amotus syrup - Ammonium Chloride (60mg/5ml) + Chlorpheniramine Maleate (2.5mg/5ml) medicine

amotus syrup - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Cure Tech Skincare ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 27, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 27, 2026

What is amotus syrup used for?

Amotus Syrup (Ammonium Chloride + Chlorpheniramine Maleate) is used to treat RESPIRATORY. It contains Ammonium Chloride (60mg/5ml) + Chlorpheniramine Maleate (2.5mg/5ml), which Ammonium Chloride: Increases respiratory tract fluid, reduces mucus viscosity; C. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Ammonium Chloride + Chlorpheniramine Maleate
  • Manufacturer: Cure Tech Skincare
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š amotus syrup Uses & Benefits

Symptomatic relief of cough associated with respiratory tract infections, allergic rhinitis, common cold

Off-label uses: Sedation, Motion sickness

๐Ÿ“‹ Drug Information

Generic Name(s)Ammonium Chloride + Chlorpheniramine Maleate
Brand NameAmotus Syrup
ManufacturerCure Tech Skincare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassExpectorant and Antihistamine
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light and moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed from gastrointestinal tract
DistributionDistributed throughout body; crosses blood-brain barrier
Protein BindingChlorpheniramine: ~72% protein bound
MetabolismChlorpheniramine: Hepatic via CYP450; Ammonium Chloride: Metabolized in liver to urea and hydrochloric acid
Half-LifeChlorpheniramine: 14-24 hours; Ammonium Chloride: Variable
ExcretionChlorpheniramine: Renal (as metabolites); Ammonium Chloride: Renal (as ammonium and chloride ions)
BioavailabilityChlorpheniramine: ~25-50%
Onset of ActionChlorpheniramine: 30-60 minutes
Peak Plasma TimeChlorpheniramine: 2-6 hours
Duration of ActionChlorpheniramine: 4-6 hours

How It Works

Ammonium Chloride: Increases respiratory tract fluid, reduces mucus viscosity; Chlorpheniramine: Competitively blocks histamine H1 receptors

Mechanism Steps

1Ammonium Chloride is absorbed and metabolized in the liver, producing urea and hydrochloric acid, which acidifies urine and increases respiratory tract fluid secretion.
2Chlorpheniramine Maleate competitively blocks histamine H1 receptors, preventing histamine-mediated effects such as vasodilation, increased capillary permeability, and bronchoconstriction.
3The combination reduces cough reflex by thinning mucus and suppressing histamine-induced symptoms.

๐Ÿ’ก How to Take amotus syrup

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of amotus syrup

โœ… Common Side Effects

  • Drowsiness
  • Dizziness
  • Dry mouth
  • Nausea
  • Thickened bronchial secretions

๐Ÿšจ Serious Side Effects

  • Respiratory depression
  • Severe hypotension
  • Arrhythmias
  • Seizures
  • Urinary retention

โš ๏ธ Rare Side Effects

  • Blood dyscrasias
  • Anaphylaxis
  • Hepatotoxicity

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
MAOIs Major Hypertensive crisis, increased anticholinergic effects
CNS Depressants Major Additive sedation and respiratory depression
Alcohol Major Enhanced CNS depression
Anticholinergics Moderate Additive anticholinergic effects
Tricyclic Antidepressants Moderate Increased anticholinergic and sedative effects
Antihypertensives Minor Possible reduced antihypertensive effect
Diuretics Minor Possible electrolyte imbalance

๐Ÿšจ Major Interactions

  • MAOIs
  • CNS Depressants
  • Alcohol

โšก Moderate Interactions

  • Anticholinergics
  • Tricyclic Antidepressants

โ„น๏ธ Minor Interactions

  • Antihypertensives
  • Diuretics

๐Ÿฝ๏ธ Food Interactions

None significant

๐Ÿท Alcohol Interaction

Increased CNS depression

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to any component, severe hypertension, coronary artery disease, MAOI use within 14 days, narrow-angle glaucoma, urinary retention, peptic ulcer, asthma attack

๐Ÿ“Š Monitoring Parameters

Respiratory status, CNS depression, anticholinergic effects, blood pressure

๐Ÿคฑ Lactation Safety

Caution; Chlorpheniramine excreted in breast milk

๐Ÿ’Š Overdose Management

Induce emesis or gastric lavage; administer activated charcoal; supportive care; for severe anticholinergic symptoms, physostigmine may be used

โฐ Missed Dose

Take as soon as remembered unless near next dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 27, 2026

๐Ÿ”— View Profile

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