Amtas-M 50 Tablet: Comprehensive Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Fainting or severe dizziness
- Difficulty breathing or wheezing
- Chest pain that worsens or is not relieved by rest
- Very slow pulse (below 50 beats per minute)
- Swelling of face, lips, tongue, or throat
- Yellowing of skin or eyes
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is amlogard met 5mg/50mg tablet used for?
This medicine is a combination of Amlodipine and Metoprolol Succinate used to treat high blood pressure and prevent angina. It works by relaxing blood vessels and slowing the heart rate.
- Generic Name: Amlodipine + Metoprolol Succinate
- Manufacturer: Pfizer Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 amlogard met 5mg/50mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा उच्च रक्तचाप (हाइपरटेंशन) और एंजाइना (सीने में दर्द) के इलाज के लिए इस्तेमाल की जाती है। यह रक्त वाहिकाओं को आराम देकर रक्तचाप को कम करती है और हृदय की गति को धीमा करके हृदय पर दबाव कम करती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में चक्कर आना, थकान, सिरदर्द, पैरों में सूजन, धीमी हृदय गति, मतली और चेहरे पर लालिमा शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन यदि आपको बेहोशी, सांस लेने में कठिनाई, सीने में दर्द या बहुत धीमी नाड़ी महसूस हो तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे अचानक बंद न करें, क्योंकि इससे एंजाइना या दिल का दौरा पड़ सकता है। शराब से बचें क्योंकि इससे चक्कर और निम्न रक्तचाप बढ़ सकता है। यदि आपको अस्थमा, मधुमेह, लीवर या किडनी की बीमारी है तो अपने डॉक्टर को बताएं। नियमित रूप से रक्तचाप और नाड़ी की जांच करें।
💊 amlogard met 5mg/50mg tablet Uses & Benefits
- [{"condition":"Hypertension","description":"This medicine is used to lower high blood pressure when monotherapy is insufficient.
- It reduces both systolic and diastolic blood pressure.","evidence":"Well-established"},{"condition":"Chronic stable angina","description":"This medicine helps prevent chest pain by reducing heart rate and myocardial oxygen demand, and by dilating coronary arteries.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Heart rate control in atrial fibrillation","description":"Metoprolol component may be used off-label to control heart rate in patients with atrial fibrillation, but combination with amlodipine is not standard for this indication.","evidence":"Limited"}]
Primary treatment for: Hypertension
Also treats: Angina pectoris, Coronary artery disease
📋 Drug Information
| Generic Name(s) | Amlodipine + Metoprolol Succinate |
| Brand Name | Amtas-M 50 Tablet PR |
| Manufacturer | Pfizer Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Antihypertensive combination (Calcium channel blocker + Beta-blocker) |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Amlodipine inhibits the influx of calcium ions into vascular smooth muscle and cardiac muscle, causing peripheral arterial vasodilation and reduced peripheral vascular resistance. Metoprolol Succinate selectively blocks beta-1 adrenergic receptors in the heart, reducing heart rate, contractility, and cardiac output. Together, they lower blood pressure and decrease myocardial oxygen demand.
Mechanism Steps
💡 How to Take amlogard met 5mg/50mg tablet
Strength: Tablet containing Amlodipine 5 mg and Metoprolol Succinate 50 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet once daily, taken orally, with or without food. The dose may be adjusted by your doctor based on your blood pressure response and tolerance. Do not exceed the prescribed dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine. Start with a lower dose and titrate slowly. Monitor blood pressure and heart rate closely. |
| Renal Impairment | No specific dose adjustment is typically required for mild to moderate renal impairment. In severe renal impairment, use with caution and monitor closely. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Start with a lower dose and titrate slowly. Contraindicated in severe hepatic impairment. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet of 5 mg/50 mg. Do not exceed without medical advice. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of amlogard met 5mg/50mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| CYP3A4 inhibitors | Major | |
| CYP2D6 inhibitors | Major | |
| Verapamil | Major | |
| Diltiazem | Major | |
| NSAIDs | Moderate | |
| Alpha-blockers | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)
- CYP2D6 inhibitors (e.g., paroxetine, fluoxetine)
- Verapamil or diltiazem
⚡ Moderate Interactions
- NSAIDs
- Alpha-blockers
🍷 Alcohol Interaction
Alcohol may enhance the blood pressure-lowering and dizziness effects of this medicine. It is advisable to avoid or limit alcohol consumption while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe hypotension","Second- or third-degree heart block without pacemaker","Cardiogenic shock","Severe heart failure","Severe liver disease","Known hypersensitivity to amlodipine or metoprolol"]
⚠️ Warnings & Precautions
["Do not stop abruptly; taper gradually to avoid rebound angina or hypertension.","Use with caution in patients with asthma or COPD.","May mask symptoms of hypoglycemia in diabetics.","Avoid in patients with severe peripheral vascular disease.","Use with caution in elderly and those with renal impairment."]
