acirax cream - Uses, Price, Side Effects & Substitutes
What is acirax cream used for?
Acivir Cream (Acyclovir) is used to treat DERMA. It contains Acyclovir (5% w/w), which Inhibits viral DNA synthesis by competing with deoxyguanosine triphosphate for v. Always consult your doctor before use. Take as prescribed.
- Generic Name: Acyclovir
- Manufacturer: Synmedic Laboratories
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ acirax cream Uses & Benefits
Herpes simplex virus (HSV) infections: cold sores (herpes labialis), genital herpes; herpes zoster (shingles) - topical use for cutaneous lesions.
Off-label uses: Eczema herpeticum, Herpetic whitlow, Prevention of HSV recurrence in immunocompromised patients (topical)
๐ Drug Information
| Generic Name(s) | Acyclovir |
| Brand Name | Acivir Cream |
| Manufacturer | Synmedic Laboratories |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | Antiviral (Non-HIV) drugs |
| Route of Administration | Topical. |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits viral DNA synthesis by competing with deoxyguanosine triphosphate for viral DNA polymerase and incorporating into viral DNA, causing chain termination.
Mechanism Steps
๐ก How to Take acirax cream
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of acirax cream
โ Common Side Effects
- Burning or stinging at application site
- Dry skin
- Pruritus
- Erythema
๐จ Serious Side Effects
- Angioedema
- Stevens-Johnson syndrome (rare)
- Acute renal failure (systemic)
โ ๏ธ Rare Side Effects
- Contact dermatitis
- Urticaria
- Localized edema
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Probenecid | Major | Decreased renal clearance of acyclovir, increased toxicity risk. |
| Cimetidine | Major | Increased acyclovir AUC and half-life. |
| Mycophenolate mofetil | Major | Increased plasma concentrations of both drugs. |
| Interferon | Moderate | Synergistic antiviral effect; monitor for toxicity. |
| Zidovudine | Moderate | Increased risk of neurotoxicity. |
| Tacrolimus | Moderate | Increased nephrotoxicity risk. |
| Valproic acid | Minor | Possible decreased acyclovir efficacy. |
| Phenytoin | Minor | Decreased phenytoin levels reported. |
๐จ Major Interactions
- Probenecid
- Cimetidine
- Mycophenolate mofetil
โก Moderate Interactions
- Interferon
- Zidovudine
- Tacrolimus
โน๏ธ Minor Interactions
- Valproic acid
- Phenytoin
๐ฝ๏ธ Food Interactions
No significant food interactions.
๐ท Alcohol Interaction
No known interaction.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to acyclovir or valacyclovir.
๐ Monitoring Parameters
Lesion healing, pain relief; renal function if prolonged systemic use.
๐คฑ Lactation Safety
Caution; excreted in breast milk but unlikely to cause adverse effects in infant.
๐ Overdose Management
Topical overdose unlikely; accidental ingestion may cause nausea, vomiting, headache; supportive care.
โฐ Missed Dose
Apply as soon as remembered; if near next dose, skip missed dose and resume regular schedule.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for acirax cream
View AllAlternative brands with exact same active ingredient (Acyclovir (5% w/w)):
-
cloviderm ointmentNovartis India Ltd โน18.75 63.6% CHEAPER
-
acloriv 5% creamEast African (India) Overseas โน34.69 32.7% CHEAPER
-
herporax ointmentBiocare Remedies โน35.50 31.1% CHEAPER
-
setuvir creamSunways India Pvt Ltd โน36.40 29.4% CHEAPER
-
aciherpin creamAGIO Pharmaceuticals Ltd โน39.38 23.6% CHEAPER
-
zovistar creamMonichem Healthcare Pvt Ltd โน40.38 21.7% CHEAPER
-
acylab 5% creamLaborate Pharmaceuticals India Ltd โน42.50 17.6% CHEAPER
-
cyclopiz creamGary Pharmaceuticals Pvt Ltd โน46.88 9.1% CHEAPER
-
glenvirax creamGlenmark Pharmaceuticals Ltd โน48.00 6.9% CHEAPER
-
clovy creamAja Life โน49.00 5% CHEAPER
Medical Note: Always consult your doctor before switching medications.