कैप्सूल है, जिसका उपयोग एंजाइना (सीने में दर्द) को रोकने के लिए किया जाता है। यह रक्त वाहिकाओं को फैलाकर हृदय तक रक्त का प्रवाह बढ़ाती है और हृदय पर दबाव कम करती है। यह दवा तीव्र एंजाइना हमले के इलाज के लिए नहीं है, बल्कि इससे बचाव के लिए है। इसे डॉक्टर के निर्देशानुसार ही लें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, चक्कर आना, चेहरे पर लालिमा, और धड़कन तेज होना शामिल हैं। ये आमतौर पर शुरुआत में होते हैं और कुछ दिनों में ठीक हो जाते हैं। यदि आपको बेहोशी, सीने में तेज दर्द, या सांस लेने में कठिनाई हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे चबाएं या तोड़ें नहीं। शराब का सेवन न करें क्योंकि इससे रक्तचाप बहुत कम हो सकता है। सिल्डेनाफिल, टैडालाफिल जैसी दवाएं इस दवा के साथ बिल्कुल न लें। अचानक दवा बंद न करें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें।
💊 angiplat 6.5 capsule tr Uses & Benefits
[{"condition":"Chronic stable angina prophylaxis","description":"This medicine is used to prevent angina attacks in patients with coronary artery disease by reducing cardiac workload and improving coronary blood flow.","evidence":"Well-established"},{"condition":"Vasospastic angina","description":"It helps prevent chest pain caused by coronary artery spasm by relaxing the blood vessels.","evidence":"Well-established"},{"condition":"Heart failure with reduced ejection fraction","description":"In combination with other heart failure medicines, it may be used to reduce symptoms and improve exercise tolerance under specialist care.","evidence":"Moderate"},{"condition":"Esophageal spasm","description":"Nitroglycerin can relieve chest pain caused by esophageal spasm by relaxing smooth muscle.","evidence":"Limited"}]
Off-label uses: [{"condition":"Anal fissure","description":"Topical nitroglycerin is sometimes used off-label to relieve pain from anal fissures, but this oral form is not standard for that purpose.","evidence":"Limited"},{"condition":"Biliary colic","description":"Nitroglycerin may be used off-label to relax the sphincter of Oddi and relieve biliary colic pain in some settings.","evidence":"Limited"}]
Primary treatment for: Angina pectoris
Also treats: Coronary artery disease, Heart failure, Esophageal spasm
📋 Drug Information
| Generic Name(s) | Nitroglycerin |
| Brand Name | Angispan - TR 2.5mg Capsule |
| Manufacturer | Micro Labs Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | NO Donors |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep the capsules in their original container, tightly closed. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Nitroglycerin is a nitrate that is converted in the body to nitric oxide, which activates guanylate cyclase and increases cyclic guanosine monophosphate (cGMP). This leads to relaxation of vascular smooth muscle, resulting in vasodilation. The primary effect is on venous capacitance vessels, which reduces preload and cardiac workload. At higher doses, it also dilates coronary arteries and improves collateral blood flow to ischemic myocardium. This reduces myocardial oxygen demand and helps prevent angina.
Mechanism Steps
💡 How to Take angiplat 6.5 capsule tr
Strength: Immediate-release capsule containing 6.5 mg of Nitroglycerin.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one capsule (6.5 mg) taken orally once or twice daily, or as directed by your doctor. The dose may be adjusted based on your response and tolerance. This medicine is not for immediate relief of an acute angina attack. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and other medications you are taking. Do not change the dose without consulting your doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the blood pressure-lowering effects of this medicine. Start with a lower dose and monitor blood pressure closely. Dose must be individualized by a qualified clinician. |
| Renal Impairment | No specific dose adjustment is established for renal impairment. Use with caution and monitor blood pressure. Consult your doctor for individualized dosing. |
| Hepatic Impairment | No specific dose adjustment is established for hepatic impairment. Use with caution as metabolism may be altered. Consult your doctor for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is generally 13 mg (two 6.5 mg capsules) per day, but this may vary. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of angiplat 6.5 capsule tr
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Sildenafil | Major | |
| Tadalafil | Major | |
| Vardenafil | Major | |
| Riociguat | Major | |
| Alcohol | Major | |
| Beta-blockers | Moderate | |
| Calcium channel blockers | Moderate | |
| Tricyclic antidepressants | Moderate | |
| Ergotamine | Moderate | |
| Heparin | Minor |
🚨 Major Interactions
- Phosphodiesterase-5 inhibitors (sildenafil, tadalafil, vardenafil)
- Riociguat
- Alcohol
⚡ Moderate Interactions
- Antihypertensives (beta-blockers, calcium channel blockers, ACE inhibitors, ARBs, diuretics)
- Tricyclic antidepressants
- Ergot alkaloids (ergotamine, dihydroergotamine)
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it can intensify the blood pressure-lowering effect, leading to severe dizziness, fainting, and potentially dangerous hypotension. If you consume alcohol, discuss it with your doctor first.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to nitroglycerin or other nitrates","Concurrent use of phosphodiesterase-5 inhibitors (sildenafil, tadalafil, vardenafil)","Concurrent use of riociguat","Severe hypotension (systolic blood pressure
⚠️ Warnings & Precautions
["This medicine may cause severe hypotension, especially when standing up quickly. Rise slowly.","Tolerance to the effects can develop with continuous use. Follow your doctor's dosing schedule.","Avoid alcohol while taking this medicine.","Do not use erectile dysfunction drugs while on this medicine.","Use with caution in patients with liver or kidney disease.","Use with caution in the elderly due to increased risk of hypotension.","Do not abruptly stop this medicine without consulting your doctor, as it may worsen angina.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Keep out of reach of children."]
