amzodox o 200mg/200mg tablet - Cefpodoxime Proxetil (200mg) + Ofloxacin (200mg) medicine

Acepod O 200mg/200mg Tablet: Complete Medicine Guide

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🏭 Amzor Healthcare 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 16, 2026
🤰 Pregnancy Category This medicine is not recommended during pregnancy unless clearly needed. Both cefpodoxime and ofloxacin may cross the placenta. Fluoroquinolones have been associated with cartilage damage in animal studies. Consult your doctor for alternative antibiotics. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 16, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of face, lips, or throat
  • Severe or bloody diarrhea
  • Tendon pain, swelling, or inability to move a joint
  • Numbness, tingling, or burning in hands or feet
  • Seizures or severe dizziness
  • Irregular heartbeat or palpitations
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is amzodox o 200mg/200mg tablet used for?

This medicine is a combination antibiotic containing Cefpodoxime Proxetil and Ofloxacin. It is used to treat various bacterial infections. It works by killing bacteria through two different mechanisms. It should be taken exactly as prescribed, usually every 12 hours with food.

  • Generic Name: Cefpodoxime Proxetil + Ofloxacin
  • Manufacturer: Amzor Healthcare
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 amzodox o 200mg/200mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा सेफपोडॉक्सिम प्रोक्सेटिल और ओफ्लोक्सासिन का संयोजन है, जिसका उपयोग विभिन्न जीवाणु संक्रमणों जैसे श्वसन तंत्र, मूत्र पथ, त्वचा और कोमल ऊतकों के संक्रमण के इलाज के लिए किया जाता है। यह दवा बैक्टीरिया को दो अलग-अलग तरीकों से मारती है, जिससे संक्रमण जल्दी ठीक होता है। इसे डॉक्टर के निर्देशानुसार ही लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, दस्त, पेट दर्द, सिरदर्द, चक्कर आना और त्वचा पर दाने शामिल हैं। गंभीर दुष्प्रभावों में एलर्जी, गंभीर दस्त, टेंडन टूटना, और दौरे पड़ना शामिल हो सकते हैं। यदि आपको कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक न छोड़ें और पूरा कोर्स पूरा करें। इसे भोजन के साथ लें ताकि पेट की परेशानी कम हो। एंटासिड, दूध या मिनरल सप्लीमेंट के साथ 2 घंटे का अंतराल रखें। शराब न पिएं। यदि आपको चक्कर आते हैं तो वाहन न चलाएं। गुर्दे या यकृत की समस्या हो तो डॉक्टर को बताएं।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 amzodox o 200mg/200mg tablet Uses & Benefits

[{"condition":"Community-acquired pneumonia","description":"Used to treat bacterial pneumonia caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Acute bacterial exacerbation of chronic bronchitis","description":"Helps in resolving bacterial infections in chronic bronchitis patients.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"Effective against uncomplicated and complicated UTIs caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Used for treating cellulitis, abscesses, and wound infections.","evidence":"Well-established"},{"condition":"Gonorrhea","description":"Ofloxacin component is effective against Neisseria gonorrhoeae.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Prostatitis","description":"Sometimes used off-label for chronic bacterial prostatitis.","evidence":"Limited"},{"condition":"Traveler's diarrhea","description":"May be used off-label for severe traveler's diarrhea.","evidence":"Limited"}]

Primary treatment for: Bacterial infections

Also treats: Respiratory tract infections, Urinary tract infections, Skin infections, Soft tissue infections

