Amlovas Sn 5 Mg/2.5 Mg Tablet: Complete Guide To Uses, Side Effects, And Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe dizziness or fainting
- Very slow or irregular heartbeat
- Difficulty breathing or wheezing
- Swelling of face, lips, or throat
- Chest pain or worsening angina
- Sudden weight gain or swelling in legs
- Yellowing of skin or eyes
If experiencing severe symptoms, call emergency services immediately.
What is amlovas sn 5 mg/2.5 mg tablet used for?
This medicine is a combination of nebivolol and amlodipine used to treat high blood pressure. It works by relaxing blood vessels and slowing the heart rate, reducing the heart's workload. It is taken once daily orally.
- Generic Name: Nebivolol + Amlodipine
- Manufacturer: Macleods Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 amlovas sn 5 mg/2.5 mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा उच्च रक्तचाप (हाइपरटेंशन) के इलाज के लिए इस्तेमाल की जाती है। यह नेबिवोलोल और एम्लोडिपिन का संयोजन है, जो रक्त वाहिकाओं को आराम देकर और हृदय की गति को धीमा करके रक्तचाप को कम करती है। यह दिल के दौरे और स्ट्रोक के जोखिम को कम करने में मदद करती है। इसे रोजाना एक बार मौखिक रूप से लिया जाता है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, चक्कर आना, थकान और पैरों में सूजन शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको बेहोशी, धड़कन बहुत धीमी होना, या सांस लेने में कठिनाई हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे अचानक बंद न करें, क्योंकि इससे एनजाइना या दिल का दौरा पड़ सकता है। शराब का सेवन न करें। खड़े होते समय धीरे-धीरे उठें ताकि चक्कर न आए। यदि आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें। नियमित रूप से रक्तचाप और हृदय गति की जांच कराएं।
💊 amlovas sn 5 mg/2.5 mg tablet Uses & Benefits
[{"condition":"Hypertension","description":"This medicine is used to lower high blood pressure, reducing the risk of stroke, heart attack, and kidney damage.","evidence":"Well-established"},{"condition":"Angina pectoris","description":"It may be prescribed to relieve chest pain caused by reduced blood flow to the heart, though the combination is not first-line for this indication.","evidence":"Moderate"},{"condition":"Heart failure","description":"Nebivolol, a component of this medicine, is sometimes used in stable heart failure to improve survival, but the combination with amlodipine is not standard for this use.","evidence":"Limited"}]
Off-label uses: [{"condition":"Migraine prophylaxis","description":"Beta-blockers like nebivolol are sometimes used off-label to prevent migraines, but evidence for the combination is lacking.","evidence":"Limited"},{"condition":"Anxiety with palpitations","description":"The beta-blocking component may help reduce physical symptoms of anxiety such as rapid heartbeat, but this is not a primary indication.","evidence":"Limited"}]
Primary treatment for: Hypertension
Also treats: Angina pectoris, Heart failure (stable)
📋 Drug Information
| Generic Name(s) | Nebivolol + Amlodipine |
| Brand Name | Amlovas SN 5 mg/2.5 mg Tablet |
| Manufacturer | Macleods Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Antihypertensive combination (Beta-blocker + Calcium channel blocker) |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antihypertensive agents with complementary mechanisms. Nebivolol is a cardioselective beta-1 adrenergic receptor blocker that also causes vasodilation by stimulating beta-3 receptors and increasing nitric oxide release. Amlodipine is a dihydropyridine calcium channel blocker that inhibits the influx of calcium ions into vascular smooth muscle and cardiac muscle cells, leading to relaxation of blood vessels and reduced peripheral resistance. Together, they lower blood pressure by reducing heart rate, cardiac output, and vascular resistance.
Mechanism Steps
💡 How to Take amlovas sn 5 mg/2.5 mg tablet
Strength: Tablet containing Nebivolol 5 mg and Amlodipine 2.5 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally once daily, preferably at the same time each day. The dose may be adjusted by your doctor based on your blood pressure response and tolerability. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not change the dose without consulting your doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially dizziness and low blood pressure. Start with a lower dose and monitor closely. Dose must be individualized by a qualified clinician. |
| Renal Impairment | In patients with renal impairment, dose adjustment may be necessary. For moderate to severe renal impairment, a lower initial dose is recommended. Consult your doctor for individualized dosing. |
| Hepatic Impairment | In patients with hepatic impairment, this medicine should be used with caution. A lower initial dose is recommended, and gradual titration is advised. Consult your doctor for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet of this strength (nebivolol 5 mg and amlodipine 2.5 mg) once daily. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of amlovas sn 5 mg/2.5 mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Fluoxetine | Major | |
| Ketoconazole | Major | |
| Verapamil | Major | |
| Digoxin | Major | |
| Clonidine | Major | |
| Ibuprofen | Moderate | |
| Prazosin | Moderate | |
| Amitriptyline | Moderate | |
| Insulin | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- CYP2D6 inhibitors (e.g., fluoxetine, paroxetine, quinidine)
- CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin, ritonavir)
- Calcium channel blockers (e.g., verapamil, diltiazem)
- Digoxin
- Clonidine
⚡ Moderate Interactions
- NSAIDs (e.g., ibuprofen, naproxen)
- Alpha-blockers (e.g., prazosin, terazosin)
- Tricyclic antidepressants (e.g., amitriptyline)
- Antidiabetic drugs (e.g., insulin, metformin)
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it can intensify the blood pressure-lowering effect, leading to dizziness, fainting, and increased risk of falls. It may also worsen side effects such as drowsiness and fatigue.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe bradycardia","Second- or third-degree heart block","Cardiogenic shock","Severe liver disease","Known hypersensitivity to nebivolol or amlodipine","Severe hypotension","Pregnancy (second and third trimesters)","Breastfeeding"]
⚠️ Warnings & Precautions
["Do not stop this medicine abruptly, as it can worsen angina or cause a heart attack.","Use with caution in patients with asthma or COPD; beta-blockers may cause bronchospasm.","May mask symptoms of hypoglycemia in diabetic patients.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Use with caution in patients with liver or kidney disease; dose adjustment may be needed.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Avoid alcohol while taking this medicine.","Regular monitoring of blood pressure, heart rate, and laboratory parameters is advised."]