🤱 Lactation Safety
It is not known whether nitroglycerin is excreted in human breast milk. Because many drugs are excreted in human milk, caution should be exercised when this medicine is administered to a breastfeeding woman. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose of this medicine can cause severe hypotension, throbbing headache, confusion, fever, and methemoglobinemia. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and may include intravenous fluids, vasopressors for hypotension, and methylene blue for methemoglobinemia. Do not try to treat yourself at home.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor, usually once or twice daily with a glass of water. Do not crush, chew, or open the capsule unless your doctor instructs you to do so. To reduce the risk of dizziness, rise slowly from a sitting or lying position. Avoid alcohol while taking this medicine, as it can intensify the blood pressure-lowering effect and increase dizziness. Do not use erectile dysfunction medicines such as sildenafil, tadalafil, or vardenafil while on this medicine, as the combination can cause a life-threatening drop in blood pressure. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Keep this medicine out of reach of children. Store it at room temperature, away from moisture and direct sunlight. Do not stop taking this medicine suddenly without consulting your doctor, as this can worsen angina. Regular follow-up visits are important to monitor your blood pressure, heart rate, and overall response to treatment.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the blood pressure-lowering effects of this medicine and may experience more dizziness and falls. Start with a lower dose and monitor blood pressure closely. Ensure adequate hydration and rise slowly from sitting or lying positions.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before starting or continuing this medicine. It is classified as Pregnancy Category C, and the benefits must be weighed against potential risks. Your doctor may adjust your treatment plan.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. It may interact with anesthetic agents and affect blood pressure during surgery. Your doctor may advise you to stop it temporarily before surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It can cause dizziness or low blood pressure during dental work. Your dentist may take precautions such as monitoring your blood pressure.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise is beneficial for heart health, but you should avoid strenuous activities that trigger angina. Start slowly and gradually increase intensity. If you experience chest pain, dizziness, or shortness of breath during exercise, stop immediately and rest. Consult your doctor before starting any new exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or lightheadedness, especially when you first start taking it. Avoid driving or operating heavy machinery until you know how it affects you. If your job involves strenuous activity, discuss with your doctor about any necessary modifications. Most people can continue their normal activities with some precautions.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your condition changes, your doctor may adjust or stop the medicine. Abrupt withdrawal can cause rebound angina. Always follow your doctor's guidance.
📅 Long-Term Use Effects
Long-term use of this medicine can lead to tolerance, where the effect diminishes over time. To prevent tolerance, your doctor may prescribe a nitrate-free interval. Regular monitoring of blood pressure, heart rate, and angina frequency is important. Long-term use does not cause organ damage, but the underlying heart condition needs ongoing management. Periodic review with your doctor is essential.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and stress management can complement medicine for angina.
Evidence: Well-establishedBeta-blockers, calcium channel blockers, and other nitrates may be used.
Evidence: Well-establishedAngioplasty or bypass surgery may be considered for severe coronary artery disease.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, always inform your healthcare provider about all medicines you are taking before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid extreme temperatures in checked baggage. Store at room temperature and protect from light and moisture. If crossing time zones, consult your doctor about adjusting the dosing schedule. Carry enough supply for your entire trip. Check local customs regulations regarding prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 30 to 60 minutes after taking a dose, but it is not for immediate relief of an acute angina attack. It is used to prevent angina episodes.
A: Yes, you can take it with or without food. If it upsets your stomach, take it with a meal.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, do not stop suddenly as it can worsen angina. Consult your doctor before stopping.
A: It is classified as Pregnancy Category C. Consult your doctor if you are pregnant or planning to become pregnant.
🤔 Common Patient Concerns
🔄 Substitutes for angiplat 6.5 capsule tr
View AllAlternative brands with exact same active ingredient:
-
Nitract 6.5mg Capsule SRAstraZeneca ₹149.00 29.7% CHEAPER
-
angistat 6.5 capsule trSun Pharmaceutical Industries Ltd ₹155.00 26.8% CHEAPER
-
vasovin-xl 6.5 capsuleTorrent Pharmaceuticals Ltd ₹175.13 17.3% CHEAPER
-
Angispan-TR 6.5mg CapsuleUSV Ltd ₹285.19 34.7% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be used to treat an acute angina attack.
Fact: This medicine is for prevention of angina, not for immediate relief. Sublingual nitroglycerin is used for acute attacks. - Myth: It is safe to take erectile dysfunction drugs with this medicine.
Fact: Combining this medicine with erectile dysfunction drugs can cause a life-threatening drop in blood pressure and is contraindicated. - Myth: You can stop this medicine whenever you feel better.
Fact: Stopping suddenly can worsen angina. Always consult your doctor before stopping.
🔄 Alternative Options
Generic Alternatives
- Nitroglycerin 6.5 mg immediate-release capsule
Brand Alternatives
- Angiplat 6.5 capsule tr