Amoxsyn CV 375 Tablet - Uses, Price, Side Effects
What is amoxsyn cv 375 tablet used for?
Amoxsyn CV 375 Tablet is a combination antibiotic containing Amoxycillin (250mg) and Clavulanic Acid (125mg). It is used to treat bacterial infections such as respiratory tract infections, urinary tract infections, and skin infections. Amoxycillin kills bacteria by inhibiting cell wall synthesis, while Clavulanic Acid prevents bacterial resistance by inhibiting beta-lactamase enzymes.
- Generic Name: Amoxicillin + Clavulanic Acid
- Manufacturer: Synmedic Laboratories
- Form: Allopathy
- Pregnancy Category: B
- Prescription Required: Yes
๐ amoxsyn cv 375 tablet Uses & Benefits
Respiratory tract infections, Urinary tract infections, Skin and soft tissue infections, Otitis media, Sinusitis, Bone and joint infections
Off-label uses: Prophylaxis in dental procedures (for endocarditis risk), Lyme disease (early localized)
๐ Drug Information
| Generic Name(s) | Amoxicillin + Clavulanic Acid |
| Brand Name | Amoxyclav 625 Tablet |
| Manufacturer | Synmedic Laboratories |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Penicillin Antibiotics |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC); protect from moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Amoxicillin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs); clavulanic acid is a beta-lactamase inhibitor that prevents inactivation of amoxicillin by resistant bacteria.
Mechanism Steps
๐ก How to Take amoxsyn cv 375 tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of amoxsyn cv 375 tablet
โ Common Side Effects
- Diarrhea
- Nausea
- Vomiting
- Rash
- Vaginal candidiasis
๐จ Serious Side Effects
- Anaphylaxis
- Stevens-Johnson syndrome
- Cholestatic jaundice
- Pseudomembranous colitis
- Seizures (high doses)
โ ๏ธ Rare Side Effects
- Agranulocytosis
- Hemolytic anemia
- Interstitial nephritis
- Hepatitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Methotrexate | Moderate | Increased methotrexate toxicity |
| Oral Contraceptives | Minor | Reduced contraceptive efficacy |
๐จ Major Interactions
- Methotrexate (increased toxicity)
- Warfarin (increased INR)
- Allopurinol (increased rash risk)
โก Moderate Interactions
- Oral contraceptives (reduced efficacy)
- Probenecid (increased amoxicillin levels)
- Mycophenolate (decreased levels)
โน๏ธ Minor Interactions
- Chloramphenicol (antagonism)
- Tetracyclines (antagonism)
๐ฝ๏ธ Food Interactions
No significant interaction; can be taken with or without food.
๐ท Alcohol Interaction
No direct interaction; but alcohol may reduce immune response.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to penicillins or beta-lactam antibiotics, History of cholestatic jaundice/hepatic dysfunction with amoxicillin-clavulanate, Infectious mononucleosis (risk of rash)
๐ Monitoring Parameters
Renal function, Hepatic function, CBC, Signs of hypersensitivity
๐คฑ Lactation Safety
Compatible; small amounts excreted in breast milk; monitor for diarrhea or rash in infant.
๐ Overdose Management
Supportive care; activated charcoal if recent ingestion; hemodialysis may help.
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose; do not double.