📋 Drug Information

Generic Name(s)Cefpodoxime Proxetil + Ofloxacin
Brand NameAcepod O 200mg/200mg Tablet
ManufacturerAmzor Healthcare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassCephalosporin + Fluoroquinolone
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Complete the full course even if you feel better after a few days.
3
Avoid taking antacids, dairy products, or mineral supplements within 2 hours of this medicine.
4
Drink plenty of water throughout the day to stay hydrated.
5
Avoid alcohol while taking this medicine as it may increase dizziness and drowsiness.
6
Do not drive or operate heavy machinery if you experience dizziness.
7
Report any tendon pain, numbness, or tingling to your doctor immediately.
8
Inform your doctor if you have kidney or liver problems before taking this medicine.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Fever with productive cough
This medicine is commonly prescribed for respiratory tract infections.
Likely Use
✅
Burning urination
This medicine is effective for urinary tract infections.
Likely Use
❌
Runny nose and sneezing
This medicine is not effective for viral infections like the common cold.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionCefpodoxime proxetil is absorbed from the gastrointestinal tract after oral administration and hydrolyzed to cefpodoxime. Ofloxacin is rapidly and almost completely absorbed orally. Food may slightly affect absorption but is generally not clinically significant.
DistributionCefpodoxime distributes widely into body tissues and fluids, including lungs, tonsils, and urine. Ofloxacin distributes extensively into tissues, including prostate, lungs, and skin. Both drugs cross the placenta and are excreted in breast milk.
Protein BindingCefpodoxime is approximately 20-30% bound to plasma proteins. Ofloxacin is approximately 20-30% bound to plasma proteins.
MetabolismCefpodoxime is minimally metabolized. Ofloxacin is minimally metabolized in the liver.
Half-LifeThe elimination half-life of cefpodoxime is approximately 2-3 hours. The elimination half-life of ofloxacin is approximately 4-5 hours.
ExcretionCefpodoxime is primarily excreted unchanged in the urine. Ofloxacin is primarily excreted unchanged in the urine.
BioavailabilityThe oral bioavailability of cefpodoxime proxetil is approximately 50%. The oral bioavailability of ofloxacin is approximately 95%.
Onset of ActionThe onset of action is typically within 1-2 hours after oral administration.
Peak Plasma TimePeak plasma concentrations of cefpodoxime are reached in about 2-3 hours. Peak plasma concentrations of ofloxacin are reached in about 1-2 hours.
Duration of ActionThe duration of action is approximately 12 hours for cefpodoxime and 12-24 hours for ofloxacin, depending on the dose and susceptibility of the organism.

How It Works

This medicine combines two antibiotics with distinct mechanisms. Cefpodoxime Proxetil, a prodrug, is hydrolyzed to cefpodoxime, which inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, leading to bacterial lysis. Ofloxacin inhibits DNA gyrase and topoisomerase IV, enzymes required for DNA replication, transcription, repair, and recombination, resulting in bacterial cell death.

Mechanism Steps

1
Cefpodoxime inhibits cell wall synthesis: Cefpodoxime binds to penicillin-binding proteins, blocking peptidoglycan cross-linking, weakening the bacterial cell wall.
2
Ofloxacin inhibits DNA replication: Ofloxacin binds to DNA gyrase and topoisomerase IV, preventing DNA supercoiling and replication, leading to bacterial death.
3
Combined bactericidal effect: The dual mechanism enhances bacterial killing and reduces the likelihood of resistance development.

💡 How to Take amzodox o 200mg/200mg tablet

Strength: Each immediate-release tablet contains Cefpodoxime Proxetil 200 mg and Ofloxacin 200 mg.

1Take the tablet with a full glass of water.
2Swallow the tablet whole; do not crush or chew.
3Take with food to reduce stomach upset.
4Avoid taking antacids, dairy, or mineral supplements within 2 hours.
5Take at evenly spaced intervals (every 12 hours).
6Complete the full course as prescribed.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet (Cefpodoxime 200 mg + Ofloxacin 200 mg) taken orally every 12 hours for 7 to 14 days, depending on the type and severity of infection. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require dose adjustment based on renal function. Use with caution due to increased risk of tendon rupture and CNS effects.
Renal ImpairmentDose adjustment is required in patients with renal impairment. For creatinine clearance less than 30 mL/min, the dose should be reduced or the interval extended. Consult a clinician for specific dosing.
Hepatic ImpairmentNo specific dose adjustment is established for hepatic impairment. Use with caution and monitor liver function.
Maximum Daily DoseThe maximum recommended daily dose is 400 mg of cefpodoxime and 400 mg of ofloxacin (two tablets per day).

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and improves absorption.
Dairy products
Separate by 2 hours
Calcium can bind to ofloxacin and reduce its absorption.
Antacids
Separate by 2 hours
Aluminum and magnesium can chelate with ofloxacin.

