amlomet 5mg/50mg tablet - Uses, Price, Side Effects & Substitutes
What is amlomet 5mg/50mg tablet used for?
Amtas-M 50 Tablet PR (Amlodipine + Metoprolol Succinate) is used to treat Hypertension. It contains Amlodipine (5mg) + Metoprolol Succinate (50mg), which Amlodipine inhibits calcium influx across cell membranes, causing vasodilation; . Always consult your doctor before use. Take as prescribed.
- Generic Name: Amlodipine + Metoprolol Succinate
- Manufacturer: Pulse Pharmaceuticals
- Medicine Form: Allopathy
- Pregnancy Category: A
🇮🇳 amlomet 5mg/50mg tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)
amlomet 5mg/50mg tablet का उपयोग मुख्य रूप से cardiac और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Amlodipine (5mg) + Metoprolol Succinate (50mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।
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📋 Drug Information
| Generic Name(s) | Amlodipine + Metoprolol Succinate |
|---|---|
| Brand Name | Amtas-M 50 Tablet PR |
| Manufacturer | Pulse Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Antihypertensive combination (Calcium channel blocker + Beta-blocker) |
| Route of Administration | Oral |
| Storage | Store at 20-25°C, protect from light and moisture. |
| Shelf Life | As per manufacturer |
🔬 Pharmacology (PK/PD)
Pharmacokinetics
Pharmacodynamics
💡 How and when to take amlomet 5mg/50mg tablet?
Follow your doctor's prescription exactly.
- ✅ Take exactly as prescribed by your doctor.
- ✅ Do not exceed the recommended dose
- ✅ Complete the full course of medication
- ✅ Store at 20-25°C, protect from light and moisture.
⚙️ How amlomet 5mg/50mg tablet Works
Amlodipine inhibits calcium influx across cell membranes, causing vasodilation; Metoprolol selectively blocks beta-1 adrenergic receptors, reducing heart rate and contractility.
💊 amlomet 5mg/50mg tablet Uses in Hindi (Ke Fayde), Benefits & Indications
Hypertension, stable angina, chronic heart failure (metoprolol).
Off-label uses: Migraine prophylaxis (metoprolol), Raynaud's phenomenon (amlodipine).
⚠️ What are the side effects of amlomet 5mg/50mg tablet?
✅ Common Side Effects
- Edema
- Dizziness
- Fatigue
- Headache
- Nausea
- Bradycardia
🚨 Serious Side Effects
- Heart block
- Severe hypotension
- Bronchospasm
- Hepatotoxicity
⚠️ Rare Side Effects
- Leukopenia
- Thrombocytopenia
- Stevens-Johnson syndrome
- Pulmonary fibrosis
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| ⚠️ Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | Increased amlodipine levels, risk of toxicity |
| Fluoxetine | Major | Increased metoprolol levels, bradycardia |
| NSAIDs | Moderate | Reduced antihypertensive effect |
| Digoxin | Moderate | Increased risk of bradycardia |
| Grapefruit juice | Minor | Increased amlodipine absorption |
🚨 Major Interactions
- CYP3A4 inhibitors (e.g., ketoconazole)
- CYP2D6 inhibitors (e.g., fluoxetine)
- Beta-blockers (additive bradycardia)
- Calcium channel blockers (additive hypotension)
⚡ Moderate Interactions
- NSAIDs
- Digoxin
- Clonidine
- Cimetidine
ℹ️ Minor Interactions
- Grapefruit juice (amlodipine)
- Antacids
- Rifampin
🍽️ Food Interactions
Grapefruit juice may increase amlodipine levels; avoid high-fat meals with metoprolol.
🍷 Alcohol Interaction
May enhance hypotensive effects; avoid excessive alcohol.
🛡️ Safety & Warnings
🚫 Contraindications
Hypersensitivity, cardiogenic shock, severe bradycardia, heart block, sick sinus syndrome, uncontrolled heart failure, severe hypotension.
📊 Monitoring Parameters
Blood pressure, heart rate, ECG, renal function, liver enzymes.
🤱 Lactation Safety
Excreted in breast milk; use with caution.
💊 Overdose Management
Supportive care; atropine for bradycardia, vasopressors for hypotension, calcium gluconate for amlodipine overdose.
⏰ Missed Dose
Take as soon as remembered; skip if near next dose; do not double.
🛑 Myths vs. Facts about amlomet 5mg/50mg tablet
- Myth: Generic substitutes of amlomet 5mg/50mg tablet are less effective.
Fact: Approved generic medicines contain the exact same active ingredients (Amlodipine (5mg) + Metoprolol Succinate (50mg)) and are just as safe and effective as the branded version. - Myth: Taking a double dose will cure my symptoms faster.
Fact: Taking more than the prescribed dose of amlomet 5mg/50mg tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage. - Myth: This medicine is 100% safe for everyone.
Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.
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