anacort 100mg injection - Hydrocortisone (100mg) medicine

anacort 100mg injection

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Hydrocortisone (100mg)
🏭 Ancalima Lifesciences Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 21, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 21, 2026

What is anacort 100mg injection used for?

This medicine contains Hydrocortisone (100mg) and is used to treat RESPIRATORY. Binds to glucocorticoid receptors, leading to inhibition of phospholipase A2, reduced prostaglandin . Always consult your doctor before use.

  • Generic Name: Hydrocortisone
  • Manufacturer: Ancalima Lifesciences Ltd
  • Form: Allopathy
  • Pregnancy Category: Category C
  • Prescription Required: Yes
💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 anacort 100mg injection Uses & Benefits

Topical treatment of inflammatory and pruritic dermatoses such as eczema, dermatitis, psoriasis, and allergic reactions.

Off-label uses: Lichen planus, Lupus erythematosus, Alopecia areata

📋 Drug Information

Generic Name(s)Hydrocortisone
Brand NameAtonide-H Cream
ManufacturerAncalima Lifesciences Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassGlucocorticoids
Route of AdministrationTopical
StorageStore at 20-25°C (68-77°F); keep tube tightly closed; avoid freezing.
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionTopical absorption is minimal; systemic absorption may occur with prolonged use on large areas or occluded skin.
DistributionDistributes into tissues; crosses placenta and enters breast milk.
Protein BindingApproximately 90-95% bound to plasma proteins, primarily corticosteroid-binding globulin and albumin
MetabolismMetabolized primarily in the liver via reduction and conjugation.
Half-LifePlasma half-life: 1-2 hours; biological half-life: 8-12 hours.
ExcretionExcreted in urine as inactive metabolites; small amount excreted in feces.
BioavailabilitySystemic bioavailability is low (<1%) with topical application, but increases with occlusive dressin
Onset of ActionRapid; within hours for anti-inflammatory effect.
Peak Plasma TimeNot applicable for topical use; systemic levels peak within 1-2 hours after absorption.
Duration of ActionAnti-inflammatory effect lasts 8-12 hours after application.

How It Works

Binds to glucocorticoid receptors, leading to inhibition of phospholipase A2, reduced prostaglandin and leukotriene synthesis, and suppression of inflammatory cytokines.

Mechanism Steps

1Binds to glucocorticoid receptor in cytoplasm.
2Receptor-ligand complex translocates to nucleus.
3Binds to glucocorticoid response elements (GREs) on DNA.
4Modulates gene transcription: increases anti-inflammatory proteins (e.g., lipocortin-1) and decreases pro-inflammatory cytokines (e.g., IL-1, IL-2, TNF-alpha).
5Inhibits phospholipase A2, reducing arachidonic acid release and subsequent prostaglandin and leukotriene synthesis.
6Suppresses vasodilation, edema, and immune cell migration.

💡 How to Take anacort 100mg injection

Follow your doctor's prescription exactly.

⚠️ Side Effects of anacort 100mg injection

✅ Common Side Effects

Burning
itching
irritation
dryness
folliculitis
hypertrichosis
acneiform eruptions
hypopigmentation

🚨 Serious Side Effects

Allergic contact dermatitis
secondary infection
skin atrophy
striae
HPA axis suppression (with prolonged use)

⚠️ Rare Side Effects

Perioral dermatitis
maceration
miliaria
glaucoma (if applied near eyes)

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Rifampin Major Decreased corticosteroid efficacy due to increased metabolism.
Ketoconazole Major Increased corticosteroid exposure due to decreased metabolism.
Warfarin Moderate May alter anticoagulant effect; monitor INR.
Insulin Moderate May increase blood glucose; adjust insulin dose.

🚨 Major Interactions

  • CYP3A4 inducers (e.g., rifampin, phenytoin)
  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)

⚡ Moderate Interactions

  • Antidiabetic agents
  • Antihypertensives
  • Diuretics
  • NSAIDs

🍷 Alcohol Interaction

No known interaction with alcohol.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to hydrocortisone or any component; untreated bacterial, fungal, or viral skin infections; perioral dermatitis; rosacea.

🤱 Lactation Safety

Use with caution; minimal systemic absorption, but avoid application to breast area.

💊 Overdose Management

Acute overdose unlikely; chronic overuse may cause systemic effects. Discontinue use and treat symptomatically.

⏰ Missed Dose

Apply as soon as remembered; if near next dose, skip missed dose and resume regular schedule. Do not double dose.

🔄 Substitutes for anacort 100mg injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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