⏰ What to Do If You Miss a Dose

📌 Less than 6 hours since missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 6 hours since missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of amzodox o 200mg/200mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. Consult doctor if persistent.
Diarrhea (Common (5-10%))
Stay hydrated. Consult doctor if severe or bloody.
Headache (Common (5-10%))
Usually resolves. Consult doctor if severe.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you.
Rash (Common (1-5%))
Consult doctor if rash develops or worsens.

🚨 Serious Side Effects

Anaphylaxis (Rare (<0.1%))
Seek immediate medical attention if you experience difficulty breathing, swelling of face, lips, or throat.
Clostridioides difficile-associated diarrhea (Rare (<0.1%))
Seek medical attention if you develop severe, persistent diarrhea or bloody stools.
Tendon rupture (Rare (<0.1%))
Stop taking and seek immediate medical attention if you experience tendon pain, swelling, or inability to move a joint.
Peripheral neuropathy (Rare (<0.1%))
Report numbness, tingling, or burning sensation in hands or feet to your doctor.
Seizures (Rare (<0.1%))
Seek immediate medical attention if seizures occur.

⚠️ Rare Side Effects

Photosensitivity
Avoid prolonged sun exposure and use sunscreen.
QT interval prolongation
Inform doctor if you have palpitations or fainting.
Blood dyscrasias
Report unusual bruising or bleeding.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Antacids Major
Theophylline Major
NSAIDs Major
Corticosteroids Major
Probenecid Moderate
Oral hypoglycemics Moderate
Phenytoin Moderate
Caffeine Minor
Cyclosporine Minor

🚨 Major Interactions

  • Antacids, sucralfate, iron, zinc
  • Warfarin
  • Theophylline
  • NSAIDs
  • Corticosteroids

⚡ Moderate Interactions

  • Probenecid
  • Oral hypoglycemics
  • Phenytoin

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine as it may increase the risk of central nervous system side effects such as dizziness, drowsiness, and seizures. It may also worsen gastrointestinal irritation.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to cephalosporins or fluoroquinolones","History of tendon disorders with fluoroquinolones","Myasthenia gravis","Pregnancy and breastfeeding (unless clearly needed)","Children under 18 years (fluoroquinolones)","Severe renal impairment (dose adjustment required)"]

⚠️ Warnings & Precautions

["Serious allergic reactions including anaphylaxis can occur.","Clostridioides difficile-associated diarrhea may occur.","Tendon rupture risk increased in elderly, transplant patients, and those on corticosteroids.","Peripheral neuropathy may occur.","Central nervous system effects including seizures, dizziness, and confusion.","Photosensitivity reactions may occur; avoid sun exposure.","May exacerbate myasthenia gravis.","QT interval prolongation risk.","Do not use for viral infections.","Complete the full course to prevent resistance."]

🤱 Lactation Safety

This medicine is excreted in breast milk. It is not recommended during breastfeeding unless the potential benefit justifies the risk. Consult your doctor for alternatives.

💊 Overdose Management

Overdose may cause nausea, vomiting, diarrhea, and central nervous system effects. There is no specific antidote. Treatment is symptomatic and supportive. Maintain adequate hydration. Hemodialysis may be considered for ofloxacin overdose but is not effective for cefpodoxime. Contact a poison control center or emergency department immediately.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop treatment early, even if you feel better, as this can lead to antibiotic resistance. Take the tablet with a full glass of water, with or without food, but preferably with food to reduce stomach upset. Avoid taking antacids, multivitamins, or dairy products within 2 hours before or after taking this medicine, as they can reduce absorption. Avoid alcohol while taking this medicine. Inform your doctor if you have kidney or liver problems, diabetes, or a history of tendon disorders. Do not drive or operate heavy machinery if you experience dizziness. Complete the full course as prescribed. If you miss a dose, take it as soon as you remember, but if it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of tendon rupture, peripheral neuropathy, and CNS effects. Dose adjustment may be needed based on renal function. Monitor closely for any adverse effects.

🤰 Pregnancy Planning (TTC)

This medicine is not recommended during pregnancy or when planning pregnancy. Consult your doctor for safe alternatives if you are trying to conceive.

