amnos 10mg/10mg tablet - Doxylamine (10mg) + Vitamin B6 (Pyridoxine) (10mg) medicine

Amnos 10mg/10mg Tablet - Uses, Price, Side Effects

No reviews yet
๐Ÿญ Unichem Laboratories Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 28, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 28, 2026

What is amnos 10mg/10mg tablet used for?

Amnos 10mg/10mg Tablet is a combination of Doxylamine (an antihistamine) and Vitamin B6 (Pyridoxine). It is used to prevent and treat nausea and vomiting during pregnancy (morning sickness). Doxylamine works by blocking histamine receptors in the brain, reducing the vomiting reflex, while Vitamin B6 helps regulate neurotransmitters involved in nausea.

  • Generic Name: Doxylamine + Vitamin B6
  • Manufacturer: Unichem Laboratories Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š amnos 10mg/10mg tablet Uses & Benefits

Nausea and vomiting in pregnancy.

Off-label uses: Insomnia, Allergic rhinitis

๐Ÿ“‹ Drug Information

Generic Name(s)Doxylamine + Vitamin B6
Brand NameAct NVP Tablet
ManufacturerUnichem Laboratories Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassAntihistamine + Vitamin Supplement
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed from the gastrointestinal tract.
DistributionDistributes widely in body tissues; crosses the placenta.
Protein BindingDoxylamine: ~50% bound to plasma proteins; Pyridoxine: minimal binding.
MetabolismDoxylamine: Hepatic via CYP450; Pyridoxine: Hepatic to pyridoxal phosphate.
Half-LifeDoxylamine: 10-12 hours; Pyridoxine: 15-20 days.
ExcretionDoxylamine: Renal (as metabolites); Pyridoxine: Renal (as metabolites).
BioavailabilityDoxylamine: ~70%; Pyridoxine: ~80%.
Onset of Action30-60 minutes.
Peak Plasma TimeDoxylamine: 2-3 hours; Pyridoxine: 1-2 hours.
Duration of Action4-6 hours.

How It Works

Doxylamine: H1-receptor antagonist; Pyridoxine: cofactor for neurotransmitter synthesis.

Mechanism Steps

1Doxylamine competitively blocks histamine at H1 receptors in the vomiting center.
2Pyridoxine acts as a cofactor for enzymes involved in neurotransmitter synthesis, reducing nausea.
3Combined effect reduces emetic signals and provides sedation.

๐Ÿ’ก How to Take amnos 10mg/10mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of amnos 10mg/10mg tablet

โœ… Common Side Effects

  • Drowsiness
  • Dry mouth
  • Dizziness
  • Constipation

๐Ÿšจ Serious Side Effects

  • Severe allergic reaction
  • Urinary retention
  • Blurred vision

โš ๏ธ Rare Side Effects

  • Blood dyscrasias
  • Hepatotoxicity

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Alcohol Moderate Increased drowsiness
CNS Depressants Moderate Enhanced sedative effect
MAO Inhibitors Major Risk of hypertensive crisis

๐Ÿšจ Major Interactions

  • CNS depressants
  • MAO inhibitors

โšก Moderate Interactions

  • Anticholinergics
  • Alcohol

โ„น๏ธ Minor Interactions

  • Oral contraceptives
  • Isoniazid

๐Ÿฝ๏ธ Food Interactions

Grapefruit juice may increase absorption

๐Ÿท Alcohol Interaction

Increased sedation and CNS depression.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity to doxylamine or pyridoxine; narrow-angle glaucoma; urinary retention; asthma attack.

๐Ÿ“Š Monitoring Parameters

Nausea/vomiting relief; sedation level; anticholinergic effects.

๐Ÿคฑ Lactation Safety

Use with caution; may cause drowsiness in infant.

๐Ÿ’Š Overdose Management

Symptomatic and supportive; activated charcoal if recent ingestion; monitor for CNS depression and anticholinergic effects.

โฐ Missed Dose

Take as soon as remembered unless near next dose; skip if close to next dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 28, 2026

๐Ÿ”— View Profile

๐Ÿ˜Š Was this information helpful?

Browse Medicines A-Z

Search our extensive medical database alphabetically.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory
SaathiMed App
SaathiMed App Consult doctors & order medicines faster
Install