🤱 Lactation Safety
Amlodipine and metoprolol are excreted in human breast milk. Caution is advised when used during breastfeeding. Consult your doctor to weigh benefits and risks.
💊 Overdose Management
Overdose may cause severe hypotension, bradycardia, heart failure, and bronchospasm. Seek immediate medical attention. Treatment is supportive and symptomatic, including intravenous fluids, atropine for bradycardia, and vasopressors if needed.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not stop taking it suddenly, as abrupt withdrawal of Metoprolol Succinate can worsen angina or cause a heart attack. Avoid alcohol while taking this medicine, as it can increase dizziness and low blood pressure. Inform your doctor if you have asthma, diabetes, liver disease, or kidney disease. Do not use potassium supplements without medical advice. Regularly monitor your blood pressure and heart rate as advised. If you miss a dose, follow your doctor's instructions; do not double the dose.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the blood pressure-lowering and heart rate-slowing effects. Start with a lower dose and monitor closely for dizziness and falls.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor. This medicine may not be suitable during pregnancy. Alternative treatments may be recommended.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthesia and affect blood pressure and heart rate during surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine, as it may cause dry mouth or affect blood pressure during dental procedures. Local anesthetics with epinephrine should be used with caution.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise initially as it may cause dizziness or fatigue. Gradually increase activity as tolerated. If you experience chest pain, shortness of breath, or severe dizziness during exercise, stop and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue, especially when starting treatment. Avoid driving or operating heavy machinery until you know how it affects you. Take it at the same time daily to minimize side effects.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Abrupt withdrawal can cause rebound hypertension or angina. Your doctor may taper the dose gradually if needed.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe when monitored. Regular check-ups for blood pressure, heart rate, and kidney function are recommended. It may increase the risk of new-onset diabetes, so blood sugar monitoring is advised. Do not stop without medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and stress reduction can help manage blood pressure and angina.
Evidence: Well-establishedACE inhibitors, ARBs, or diuretics may be alternatives if this combination is not suitable.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, consult your doctor before any vaccination while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If traveling across time zones, consult your doctor about adjusting the dosing schedule. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood pressure within 24 to 48 hours, but full effects may take 1 to 2 weeks.
A: Yes, you can take it with or without food, but be consistent. Avoid grapefruit juice.
A: If you remember within 12 hours, take it. If more than 12 hours, skip it and continue your regular schedule. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for amlogard met 5mg/50mg tablet
View AllAlternative brands with exact same active ingredient:
-
metolash am 5mg/50mg tabletZeelab Pharmacy Pvt Ltd ₹15.00 81.2% CHEAPER
-
davaindia amlodipine+metoprolol succinate 5mg/50mg tablet prDavaindia Generic Pharmacy ₹17.60 77.9% CHEAPER
-
bpdin mt 50 tablet erDR Best pharmaceuticals Pvt Ltd ₹23.44 70.6% CHEAPER
-
acmeto am 5mg/50mg tabletAcmedix Pharma LLP ₹25.31 68.2% CHEAPER
-
mepol-a 5mg/50mg tabletTaurus Laboratories Pvt Ltd ₹27.89 65% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be stopped once blood pressure is normal.
Fact: High blood pressure often requires long-term treatment. Stopping suddenly can cause rebound hypertension or angina. - Myth: This medicine is safe for everyone.
Fact: It is not suitable for people with certain heart, liver, or lung conditions. Always consult a doctor.
🔄 Alternative Options
Generic Alternatives
- Amlodipine + Metoprolol Succinate generic tablets
Brand Alternatives
- Amtas-M 50 Tablet PR