🏥 Post-Surgery Considerations

This medicine may be prescribed to prevent or treat surgical site infections. Inform your surgeon if you are taking this medicine before any surgery. It may interact with anesthetics and other medications.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure. It may interact with other medications used during dental work. Maintain good oral hygiene to prevent infection.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated by drinking plenty of water.
🥗
Get adequate rest to help your body fight the infection.
😴
Maintain good hygiene to prevent the spread of infection.
💧
Eat a balanced diet rich in fruits and vegetables.
🧘
Avoid alcohol and caffeine while taking this medicine.
🌞
Complete the full course even if you feel better.

🏋️ Exercise Considerations

Avoid strenuous exercise or heavy lifting while taking this medicine, as it may increase the risk of tendon rupture. If you experience joint pain or swelling, stop exercising and consult your doctor.

🥗 Diet Recommendations

Take the medicine with food to reduce stomach upset.
Avoid dairy products within 2 hours of taking the medicine.
Stay well hydrated.
Include probiotics like yogurt (but separate by 2 hours) to maintain gut health.
Avoid spicy and oily foods that may irritate the stomach.

💼 Impact on Daily Work & Life

This medicine may cause dizziness, drowsiness, or confusion. Avoid driving or operating heavy machinery until you know how it affects you. It is advisable to take rest and avoid strenuous activities during the course of treatment.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early can lead to recurrence of infection and antibiotic resistance. If you experience serious side effects, contact your doctor immediately; they may advise you to stop.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to antibiotic resistance, fungal overgrowth, and rare but serious effects such as tendon damage, peripheral neuropathy, and liver or kidney problems. Regular monitoring of renal and hepatic function is advised for prolonged therapy. Use only for the prescribed duration.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Probiotics

May help prevent antibiotic-associated diarrhea.

Evidence: Limited
Increased fluid intake

Helps flush out bacteria in urinary tract infections.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Antibiotics may reduce the effectiveness of live bacterial vaccines such as typhoid vaccine. Complete the antibiotic course before receiving live vaccines, or consult your doctor for timing.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from light and moisture. If traveling across time zones, adjust dosing times gradually to maintain even intervals. Check customs regulations for carrying prescription medicines. Keep a list of your medications with you at all times.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with a urinary tract infection
She was prescribed this medicine for a UTI. She took it with food twice daily and completed the 7-day course. Her symptoms improved within 3 days, and she felt completely better by the end of the course. She experienced mild nausea initially, which subsided after taking it with meals.
💡 Lesson: Taking the medicine with food helps reduce nausea and improves tolerability. Completing the full course prevents recurrence.
👤 A 60-year-old man with chronic bronchitis
He was given this medicine for an acute exacerbation of chronic bronchitis. He was advised to avoid antacids and dairy within 2 hours of the dose. He completed the 10-day course and his breathing improved significantly. He was monitored for tendon pain due to his age.
💡 Lesson: Elderly patients should be monitored for tendon-related side effects. Adhering to dietary restrictions ensures optimal absorption.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 2-3 days, but it is important to complete the full course as prescribed.

Q: Can I take this medicine with food?

A: Yes, take it with food to reduce stomach upset. Avoid dairy and antacids within 2 hours.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for amzodox o 200mg/200mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure viral infections like the flu.
    Fact: This medicine is an antibiotic and is only effective against bacterial infections. It does not treat viral infections.
  • Myth: You can stop taking this medicine once you feel better.
    Fact: You must complete the full course as prescribed to prevent the infection from returning and to avoid antibiotic resistance.
  • Myth: This medicine is safe to take without a prescription.
    Fact: This is a prescription medicine and should only be taken under the guidance of a qualified healthcare professional.

🔄 Alternative Options

Generic Alternatives

  • Cefpodoxime Proxetil + Ofloxacin generic tablets

Brand Alternatives

  • Acepod O 200mg/200mg Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Cefpodoxime + Ofloxacin","composition":"Cefpodoxime Proxetil 200mg + Ofloxacin 200mg","uses":"Respiratory, urinary, skin infections","notes":"Broad-spectrum combination"},{"medicine":"Cefixime + Ofloxacin","composition":"Cefixime 200mg + Ofloxacin 200mg","uses":"Similar indications","notes":"Alternative cephalosporin"}]

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