🤱 Lactation Safety
Nebivolol and amlodipine are excreted in breast milk. Breastfeeding is not recommended while taking this medicine unless clearly necessary. Consult your doctor to discuss alternatives.
💊 Overdose Management
Overdose of this medicine can cause severe hypotension, bradycardia, heart failure, and bronchospasm. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and may include activated charcoal, intravenous fluids, atropine for bradycardia, and vasopressors for hypotension. Hemodialysis is not effective for removing nebivolol or amlodipine.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.
Additional Safety Advice
Always take this medicine exactly as prescribed by your doctor. Do not stop taking it abruptly, as sudden withdrawal of nebivolol can worsen angina or lead to a heart attack. If you need to discontinue, your doctor will gradually reduce the dose. Avoid drinking alcohol while on this medicine, as it can enhance the blood pressure-lowering effect and cause dizziness. Stand up slowly from a sitting or lying position to prevent dizziness due to low blood pressure. Inform your doctor if you have asthma, liver disease, kidney disease, or diabetes, as this medicine may need dose adjustments or alternative therapy. Regular monitoring of blood pressure, heart rate, and kidney function is advised. Do not use potassium supplements or salt substitutes containing potassium without consulting your doctor, as nebivolol can increase potassium levels. If you are pregnant, planning to become pregnant, or breastfeeding, discuss with your doctor before using this medicine. Keep this medicine out of reach of children and store it in its original packaging at room temperature.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the blood pressure-lowering effects and dizziness. Start with a lower dose and monitor closely. Regular monitoring of kidney function and electrolytes is advised.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy, especially in the second and third trimesters, as it may harm the fetus. If you are planning pregnancy, consult your doctor to switch to a safer alternative before conception.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents and affect blood pressure and heart rate during surgery. Your doctor may advise temporary discontinuation or dose adjustment.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. It may cause dry mouth or affect blood pressure during dental procedures. Local anesthetics with epinephrine should be used with caution.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe and beneficial while taking this medicine. However, avoid sudden strenuous activities, especially in hot weather, as this can cause dizziness or low blood pressure. Stay hydrated and warm up properly before exercising. If you experience chest pain, severe shortness of breath, or dizziness during exercise, stop and seek medical attention.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue, especially when you first start taking it. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal work activities with caution. If your job involves operating machinery or driving, discuss with your doctor.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects or your doctor decides to discontinue, the dose will be gradually reduced to prevent rebound hypertension or angina. Always follow your doctor's instructions.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe when monitored appropriately. Regular check-ups are needed to monitor blood pressure, heart rate, kidney and liver function, and electrolyte levels. Some patients may develop tolerance or need dose adjustments over time. Lifestyle modifications remain important for long-term blood pressure control.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, weight loss, and stress reduction can help lower blood pressure and may reduce the need for medication.
Evidence: Well-establishedACE inhibitors, ARBs, diuretics, or other combinations may be alternatives if this medicine is not suitable.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you have a fever or acute illness, consult your doctor before vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or moisture. If crossing time zones, consult your doctor about adjusting the timing of your dose. Carry enough supply for the entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood pressure within 1-2 hours, but the full effect may take 1-2 weeks. Continue taking it regularly as prescribed.
A: No, do not stop without consulting your doctor. High blood pressure often has no symptoms, and stopping suddenly can be dangerous.
A: If you remember within 12 hours, take it. If more than 12 hours have passed, skip it and continue with your next scheduled dose. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for amlovas sn 5 mg/2.5 mg tablet
View AllAlternative brands with exact same active ingredient:
-
nebawol-sa 5/2.5 tabletCare Formulation Labs Pvt Ltd ₹126.56 116.1% COSTLIER
-
nebipil sa tabletAlkem Laboratories Ltd ₹137.34 134.5% COSTLIER
-
nebivol sa 5mg/2.5mg tabletKnoll Pharmaceuticals Ltd ₹159.60 172.5% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure high blood pressure permanently.
Fact: This medicine helps manage high blood pressure but does not cure it. Lifestyle changes and continued medication are often needed. - Myth: You can stop taking this medicine once your blood pressure is normal.
Fact: Stopping suddenly can cause a dangerous rise in blood pressure or heart problems. Always consult your doctor before stopping. - Myth: This medicine causes weight gain.
Fact: Weight gain is not a common side effect of this medicine. Some patients may experience fluid retention, which can be managed.
🔄 Alternative Options
Generic Alternatives
- Nebivolol 5 mg + Amlodipine 2.5 mg tablet (generic)
Brand Alternatives
- Amlovas SN 5 mg/2.5 mg tablet